Follow
Thomas James O'Brien
Thomas James O'Brien
Research Associate at MRC Laboratory of Medical Sciences and Imperial College London
Verified email at ic.ac.uk
Title
Cited by
Cited by
Year
Decreased efficacy of antimicrobial agents in a polymicrobial environment
TJ O’Brien, W Figueroa, M Welch
The ISME Journal 16 (7), 1694-1704, 2022
272022
A continuous-flow model for in vitro cultivation of mixed microbial populations associated with cystic fibrosis airway infections
TJ O’Brien, M Welch
Frontiers in Microbiology 10, 498685, 2019
182019
Recapitulation of polymicrobial communities associated with cystic fibrosis airway infections: a perspective
TJ O'Brien, M Welch
Future Microbiology 14 (16), 1437-1450, 2019
182019
Brain monoamine vesicular transport disease caused by homozygous SLC18A2 variants: A study in 42 affected individuals
K Saida, R Maroofian, T Sengoku, T Mitani, AT Pagnamenta, D Marafi, ...
Genetics in Medicine 25 (1), 90-102, 2023
172023
Megapixel camera arrays enable high-resolution animal tracking in multiwell plates
IL Barlow, L Feriani, E Minga, A McDermott-Rouse, TJ O’Brien, Z Liu, ...
Communications biology 5 (1), 253, 2022
16*2022
Bi-allelic loss-of-function variants in PPFIBP1 cause a neurodevelopmental disorder with microcephaly, epilepsy, and periventricular calcifications
E Rosenhahn, TJ O’Brien, MS Zaki, I Sorge, D Wieczorek, K Rostasy, ...
The American Journal of Human Genetics 109 (8), 1421-1435, 2022
142022
An in vitro model for the cultivation of polymicrobial biofilms under continuous-flow conditions
TJ O'Brien, MM Hassan, F Harrison, M Welch
F1000Research 10, 2021
82021
Virulence and antimicrobial resistance genes are enriched in the plasmidome of clinical Escherichia coli isolates compared with wastewater isolates from western Kenya
SA Wawire, ON Reva, TJ O'Brien, W Figueroa, V Dinda, WA Shivoga, ...
Infection, Genetics and Evolution 91, 104784, 2021
72021
A new Caenorhabditis elegans model to study copper toxicity in Wilson disease
F Catalano, TJ O'Brien, AA Mekhova, LV Sepe, M Elia, R De Cegli, ...
Traffic 25 (1), e12920, 2024
12024
Response of Disease Model Mutants to Cholinergic Drugs
TJ O'Brien
12022
Reticulon 2 deficiency results in an autosomal recessive distal motor neuropathy with lower limb spasticity
R Maroofian, P Sarraf, TJ O’Brien, M Kamel, A Cakar, N Elkhateeb, T Lau, ...
Brain, awae091, 2024
2024
Whole genome sequencing and genotyping Klebsiella pneumoniae multi-drug resistant hospital isolates from Western Kenya
V Dinda, AN Kimang’a, D Kariuki, AW Sifuna, TJ O’Brien, M Welch, ...
Access Microbiology 6 (1), 000667. v4, 2024
2024
Systematic creation and phenotyping of Mendelian disease models in C. elegans: towards large-scale drug repurposing
TJ O’Brien, IL Barlow, L Feriani, AEX Brown
bioRxiv, 2023.08. 25.554786, 2023
2023
unc-80 LoF Mutant Drug Repurposing/Confirmation Screening
TJ O'Brien
2023
Screening effects of excess copper on worm behaviour
TJ O'Brien
2023
Reticulon Mutant Drug Screen
TJ O'Brien
2023
Pharyngeal Pumping Assay
TJ O'Brien
2022
In vitro Recapitulation of the Polymicrobial Communities Associated with Cystic Fibrosis Airway Infections
TJ O'Brien
2021
Prestwick screen protocol
TJ O'Brien, I Barlow
2021
An in vitro model for the cultivation of polymicrobial biofilm s under continuous-flow conditions [version 1; peer review
TJ O'Brien, MM Hassan, F Harrison, M Welch
2021
The system can't perform the operation now. Try again later.
Articles 1–20