| Senolytics reduce coronavirus-related mortality in old mice CD Camell, MJ Yousefzadeh, Y Zhu, LGPL Prata, MA Huggins, M Pierson, ... Science 373 (6552), eabe4832, 2021 | 216 | 2021 |
| Targeting cellular senescence with senotherapeutics: senolytics and senomorphics L Zhang, LE Pitcher, V Prahalad, LJ Niedernhofer, PD Robbins The FEBS journal 290 (5), 1362-1383, 2023 | 187 | 2023 |
| Cellular senescence: a key therapeutic target in aging and diseases L Zhang, LE Pitcher, MJ Yousefzadeh, LJ Niedernhofer, PD Robbins, ... The Journal of Clinical Investigation 132 (15), 2022 | 145 | 2022 |
| Regioselective synthesis of 3-benzazepinones and unexpected 5-bromo-3-benzazepinones L Zhang, D Ye, Y Zhou, G Liu, E Feng, H Jiang, H Liu The Journal of Organic Chemistry 75 (11), 3671-3677, 2010 | 92 | 2010 |
| Palladium-catalyzed difunctionalization of alkynes via C–N and S–N cleavages: A versatile approach to highly functional indoles F Zhao, D Zhang, Y Nian, L Zhang, W Yang, H Liu Organic letters 16 (19), 5124-5127, 2014 | 80 | 2014 |
| Gold (I)-catalyzed tandem transformation: A simple approach for the synthesis of pyrrolo/pyrido [2, 1-a][1, 3] benzoxazinones and pyrrolo/pyrido [2, 1-a] quinazolinones E Feng, Y Zhou, D Zhang, L Zhang, H Sun, H Jiang, H Liu The Journal of Organic Chemistry 75 (10), 3274-3282, 2010 | 77 | 2010 |
| ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging J Zhao, L Zhang, A Lu, Y Han, D Colangelo, C Bukata, A Scibetta, ... Aging (Albany NY) 12 (6), 4688, 2020 | 71 | 2020 |
| An expedient Pd/DBU mediated cyanation of aryl/heteroaryl bromides with K 4 [Fe (CN) 6] D Zhang, H Sun, L Zhang, Y Zhou, C Li, H Jiang, K Chen, H Liu Chemical communications 48 (23), 2909-2911, 2012 | 70 | 2012 |
| Rapid and selective access to three distinct sets of indole-based heterocycles from a single set of Ugi-adducts under microwave heating L Zhang, F Zhao, M Zheng, Y Zhai, H Liu Chemical communications 49 (28), 2894-2896, 2013 | 60 | 2013 |
| Gold‐and Silver‐Catalyzed Intramolecular Hydroamination of Terminal Alkynes: Water‐Triggered Chemo‐and Regioselective Synthesis of Fused Tricyclic Xanthines D Ye, X Zhang, Y Zhou, D Zhang, L Zhang, H Wang, H Jiang, H Liu Advanced Synthesis & Catalysis 351 (17), 2770-2778, 2009 | 60 | 2009 |
| ARDD 2020: from aging mechanisms to interventions GV Mkrtchyan, K Abdelmohsen, P Andreux, I Bagdonaite, N Barzilai, ... Aging (Albany NY) 12 (24), 24484, 2020 | 54 | 2020 |
| Synthesis of Pyrrolo[1,2-a]quinoxalines via Gold(I)-Mediated Cascade Reactions G Liu, Y Zhou, D Lin, J Wang, L Zhang, H Jiang, H Liu ACS Combinatorial Science 13 (3), 209-213, 2011 | 54 | 2011 |
| Gold-catalyzed tandem reaction in water: An efficient and convenient synthesis of fused polycyclic indoles E Feng, Y Zhou, F Zhao, X Chen, L Zhang, H Jiang, H Liu Green Chemistry 14 (7), 1888-1895, 2012 | 53 | 2012 |
| Recent advances in the discovery of senolytics L Zhang, LE Pitcher, V Prahalad, LJ Niedernhofer, PD Robbins Mechanisms of ageing and development 200, 111587, 2021 | 52 | 2021 |
| Discovery of small molecules as multi-toll-like receptor agonists with proinflammatory and anticancer activities L Zhang, V Dewan, H Yin Journal of Medicinal Chemistry 60 (12), 5029-5044, 2017 | 48 | 2017 |
| Asymmetric Michael Addition of N-tert-Butanesulfinyl Imidate with α,β-Unsaturated Diesters: Scope and Application to the Synthesis of Indanone Derivatives J Wang, Y Zhou, L Zhang, Z Li, X Chen, H Liu Organic letters 15 (7), 1508-1511, 2013 | 46 | 2013 |
| Benzamide derivatives as dual-action hypoglycemic agents that inhibit glycogen phosphorylase and activate glucokinase L Zhang, H Li, Q Zhu, J Liu, L Chen, Y Leng, H Jiang, H Liu Bioorganic & medicinal chemistry 17 (20), 7301-7312, 2009 | 45 | 2009 |
| Rapid generation of privileged substructure-based compound libraries with structural diversity and drug-likeness L Zhang, M Zheng, F Zhao, Y Zhai, H Liu ACS Combinatorial Science 16 (4), 184-191, 2014 | 44 | 2014 |
| Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation J Zhao, L Zhang, X Mu, C Doebelin, W Nguyen, C Wallace, DP Reay, ... PLoS biology 16 (6), e2004663, 2018 | 43 | 2018 |
| Gold(I)-Catalyzed Cascade Approach for the Synthesis of Tryptamine-Based Polycyclic Privileged Scaffolds as α1-Adrenergic Receptor Antagonists Z Li, J Li, N Yang, Y Chen, Y Zhou, X Ji, L Zhang, J Wang, X Xie, H Liu The Journal of Organic Chemistry 78 (21), 10802-10811, 2013 | 41 | 2013 |
