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brian james
brian james
Director Genomics Core, Sanford Burnham Prebys Medical Discovery Institute
Verified email at sbpdiscovery.org
Title
Cited by
Cited by
Year
Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer
S Kopetz, J Desai, E Chan, JR Hecht, PJ O'Dwyer, D Maru, V Morris, ...
Journal of clinical oncology 33 (34), 4032-4038, 2015
7722015
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2
J Shen, W Xia, YB Khotskaya, L Huo, K Nakanishi, SO Lim, Y Du, Y Wang, ...
Nature 497 (7449), 383-387, 2013
4442013
Hypoxia triggers hedgehog-mediated tumor–stromal interactions in pancreatic cancer
TR Spivak-Kroizman, G Hostetter, R Posner, M Aziz, C Hu, MJ Demeure, ...
Cancer research 73 (11), 3235-3247, 2013
2232013
Ets2 mediated tumor suppressive function and met oncogene inhibition in human non–small cell lung cancer
M Kabbout, MM Garcia, J Fujimoto, DD Liu, D Woods, CW Chow, ...
Clinical cancer research 19 (13), 3383-3395, 2013
1682013
Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer
MV Recouvreux, MR Moldenhauer, KMO Galenkamp, M Jung, B James, ...
Journal of Experimental Medicine 217 (9), 2020
1412020
Definition of a novel feed-forward mechanism for glycolysis-HIF1α signaling in hypoxic tumors highlights aldolase A as a therapeutic target
G Grandjean, PR de Jong, BP James, MY Koh, R Lemos, J Kingston, ...
Cancer research 76 (14), 4259-4269, 2016
752016
Identification of thioredoxin-interacting protein 1 as a hypoxia-inducible factor 1α-induced gene in pancreatic cancer
AF Baker, MY Koh, RR Williams, B James, H Wang, WR Tate, A Gallegos, ...
Pancreas 36 (2), 178-186, 2008
712008
SARS-CoV-2 ORF9c is a membrane-associated protein that suppresses antiviral responses in cells
A Dominguez Andres, Y Feng, AR Campos, J Yin, CC Yang, B James, ...
BioRxiv, 2020.08. 18.256776, 2020
692020
Expression profiling stratifies mesothelioma tumors and signifies deregulation of spindle checkpoint pathway and microtubule network with therapeutic implications
MB Suraokar, MI Nunez, L Diao, CW Chow, D Kim, C Behrens, H Lin, ...
Annals of oncology 25 (6), 1184-1192, 2014
622014
Regulation of S100A8 stability by RNF5 in intestinal epithelial cells determines intestinal inflammation and severity of colitis
YU Fujita, A Khateb, Y Li, R Tinoco, T Zhang, H Bar-Yoseph, MA Tam, ...
Cell reports 24 (12), 3296-3311. e6, 2018
582018
SBI-0640756 attenuates the growth of clinically unresponsive melanomas by disrupting the eIF4F translation initiation complex
Y Feng, AB Pinkerton, L Hulea, T Zhang, MA Davies, S Grotegut, Y Cheli, ...
Cancer research 75 (24), 5211-5218, 2015
432015
Nuclear Localization of the ERK MAP Kinase Mediated by Drosophila αPS2βPS Integrin and Importin-7
BP James, TA Bunch, S Krishnamoorthy, LA Perkins, DL Brower
Molecular biology of the cell 18 (10), 4190-4199, 2007
402007
Absence of HIF1A leads to glycogen accumulation and an inflammatory response that enables pancreatic tumor growth
M Maruggi, FI Layng, R Lemos Jr, G Garcia, BP James, M Sevilla, ...
Cancer research 79 (22), 5839-5848, 2019
312019
Identification and characterization of IMD-0354 as a glutamine carrier protein inhibitor in melanoma
Y Feng, G Pathria, S Heynen-Genel, M Jackson, B James, J Yin, DA Scott, ...
Molecular cancer therapeutics 20 (5), 816-832, 2021
282021
A myelin basic protein fragment induces sexually dimorphic transcriptome signatures of neuropathic pain in mice
AV Chernov, SK Hullugundi, KA Eddinger, J Dolkas, AG Remacle, ...
Journal of Biological Chemistry 295 (31), 10807-10821, 2020
242020
IL-6 contributes to metastatic switch via the differentiation of monocytic-dendritic progenitors into prometastatic immune cells
K Magidey-Klein, TJ Cooper, K Kveler, R Normand, T Zhang, M Timaner, ...
Journal for immunotherapy of cancer 9 (6), 2021
232021
Superoxide dismutase is regulated by LAMMER kinase in Drosophila and human cells
BP James, WD Staatz, ST Wilkinson, E Meuillet, G Powis
Free Radical Biology and Medicine 46 (6), 821-827, 2009
212009
SPANX control of lamin A/C modulates nuclear architecture and promotes melanoma growth
I Lazar, B Fabre, Y Feng, A Khateb, P Turko, JM Martinez Gomez, ...
Molecular Cancer Research 18 (10), 1560-1573, 2020
172020
Neural network recognition of signal modulation types
G Hagedorn, B James, C Miller
Proc. ANNIEC, 170-175, 1997
171997
A transcriptionally inactive ATF2 variant drives melanomagenesis
G Claps, Y Cheli, T Zhang, M Scortegagna, E Lau, H Kim, J Qi, JL Li, ...
Cell reports 15 (9), 1884-1892, 2016
142016
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