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Yanyan Cai
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The genomic landscape of endocrine-resistant advanced breast cancers
P Razavi, MT Chang, G Xu, C Bandlamudi, DS Ross, N Vasan, Y Cai, ...
Cancer cell 34 (3), 427-438. e6, 2018
8012018
HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers
BT Li, F Michelini, S Misale, E Cocco, L Baldino, Y Cai, S Shifman, HY Tu, ...
Cancer discovery 10 (5), 674-687, 2020
1772020
Loss of chromosome 8p governs tumor progression and drug response by altering lipid metabolism
Y Cai, J Crowther, T Pastor, LA Asbagh, MF Baietti, M De Troyer, ...
Cancer cell 29 (5), 751-766, 2016
1762016
Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination
M Steklov, S Pandolfi, MF Baietti, A Batiuk, P Carai, P Najm, M Zhang, ...
Science 362 (6419), 1177-1182, 2018
1532018
ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer
G Xu, S Chhangawala, E Cocco, P Razavi, Y Cai, JE Otto, L Ferrando, ...
Nature genetics 52 (2), 198-207, 2020
1522020
Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer
LM Smyth, SA Piha-Paul, HH Won, AM Schram, C Saura, S Loi, J Lu, ...
Cancer discovery 10 (2), 198-213, 2020
1072020
Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones
D Liang, Y Feng, F Zandkarimi, H Wang, Z Zhang, J Kim, Y Cai, W Gu, ...
Cell 186 (13), 2748-2764. e22, 2023
832023
FOXA1 mutations reveal distinct chromatin profiles and influence therapeutic response in breast cancer
A Arruabarrena-Aristorena, JLV Maag, S Kittane, Y Cai, WR Karthaus, ...
Cancer cell 38 (4), 534-550. e9, 2020
752020
Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2)
E Cocco, F Javier Carmona, P Razavi, HH Won, Y Cai, V Rossi, C Chan, ...
Science signaling 11 (551), eaat9773, 2018
702018
TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors
E Cocco, JE Lee, S Kannan, AM Schram, HH Won, S Shifman, A Kulick, ...
Cancer discovery 11 (1), 126-141, 2021
382021
Phase and context shape the function of composite oncogenic mutations
AN Gorelick, FJ Sánchez-Rivera, Y Cai, CM Bielski, E Biederstedt, ...
Nature 582 (7810), 100-103, 2020
382020
Genomic Alterations in PIK3CA-Mutated Breast Cancer Result in mTORC1 Activation and Limit the Sensitivity to PI3Kα Inhibitors
Y Cai, G Xu, F Wu, F Michelini, C Chan, X Qu, P Selenica, E Ladewig, ...
Cancer research 81 (9), 2470-2480, 2021
232021
The X protein of hepatitis B virus activates hepatoma cell proliferation through repressing melanoma inhibitory activity 2 gene
Y Xu, Y Yang, Y Cai, F Liu, Y Liu, Y Zhu, J Wu
Biochemical and Biophysical Research Communications 416 (3-4), 379-384, 2011
222011
HERP binds TBK1 to activate innate immunity and repress virus replication in response to endoplasmic reticulum stress
M Ge, Z Luo, Z Qiao, Y Zhou, X Cheng, Q Geng, Y Cai, P Wan, Y Xiong, ...
The Journal of Immunology 199 (9), 3280-3292, 2017
202017
HER2-mediated internalization of cytotoxic agents in ERBB2 amplified or mutant lung cancers. Cancer Discov. 2020; 10: 674–687. doi: 10.1158/2159-8290
BT Li, F Michelini, S Misale, E Cocco, L Baldino, Y Cai, S Shifman, HY Tu, ...
CD-20-0215.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
20
Cancer-associated chromosomal deletions: Size makes a difference
Y Cai, AA Sablina
Cell Cycle 15 (21), 2850-2851, 2016
82016
ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance
A Strillacci, P Sansone, VK Rajasekhar, M Turkekul, V Boyko, F Meng, ...
NPJ Breast Cancer 8 (1), 96, 2022
72022
NR2F2 mediates cell growth and endocrine resistance in NF1 loss, ER+ breast cancer
Y Cai, P Zhao, F Wu, H Shao, P Razavi, G Xu, M Scaltriti, ...
Cancer Research 82 (12_Supplement), 1778-1778, 2022
2022
PROGNOSIS-LINKED FOXA1 MUTATIONS ALTER DNA BINDING AND TRANSCRIPTION
A Arruabarrena-Aristorena, JL Maag, S Kittane, Y Cai, WR Karthaus, ...
CANCER DISCOVERY 10 (11), 1622-1622, 2020
2020
Abstract A14: Mutations in the ubiquitin ligase adaptor LZTR1 drive human disease by dysregulating RAS ubiquitination and signaling
M Steklov, S Pandolfi, MF Baietti, P Carai, M Zhang, H Jang, Y Cai, ...
Molecular Cancer Research 18 (5_Supplement), A14-A14, 2020
2020
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