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Jian-Ke Tie
Jian-Ke Tie
Verified email at email.unc.edu
Title
Cited by
Cited by
Year
Structural and functional insights into enzymes of the vitamin K cycle
JK Tie, DW Stafford
Journal of Thrombosis and Haemostasis 14 (2), 236-247, 2016
1392016
Membrane topology mapping of vitamin K epoxide reductase by in vitro translation/cotranslocation
JK Tie, C Nicchitta, G Von Heijne, DW Stafford
Journal of Biological Chemistry 280 (16), 16410-16416, 2005
1242005
Functional study of the vitamin K cycle in mammalian cells
JK Tie, DY Jin, DL Straight, DW Stafford
Blood, The Journal of the American Society of Hematology 117 (10), 2967-2974, 2011
1232011
The conversion of vitamin K epoxide to vitamin K quinone and vitamin K quinone to vitamin K hydroquinone uses the same active site cysteines
DY Jin, JK Tie, DW Stafford
Biochemistry 46 (24), 7279-7283, 2007
1022007
Structure and function of vitamin K epoxide reductase
JK Tie, DW Stafford
Vitamins & Hormones 78, 103-130, 2008
982008
A topological study of the human γ-glutamyl carboxylase
J Tie, SM Wu, D Jin, CV Nicchitta, DW Stafford
Blood, The Journal of the American Society of Hematology 96 (3), 973-978, 2000
732000
Evaluation of warfarin resistance using transcription activator‐like effector nucleases‐mediated vitamin K epoxide reductase knockout HEK293 cells
JK Tie, DY Jin, K Tie, DW Stafford
Journal of Thrombosis and Haemostasis 11 (8), 1556-1564, 2013
632013
Characterization of vitamin K–dependent carboxylase mutations that cause bleeding and nonbleeding disorders
JK Tie, JDA Carneiro, DY Jin, CD Martinhago, C Vermeer, DW Stafford
Blood, The Journal of the American Society of Hematology 127 (15), 1847-1855, 2016
622016
Human Vitamin K Epoxide Reductase and Its Bacterial Homologue Have Different Membrane Topologies and Reaction Mechanisms*♦
JK Tie, DY Jin, DW Stafford
Journal of Biological Chemistry 287 (41), 33945-33955, 2012
552012
Chemiluminescence investigation of the interaction of metalloporphyrins with nucleic acids
YX Ci, YG Zheng, JK Tie, WB Chang
Analytica chimica acta 282 (3), 695-701, 1993
541993
Warfarin and vitamin K epoxide reductase: a molecular accounting for observed inhibition
S Wu, X Chen, DY Jin, DW Stafford, LG Pedersen, JK Tie
Blood, The Journal of the American Society of Hematology 132 (6), 647-657, 2018
512018
Determination of disulfide bond assignment of human vitamin K-dependent γ-glutamyl carboxylase by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
JK Tie, VP Mutucumarana, DL Straight, KL Carrick, RM Pope, DW Stafford
Journal of Biological Chemistry 278 (46), 45468-45475, 2003
412003
The putative vitamin K-dependent γ-glutamyl carboxylase internal propeptide appears to be the propeptide binding site
PJ Lin, DY Jin, JK Tie, SR Presnell, DL Straight, DW Stafford
Journal of Biological Chemistry 277 (32), 28584-28591, 2002
372002
Functional study of the vitamin K cycle enzymes in live cells
JK Tie, DW Stafford
Methods in enzymology 584, 349-394, 2017
362017
A genome-wide CRISPR-Cas9 knockout screen identifies FSP1 as the warfarin-resistant vitamin K reductase
DY Jin, X Chen, Y Liu, CM Williams, LC Pedersen, DW Stafford, JK Tie
Nature Communications 14 (1), 828, 2023
302023
Conserved loop cysteines of vitamin K epoxide reductase complex subunit 1-like 1 (VKORC1L1) are involved in its active site regeneration
JK Tie, DY Jin, DW Stafford
Journal of Biological Chemistry 289 (13), 9396-9407, 2014
292014
Evaluation of oral anticoagulants with vitamin K epoxide reductase in its native milieu
X Chen, DY Jin, DW Stafford, JK Tie
Blood, The Journal of the American Society of Hematology 132 (18), 1974-1984, 2018
282018
Flow injection and liquid chromatographic postcolumn detection of amino acids by mimetic peroxidase-catalysed chemiluminescence reaction
YX Ci, JK Tie, QW Wang, WB Chang
Analytica chimica acta 269 (1), 109-114, 1992
281992
Cyclooctatetraene: a bioactive cubane paradigm complement
H Xing, SD Houston, X Chen, S Ghassabian, T Fahrenhorst‐Jones, A Kuo, ...
Chemistry–A European Journal 25 (11), 2729-2734, 2019
262019
γ-Glutamyl carboxylase mutations differentially affect the biological function of vitamin K–dependent proteins
Z Hao, DY Jin, X Chen, LJ Schurgers, DW Stafford, JK Tie
Blood, The Journal of the American Society of Hematology 137 (4), 533-543, 2021
252021
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