| Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 3525 | 2013 |
| Synaptic, transcriptional and chromatin genes disrupted in autism S De Rubeis, X He, AP Goldberg, CS Poultney, K Samocha, ... Nature 515 (7526), 209-215, 2014 | 2184 | 2014 |
| Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ... Nature genetics 43 (5), 436-441, 2011 | 1883 | 2011 |
| Patterns and rates of exonic de novo mutations in autism spectrum disorders BM Neale, Y Kou, L Liu, A Ma’Ayan, KE Samocha, A Sabo, CF Lin, ... Nature 485 (7397), 242-245, 2012 | 1845 | 2012 |
| Enhancing CD8 T-cell memory by modulating fatty acid metabolism EL Pearce, MC Walsh, PJ Cejas, GM Harms, H Shen, LS Wang, ... Nature 460 (7251), 103-107, 2009 | 1415 | 2009 |
| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 1288 | 2019 |
| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 1288 | 2019 |
| Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 685 | 2017 |
| Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy GU Höglinger, NM Melhem, DW Dickson, P Sleiman, LS Wang, L Klei, ... Nature genetics 43 (7), 699-705, 2011 | 518 | 2011 |
| Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions VM Van Deerlin, P Sleiman, M Martinez-Lage, A Chen-Plotkin, LS Wang, ... Nature genetics 42 (3), 234-239, 2010 | 486 | 2010 |
| Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes G Jun, AC Naj, GW Beecham, LS Wang, J Buros, PJ Gallins, JD Buxbaum, ... Archives of neurology 67 (12), 1473-1484, 2010 | 447 | 2010 |
| The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila N Liu, M Landreh, K Cao, M Abe, GJ Hendriks, JR Kennerdell, Y Zhu, ... Nature 482 (7386), 519-523, 2012 | 400 | 2012 |
| Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4, and the risk of late-onset Alzheimer disease in African Americans C Reitz, G Jun, A Naj, R Rajbhandary, BN Vardarajan, LS Wang, ... Jama 309 (14), 1483-1492, 2013 | 378 | 2013 |
| Apolipoprotein E genotype and sex risk factors for Alzheimer disease: a meta-analysis SC Neu, J Pa, W Kukull, D Beekly, A Kuzma, P Gangadharan, LS Wang, ... JAMA neurology 74 (10), 1178-1189, 2017 | 357 | 2017 |
| Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis DC Whitcomb, J LaRusch, AM Krasinskas, L Klei, JP Smith, RE Brand, ... Nature genetics 44 (12), 1349-1354, 2012 | 334 | 2012 |
| PASTA: ultra-large multiple sequence alignment for Nucleotide and Amino-acid sequences S Mirarab, N Nguyen, S Guo, LS Wang, J Kim, T Warnow Journal of Computational Biology 22 (5), 377-386, 2015 | 329 | 2015 |
| Genomic distribution and functional analyses of potential G-quadruplex-forming sequences in Saccharomyces cerevisiae SG Hershman, Q Chen, JY Lee, ML Kozak, P Yue, LS Wang, FB Johnson Nucleic acids research 36 (1), 144-156, 2008 | 303 | 2008 |
| Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders ET Lim, S Raychaudhuri, SJ Sanders, C Stevens, A Sabo, DG MacArthur, ... Neuron 77 (2), 235-242, 2013 | 263 | 2013 |
| A novel Alzheimer disease locus located near the gene encoding tau protein G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ... Molecular psychiatry 21 (1), 108-117, 2016 | 246 | 2016 |
| Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases G Coppola, S Chinnathambi, JJY Lee, BA Dombroski, MC Baker, ... Human molecular genetics 21 (15), 3500-3512, 2012 | 225 | 2012 |
Yuk Yee LeungUniversity of PennsylvaniaVerified email at pennmedicine.upenn.edu
