M1 macrophage exosomes engineered to foster M1 polarization and target the IL-4 receptor inhibit tumor growth by reprogramming tumor-associated macrophages into M1-like macrophages GR Gunassekaran, SMP Vadevoo, MC Baek, B Lee Biomaterials 278, 121137, 2021 | 197 | 2021 |
Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A EJ Im, CH Lee, PG Moon, GG Rangaswamy, B Lee, JM Lee, JC Lee, ... Nature communications 10 (1), 1387, 2019 | 158 | 2019 |
Ursolic acid attenuates oxidative stress-mediated hepatocellular carcinoma induction by diethylnitrosamine in male Wistar rats R Gayathri, DK Priya, GR Gunassekaran, D Sakthisekaran Asian Pac J Cancer Prev 10 (5), 933-938, 2009 | 107 | 2009 |
The macrophage odorant receptor Olfr78 mediates the lactate-induced M2 phenotype of tumor-associated macrophages SMP Vadevoo, GR Gunassekaran, CE Lee, NH Lee, J Lee, S Chae, ... Proceedings of the National Academy of Sciences 118 (37), e2102434118, 2021 | 65 | 2021 |
Phage display-identified PD-L1-binding peptides reinvigorate T-cell activity and inhibit tumor progression S Gurung, F Khan, GR Gunassekaran, J Do Yoo, SMP Vadevoo, ... Biomaterials 247, 119984, 2020 | 45 | 2020 |
Double-chambered ferritin platform: dual-function payloads of cytotoxic peptides and fluorescent protein S Kim, GS Kim, J Seo, G Gowri Rangaswamy, IS So, RW Park, BH Lee, ... Biomacromolecules 17 (1), 12-19, 2016 | 40 | 2016 |
A peptide probe enables photoacoustic-guided imaging and drug delivery to lung tumors in K-rasLA2 mutant mice H Jung, S Park, GR Gunassekaran, M Jeon, YE Cho, MC Baek, JY Park, ... Cancer research 79 (16), 4271-4282, 2019 | 39 | 2019 |
Interleukin-4 receptor-targeted delivery of Bcl-xL siRNA sensitizes tumors to chemotherapy and inhibits tumor growth P Guruprasath, J Kim, GR Gunassekaran, L Chi, S Kim, RW Park, SH Kim, ... Biomaterials 142, 101-111, 2017 | 36 | 2017 |
Peptide-based targeted therapeutics and apoptosis imaging probes for cancer therapy SMP Vadevoo, S Gurung, F Khan, ME Haque, GR Gunassekaran, L Chi, ... Archives of pharmacal research 42, 150-158, 2019 | 33 | 2019 |
IL4 Receptor–Targeted Proapoptotic Peptide Blocks Tumor Growth and Metastasis by Enhancing Antitumor Immunity SMP Vadevoo, JE Kim, GR Gunassekaran, HK Jung, L Chi, DE Kim, ... Molecular Cancer Therapeutics 16 (12), 2803-2816, 2017 | 31 | 2017 |
Apoptotic role of natural isothiocyanate from broccoli (Brassica oleracea italica) in experimental chemical lung carcinogenesis D Kalpana Deepa Priya, R Gayathri, GR Gunassekaran, S Murugan, ... Pharmaceutical Biology 51 (5), 621-628, 2013 | 27 | 2013 |
Protective role of sulforaphane against oxidative stress mediated mitochondrial dysfunction induced by benzo (a) pyrene in female Swiss albino mice DKD Priya, R Gayathri, GR Gunassekaran, D Sakthisekaran Pulmonary pharmacology & therapeutics 24 (1), 110-117, 2011 | 26 | 2011 |
Peptides as multifunctional players in cancer therapy SMP Vadevoo, S Gurung, HS Lee, GR Gunassekaran, SM Lee, JW Yoon, ... Experimental & Molecular Medicine 55 (6), 1099-1109, 2023 | 25 | 2023 |
Identification of novel CD44v6-binding peptides that block CD44v6 and deliver a pro-apoptotic peptide to tumors to inhibit tumor growth and metastasis in mice F Khan, S Gurung, GR Gunassekaran, SMP Vadevoo, L Chi, U Permpoon, ... Theranostics 11 (3), 1326, 2021 | 21 | 2021 |
In vitro and in vivo studies on antitumor effects of gossypol on human stomach adenocarcinoma (AGS) cell line and MNNG induced experimental gastric cancer GR Gunassekaran, DKD Priya, R Gayathri, D Sakthisekaran Biochemical and Biophysical Research Communications 411 (4), 661-666, 2011 | 21 | 2011 |
Chemopreventive role of sulforaphane by upholding the GSH redox cycle in pre-and post-initiation phases of experimental lung carcinogenesis DK Priya, R Gayathri, GR Gunassekaran, S Murugan, D Sakthisekaran Asian Pac J Cancer Prev 12 (1), 103-10, 2011 | 21 | 2011 |
Protective role of ursolic acid in den induced oxidative stress mediated hepatocellular carcinoma a focus on thiol status R Gayathri, D Kalpana, GR Gunassekaran, S Dhanapal Int J Pharm Pharm Sci 2 (4), 140-6, 2010 | 18 | 2010 |
Non-genetic engineering of cytotoxic T cells to target IL-4 receptor enhances tumor homing and therapeutic efficacy against melanoma GR Gunassekaran, CM Hong, SMP Vadevoo, L Chi, P Guruprasath, ... Biomaterials 159, 161-173, 2018 | 16 | 2018 |
Inhibitory effect of sulforaphane against benzo (a) pyrene induced lung cancer by modulation of biochemical signatures in female Swiss albino mice. DKD Priya, R Gayathri, GR Gunassekaran, S Murugan, D Sakthisekaran Asian Journal of Biochemistry 6 (5), 395-405, 2011 | 13 | 2011 |
Protective role of gossypol against N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) induced gastric carcinogenesis in experimental rats GR Gunassekaran, R Gayathri, DKD Priya, S Murugan, D Sakithsekaran International Journal of Medicine and Medical Sciences 2 (4), 121-127, 2010 | 12 | 2010 |