David Needham
David Needham
School of Engineering Duke University, and School of Pharmacy Nottingham UK
Verified email at - Homepage
Cited by
Cited by
Effect of chain length and unsaturation on elasticity of lipid bilayers
W Rawicz, KC Olbrich, T McIntosh, D Needham, E Evans
Biophysical journal 79 (1), 328-339, 2000
Physical properties of surfactant bilayer membranes: thermal transitions, elasticity, rigidity, cohesion and colloidal interactions
E Evans, D Needham
Journal of Physical Chemistry 91 (16), 4219-4228, 1987
Elastic deformation and failure of lipid bilayer membranes containing cholesterol
D Needham, RS Nunn
Biophysical journal 58 (4), 997-1009, 1990
A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model
D Needham, G Anyarambhatla, G Kong, MW Dewhirst
Cancer research 60 (5), 1197-1201, 2000
The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors
D Needham, MW Dewhirst
Advanced drug delivery reviews 53 (3), 285-305, 2001
Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release
G Kong, G Anyarambhatla, WP Petros, RD Braun, OM Colvin, D Needham, ...
Cancer research 60 (24), 6950-6957, 2000
Water permeability and mechanical strength of polyunsaturated lipid bilayers
K Olbrich, W Rawicz, D Needham, E Evans
Biophysical journal 79 (1), 321-327, 2000
Repulsive interactions and mechanical stability of polymer-grafted lipid membranes
D Needham, TJ McIntosh, DD Lasic
Biochimica et Biophysica Acta (BBA)-Biomembranes 1108 (1), 40-48, 1992
The" stealth" liposome: a prototypical biomaterial
DD Lasic, D Needham
Chemical reviews 95 (8), 2601-2628, 1995
Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue
NZ Wu, D Da, TL Rudoll, D Needham, AR Whorton, MW Dewhirst
Cancer research 53 (16), 3765-3770, 1993
Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly (ethylene glycol)
AK Kenworthy, K Hristova, D Needham, TJ McIntosh
Biophysical journal 68 (5), 1921-1936, 1995
Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors
AA Manzoor, LH Lindner, CD Landon, JY Park, AJ Simnick, MR Dreher, ...
Cancer research 72 (21), 5566-5575, 2012
Functional bionetworks from nanoliter water droplets
MA Holden, D Needham, H Bayley
Journal of the American Chemical Society 129 (27), 8650-8655, 2007
Structure and mechanical properties of giant lipid (DMPC) vesicle bilayers from 20. degree. C below to 10. degree. C above the liquid crystal-crystalline phase transition at 24 …
D Needham, E Evans
Biochemistry 27 (21), 8261-8269, 1988
Tension-stabilized pores in giant vesicles: determination of pore size and pore line tension
DV Zhelev, D Needham
Biochimica et Biophysica Acta (BBA)-Biomembranes 1147 (1), 89-104, 1993
Test of the Epstein− Plesset Model for gas microparticle dissolution in aqueous media: effect of surface tension and gas undersaturation in solution
PB Duncan, D Needham
Langmuir 20 (7), 2567-2578, 2004
Thermomechanical and transition properties of dimyristoylphosphatidylcholine/cholesterol bilayers
D Needham, TJ McIntosh, E Evans
Biochemistry 27 (13), 4668-4673, 1988
Electro-mechanical permeabilization of lipid vesicles. Role of membrane tension and compressibility
D Needham, RM Hochmuth
Biophysical journal 55 (5), 1001-1009, 1989
Nanoscale drug delivery and hyperthermia: the materials design and preclinical and clinical testing of low temperature-sensitive liposomes used in combination with mild …
CD Landon, JY Park, D Needham, MW Dewhirst
The open nanomedicine journal 3, 38, 2011
A synthetic mimic of the secretory granule for drug delivery
PF Kiser, G Wilson, D Needham
Nature 394 (6692), 459-462, 1998
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