Recent development of small molecule glutaminase inhibitors M Song, SH Kim, CY Im, HJ Hwang Current topics in medicinal chemistry 18 (6), 432-443, 2018 | 104 | 2018 |
Insights of a lead optimization study and biological evaluation of novel 4-hydroxytamoxifen analogs as estrogen-related receptor γ (ERRγ) inverse agonists J Kim, SY Woo, CY Im, EK Yoo, S Lee, HJ Kim, HJ Hwang, J Cho, WS Lee, ... Journal of medicinal chemistry 59 (22), 10209-10227, 2016 | 23 | 2016 |
Synthesis and biological evaluation of novel 4-hydroxytamoxifen analogs as estrogen-related receptor gamma inverse agonists J Kim, J Chin, CY Im, EK Yoo, S Woo, HJ Hwang, J Cho, K Seo, J Song, ... European Journal of Medicinal Chemistry 120, 338-352, 2016 | 20 | 2016 |
Diversity-oriented routes to thiopeptide antibiotics: total synthesis and biological evaluation of micrococcin P2 HJ Hwang, YJ Son, D Kim, J Lee, YJ Shin, Y Kwon, MA Ciufolini Organic & Biomolecular Chemistry 20 (9), 1893-1899, 2022 | 13 | 2022 |
Pyrimethamine Derivatives: Insight into Binding Mechanism and Improved Enhancement of Mutant β-N-acetylhexosaminidase Activity MB Tropak, J Zhang, S Yonekawa, BA Rigat, VS Aulakh, MR Smith, ... Journal of medicinal chemistry 58 (11), 4483-4493, 2015 | 10 | 2015 |
Micrococcin P2 Targets Clostridioides difficile YJ Son, YR Kim, SH Oh, S Jung, MA Ciufolini, HJ Hwang, JH Kwak, H Pai Journal of Natural Products 85 (8), 1928-1935, 2022 | 5 | 2022 |
Silica Gel‐mediated Synthesis of β‐Enamino Esters and its Application for the Synthesis of Indeno 4‐Hydroxypyridin‐2 (1H)‐Ones SH Kim, S Bae, EB Ko, GY Park, E Lee, HJ Hwang, CY Im, M Song Bulletin of the Korean Chemical Society 40 (3), 262-269, 2019 | 5 | 2019 |
A Route to the Heterocyclic Cluster of the E-Series of Thiopeptide Antibiotics HJ Hwang, MA Ciufolini The Journal of Organic Chemistry 80 (8), 4184-4188, 2015 | 5 | 2015 |
Identification of Micrococcin P2-Derivatives as Antibiotic Candidates Against Two Gram-Positive Pathogens D Kim, J Lee, C Shyaka, JH Kwak, H Pai, M Rho, MA Ciufolini, M Han, ... Journal of Medicinal Chemistry 66 (20), 14263-14277, 2023 | 4 | 2023 |
Nitro-Group-Containing Thiopeptide Derivatives as Promising Agents to Target Clostridioides difficile D Kim, YR Kim, HJ Hwang, MA Ciufolini, J Lee, H Lee, S Clovis, S Jung, ... Pharmaceuticals 15 (5), 623, 2022 | 4 | 2022 |
Synthesis of a unique dimethyl thiazoline containing intermediate of novel peroxisome proliferator-activated receptors (PPAR) δ agonists TM Kadayat, G Lee, K Jung, HJ Hwang, J Joo, D Hahn, H Hwang, ... Tetrahedron letters 59 (50), 4384-4386, 2018 | 4 | 2018 |
Scaffold hopping strategy to derive 4‐hydroxy‐1‐alkyl‐2‐oxo‐1, 2‐dihydrothieno [2, 3‐b: 4, 5‐b′] dipyridine‐3‐carbonylglycine derivatives as a novel hypoxia‐inducible factor … GY Park, CH Park, SK Lee, CY Im, SH Kim, HJ Hwang, J Lee, T Lee, ... Bulletin of the Korean Chemical Society 44 (3), 202-207, 2023 | 2 | 2023 |
Heterologous Synthesis and Characterization of Thiocillin IV YJ Son, HJ Hwang, Y Kwon ACS Chemical Biology 18 (2), 265-272, 2023 | 2 | 2023 |
A Diversity-oriented Route to Micrococcins P1 and P2 for Medicinal Chemistry Investigations HJ Hwang, MA Ciufolini Targets Heterocycl. Syst 26, 154-169, 2022 | 1 | 2022 |
Chemical and biological studies on thiopeptide antibiotics: total synthesis of micrococcin P2 and synthetic efforts towards lactocillin HJ Hwang University of British Columbia, 2022 | 1 | 2022 |
Carboxamide derivative and pharmaceutical composition comprising same as active ingredient for preventing or treating mental illness M Song, CY Im, GY Park, EB Ko, K Jihee, BAE Seri, KIM Soong-Hyun, ... US Patent App. 17/928,044, 2024 | | 2024 |
Novel compound, preparation method thereof, and antibiotic composition comprising same HJ Hwang, YJ Son, KIM Dahyun, LEE Jusuk, M Ciufolini US Patent App. 18/037,102, 2023 | | 2023 |
2525. Identification of lead compounds, belonging to 26-membered thiopeptide antibiotics for new anti-tuberculosis therapeutic agents YJ Son, HJ Hwang, C Shyaka, D Kim, J Lee, S Eum, SK Lee Open Forum Infectious Diseases 10 (Supplement_2), ofad500. 2143, 2023 | | 2023 |
2518. Lead optimization on 26-membered thiopeptide antibiotics and identification of pre-clinical candidates against Clostridioides difficile and Staphylococcus aureus for impetigo HJ Hwang, YJ Son, D Kim, J Lee, C Shyaka, JH Kwak, H Pai, M Rho, ... Open Forum Infectious Diseases 10 (Supplement_2), ofad500. 2136, 2023 | | 2023 |
Therapies from Thiopeptides HJ Hwang, MA Ciufolini Molecules 28 (22), 7579, 2023 | | 2023 |