The genomic landscape of endocrine-resistant advanced breast cancers P Razavi, MT Chang, G Xu, C Bandlamudi, DS Ross, N Vasan, Y Cai, ... Cancer cell 34 (3), 427-438. e6, 2018 | 801 | 2018 |
HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers BT Li, F Michelini, S Misale, E Cocco, L Baldino, Y Cai, S Shifman, HY Tu, ... Cancer discovery 10 (5), 674-687, 2020 | 177 | 2020 |
Loss of chromosome 8p governs tumor progression and drug response by altering lipid metabolism Y Cai, J Crowther, T Pastor, LA Asbagh, MF Baietti, M De Troyer, ... Cancer cell 29 (5), 751-766, 2016 | 176 | 2016 |
Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination M Steklov, S Pandolfi, MF Baietti, A Batiuk, P Carai, P Najm, M Zhang, ... Science 362 (6419), 1177-1182, 2018 | 153 | 2018 |
ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer G Xu, S Chhangawala, E Cocco, P Razavi, Y Cai, JE Otto, L Ferrando, ... Nature genetics 52 (2), 198-207, 2020 | 152 | 2020 |
Efficacy and Determinants of Response to HER Kinase Inhibition in HER2-Mutant Metastatic Breast Cancer LM Smyth, SA Piha-Paul, HH Won, AM Schram, C Saura, S Loi, J Lu, ... Cancer discovery 10 (2), 198-213, 2020 | 107 | 2020 |
Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones D Liang, Y Feng, F Zandkarimi, H Wang, Z Zhang, J Kim, Y Cai, W Gu, ... Cell 186 (13), 2748-2764. e22, 2023 | 83 | 2023 |
FOXA1 mutations reveal distinct chromatin profiles and influence therapeutic response in breast cancer A Arruabarrena-Aristorena, JLV Maag, S Kittane, Y Cai, WR Karthaus, ... Cancer cell 38 (4), 534-550. e9, 2020 | 75 | 2020 |
Neratinib is effective in breast tumors bearing both amplification and mutation of ERBB2 (HER2) E Cocco, F Javier Carmona, P Razavi, HH Won, Y Cai, V Rossi, C Chan, ... Science signaling 11 (551), eaat9773, 2018 | 70 | 2018 |
TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors E Cocco, JE Lee, S Kannan, AM Schram, HH Won, S Shifman, A Kulick, ... Cancer discovery 11 (1), 126-141, 2021 | 38 | 2021 |
Phase and context shape the function of composite oncogenic mutations AN Gorelick, FJ Sánchez-Rivera, Y Cai, CM Bielski, E Biederstedt, ... Nature 582 (7810), 100-103, 2020 | 38 | 2020 |
Genomic Alterations in PIK3CA-Mutated Breast Cancer Result in mTORC1 Activation and Limit the Sensitivity to PI3Kα Inhibitors Y Cai, G Xu, F Wu, F Michelini, C Chan, X Qu, P Selenica, E Ladewig, ... Cancer research 81 (9), 2470-2480, 2021 | 23 | 2021 |
The X protein of hepatitis B virus activates hepatoma cell proliferation through repressing melanoma inhibitory activity 2 gene Y Xu, Y Yang, Y Cai, F Liu, Y Liu, Y Zhu, J Wu Biochemical and Biophysical Research Communications 416 (3-4), 379-384, 2011 | 22 | 2011 |
HERP binds TBK1 to activate innate immunity and repress virus replication in response to endoplasmic reticulum stress M Ge, Z Luo, Z Qiao, Y Zhou, X Cheng, Q Geng, Y Cai, P Wan, Y Xiong, ... The Journal of Immunology 199 (9), 3280-3292, 2017 | 20 | 2017 |
HER2-mediated internalization of cytotoxic agents in ERBB2 amplified or mutant lung cancers. Cancer Discov. 2020; 10: 674–687. doi: 10.1158/2159-8290 BT Li, F Michelini, S Misale, E Cocco, L Baldino, Y Cai, S Shifman, HY Tu, ... CD-20-0215.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 20 | |
Cancer-associated chromosomal deletions: Size makes a difference Y Cai, AA Sablina Cell Cycle 15 (21), 2850-2851, 2016 | 8 | 2016 |
ERα-LBD, an isoform of estrogen receptor alpha, promotes breast cancer proliferation and endocrine resistance A Strillacci, P Sansone, VK Rajasekhar, M Turkekul, V Boyko, F Meng, ... NPJ Breast Cancer 8 (1), 96, 2022 | 7 | 2022 |
NR2F2 mediates cell growth and endocrine resistance in NF1 loss, ER+ breast cancer Y Cai, P Zhao, F Wu, H Shao, P Razavi, G Xu, M Scaltriti, ... Cancer Research 82 (12_Supplement), 1778-1778, 2022 | | 2022 |
PROGNOSIS-LINKED FOXA1 MUTATIONS ALTER DNA BINDING AND TRANSCRIPTION A Arruabarrena-Aristorena, JL Maag, S Kittane, Y Cai, WR Karthaus, ... CANCER DISCOVERY 10 (11), 1622-1622, 2020 | | 2020 |
Abstract A14: Mutations in the ubiquitin ligase adaptor LZTR1 drive human disease by dysregulating RAS ubiquitination and signaling M Steklov, S Pandolfi, MF Baietti, P Carai, M Zhang, H Jang, Y Cai, ... Molecular Cancer Research 18 (5_Supplement), A14-A14, 2020 | | 2020 |