| Catalytic mechanism of the enzyme papain: predictions with a hybrid quantum mechanical/molecular mechanical potential MJ Harrison, NA Burton, IH Hillier Journal of the American Chemical Society 119 (50), 12285-12291, 1997 | 197 | 1997 |
| Wip1-deficient mice are resistant to common cancer genes M Harrison, J Li, Y Degenhardt, T Hoey, S Powers Trends in molecular medicine 10 (8), 359-361, 2004 | 63 | 2004 |
| Identification of a PPARδ agonist with partial agonistic activity on PPARγ RV Connors, Z Wang, M Harrison, A Zhang, M Wanska, S Hiscock, B Fox, ... Bioorganic & medicinal chemistry letters 19 (13), 3550-3554, 2009 | 56 | 2009 |
| Prediction of the mechanisms of enzyme-catalysed reactions using hybrid quantum mechanical/molecular mechanical methods NA Burton, MJ Harrison, JC Hart, IH Hillier Faraday Discussions 110, 463-475, 1998 | 47 | 1998 |
| Solvation and solid state effects on the structure and energetics of the tautomers of creatinine JS Craw, SP Greatbanks, IH Hillier, MJ Harrison, NA Burton The Journal of chemical physics 106 (16), 6612-6617, 1997 | 31 | 1997 |
| Mechanism and transition state structure for papain catalysed amide hydrolysis, using a hybrid QM/MM potential MJ Harrison, NA Burton, IH Hillier, IR Gould Chemical Communications, 2769-2770, 1996 | 30 | 1996 |
| Prediction of transition state structure in protein tyrosine phosphatase catalysis using a hybrid QM/MM potential JC Hart, NA Burton, IH Hillier, MJ Harrison, P Jewsbury Chemical Communications, 1431-1432, 1997 | 20 | 1997 |
| Discovery and optimization of a series of liver X receptor antagonists XY Jiao, DJ Kopecky, B Fisher, DE Piper, M Labelle, S McKendry, ... Bioorganic & medicinal chemistry letters 22 (18), 5966-5970, 2012 | 16 | 2012 |
| Discovery and characterization of MAPK-activated protein kinase-2 prevention of activation inhibitors JG Cumming, JE Debreczeni, F Edfeldt, E Evertsson, M Harrison, ... Journal of Medicinal Chemistry 58 (1), 278-293, 2015 | 12 | 2015 |
| Furanopyrimidines JL Buchanan, WH Buckner, SA Burkitt, EF DiMauro, CN Farthing, ... US Patent 7,776,867, 2010 | 9 | 2010 |
| Pyrrolo [2, 3-d] pyrimidines that modulate ACK1 activity CN Farthing, P Faulder, AD Frenkel, MJ Harrison, X Jiao, F Kayser, ... US Patent 7,358,250, 2008 | 9 | 2008 |
| Serine protease inhibitors SE Lively, B Waszkowycz, MJ Harrison, CN Farthing, KM Johnson US Patent 7,074,934, 2006 | 9 | 2006 |
| Serine protease inhibitors SE Lively, B Waszkowycz, MJ Harrison, CN Farthing, KM Johnson US Patent 7,157,585, 2007 | 8 | 2007 |
| Serine protease inhibitors SE Lively, MJ Harrison, NJ Naylor, CN Farthing, B Waszkowycz US Patent 7,067,516, 2006 | 8 | 2006 |
| Serine protease inhibitors SE Lively, B Waszkowycz, MJ Harrison, CN Farthing, KM Johnson US Patent 6,916,957, 2005 | 3 | 2005 |
| Receptor-based virtual screening of very large chemical datasets B Waszkowycz, T Perkins, C Baxter, R Sykes, J Li, M Harrison Rational Approaches to Drug Design, 372-381, 2001 | 3 | 2001 |
| Modelling of Transition States in Condensed Phase Reactivity Studies NA Burton, MJ Harrison, IH Hillier, NR Jones, D Tantanak, MA Vincent | 2 | 1999 |
| Modelling the enzyme papain: A hybrid QM/MM study MJ Harrison PQDT-Global, 1997 | 1 | 1997 |
| Serine protease inhibitors SE Lively, B Waszkowycz, MJ Harrison, CN Farthing, KM Johnson US Patent 7,381,734, 2008 | | 2008 |
| MEDI 239-Structure-guided design of pan-LXR antagonists F Kayser, A Chai, P Coward, M Harrison, J Jaen, XY Jiao, S Jones, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, 2008 | | 2008 |
