Asymmetric, catalytic synthesis of α-chiral amines using a novel bis (phosphine) monoxide chiral ligand AA Boezio, J Pytkowicz, A Côté, AB Charette Journal of the American chemical society 125 (47), 14260-14261, 2003 | 233 | 2003 |
Identification of a benzoisoxazoloazepine inhibitor (CPI-0610) of the bromodomain and extra-terminal (BET) family as a candidate for human clinical trials BK Albrecht, VS Gehling, MC Hewitt, RG Vaswani, A Côté, Y Leblanc, ... Journal of medicinal chemistry 59 (4), 1330-1339, 2016 | 210 | 2016 |
Disrupting acetyl-lysine recognition: progress in the development of bromodomain inhibitors FA Romero, AM Taylor, TD Crawford, V Tsui, A Côté, S Magnuson Journal of medicinal chemistry 59 (4), 1271-1298, 2016 | 187 | 2016 |
Catalytic asymmetric addition of diorganozinc reagents to N-phosphinoylalkylimines A Côté, AA Boezio, AB Charette Proceedings of the National Academy of Sciences 101 (15), 5405-5410, 2004 | 128 | 2004 |
Discovery, design, and optimization of isoxazole azepine BET inhibitors VS Gehling, MC Hewitt, RG Vaswani, Y Leblanc, A Côté, CG Nasveschuk, ... ACS medicinal chemistry letters 4 (9), 835-840, 2013 | 124 | 2013 |
Diving into the water: inducible binding conformations for BRD4, TAF1 (2), BRD9, and CECR2 bromodomains TD Crawford, V Tsui, EM Flynn, S Wang, AM Taylor, A Côté, JE Audia, ... Journal of Medicinal Chemistry 59 (11), 5391-5402, 2016 | 111 | 2016 |
Fragment-based discovery of a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor (CPI-637) AM Taylor, A Côté, MC Hewitt, R Pastor, Y Leblanc, CG Nasveschuk, ... ACS Medicinal Chemistry Letters 7 (5), 531-536, 2016 | 100 | 2016 |
General method for the expedient synthesis of salt-free diorganozinc reagents using zinc methoxide A Côté, AB Charette Journal of the American Chemical Society 130 (9), 2771-2773, 2008 | 100 | 2008 |
Discovery of a potent and selective in vivo probe (GNE-272) for the bromodomains of CBP/EP300 TD Crawford, FA Romero, KW Lai, V Tsui, AM Taylor, G de Leon Boenig, ... Journal of medicinal chemistry 59 (23), 10549-10563, 2016 | 91 | 2016 |
Application of the chiral bis (phosphine) monoxide ligand to catalytic enantioselective addition of dialkylzinc reagents to β-Nitroalkenes A Côté, VNG Lindsay, AB Charette Organic Letters 9 (1), 85-87, 2007 | 78 | 2007 |
Evidence for the Structure of the Enantioactive Ligand in the Phosphine–Copper‐Catalyzed Addition of Diorganozinc Reagents to Imines A Côté, AA Boezio, AB Charette Angewandte Chemie International Edition 43 (47), 6525-6528, 2004 | 74 | 2004 |
Regulatory T cell modulation by CBP/EP300 bromodomain inhibition S Ghosh, A Taylor, M Chin, HR Huang, AR Conery, JA Mertz, A Salmeron, ... Journal of Biological Chemistry 291 (25), 13014-13027, 2016 | 69 | 2016 |
Enantioselective synthesis of β-amino alcohols and α-amino acids via a copper catalyzed addition of diorganozinc reagents to N-phosphinoylimines JN Desrosiers, A Côté, AB Charette Tetrahedron 61 (26), 6186-6192, 2005 | 59 | 2005 |
Multicomponent one-pot procedure for the synthesis of free α-chiral amines from aldehydes A Côté, AB Charette The Journal of Organic Chemistry 70 (26), 10864-10867, 2005 | 58 | 2005 |
Method and apparatus for preparing pure water WW Carson, KJ Sims, B Mack, RJ Ritz, WC Whitehill US Patent 6,796,436, 2004 | 58 | 2004 |
Bromodomain inhibitors and uses thereof BK Albrecht, JE Audia, A Côté, VS Gehling, JC Harmange, MC Hewitt, ... US Patent 9,249,161, 2016 | 57 | 2016 |
Bromodomain inhibitors and uses thereof BK Albrecht, JE Audia, A Côté, VS Gehling, JC Harmange, MC Hewitt, ... US Patent 8,796,261, 2014 | 55 | 2014 |
Asymmetric catalytic addition of diorganozinc reagents to imines: Scope and application AB Charette, AA Boezio, A Côté, E Moreau, J Pytkowicz, JN Desrosiers, ... Pure and applied chemistry 77 (7), 1259-1267, 2005 | 49 | 2005 |
Automatic pan/tilt pointing device, luminaire follow-spot, and 6DOF 3D position/orientation calculation information W Bauer, R Lozano-Hemmer US Patent App. 10/155,764, 2002 | 43 | 2002 |
Preparation of enantiomerically enriched (1S)-1-phenylpropan-1-amine hydrochloride by a catalytic addition of diorganozinc reagents to imines:[Benzenemethanamine,-ethyl … JN Desrosiers, A Côté, AA Boezio, AB Charette, SE Denmark, ... Organic Syntheses 83, 5-17, 2006 | 40 | 2006 |