Rana Moubarak
Rana Moubarak
NYU Langone Medical Center
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Sequential activation of poly (ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis
RS Moubarak, VJ Yuste, C Artus, A Bouharrour, PA Greer, ...
Molecular and cellular biology 27 (13), 4844-4862, 2007
Epigenetic silencing of CDR1as drives IGF2BP3-mediated melanoma invasion and metastasis
D Hanniford, A Ulloa-Morales, A Karz, MG Berzoti-Coelho, RS Moubarak, ...
Cancer cell 37 (1), 55-70. e15, 2020
Cysteine protease inhibition prevents mitochondrial apoptosis-inducing factor (AIF) release
VJ Yuste, RS Moubarak, C Delettre, M Bras, P Sancho, N Robert, ...
Cell Death & Differentiation 12 (11), 1445-1448, 2005
FBXW7 modulates cellular stress response and metastatic potential through HSF1 post-translational modification
N Kourtis, RS Moubarak, B Aranda-Orgilles, K Lui, IT Aydin, T Trimarchi, ...
Nature cell biology 17 (3), 322-332, 2015
The contribution of apoptosis-inducing factor, caspase-activated DNase, and inhibitor of caspase-activated DNase to the nuclear phenotype and DNA degradation during apoptosis
VJ Yuste, I Sánchez-López, C Solé, RS Moubarak, JR Bayascas, X Dolcet, ...
Journal of Biological Chemistry 280 (42), 35670-35683, 2005
AIFsh, a novel apoptosis-inducing factor (AIF) pro-apoptotic isoform with potential pathological relevance in human cancer
C Delettre, VJ Yuste, RS Moubarak, M Bras, JC Lesbordes-Brion, ...
Journal of biological chemistry 281 (10), 6413-6427, 2006
The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis
MF Segura, C Sole, M Pascual, RS Moubarak, MJ Perez-Garcia, ...
Journal of Neuroscience 27 (42), 11228-11241, 2007
BRG1/SMARCA4 is essential for neuroblastoma cell viability through modulation of cell death and survival pathways
L Jubierre, A Soriano, L Planells-Ferrer, L París-Coderch, SP Tenbaum, ...
Oncogene 35 (39), 5179-5190, 2016
Identification and characterization of AIFsh2, a mitochondrial apoptosis-inducing factor (AIF) isoform with NADH oxidase activity
C Delettre, VJ Yuste, RS Moubarak, M Bras, N Robert, SA Susin
Journal of Biological Chemistry 281 (27), 18507-18518, 2006
TNFα induces survival through the FLIP-L-dependent activation of the MAPK/ERK pathway
F Marques-Fernandez, L Planells-Ferrer, R Gozzelino, KMO Galenkamp, ...
Cell death & disease 4 (2), e493-e493, 2013
CD44 ligation induces caspase-independent cell death via a novel calpain/AIF pathway in human erythroleukemia cells
C Artus, E Maquarre, RS Moubarak, C Delettre, C Jasmin, SA Susin, ...
Oncogene 25 (42), 5741-5751, 2006
A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease
Q Sun, W Lee, Y Mohri, M Takeo, CH Lim, X Xu, P Myung, RP Atit, ...
Nature communications 10 (1), 5023, 2019
BCL-XL regulates TNF-α-mediated cell death independently of NF-κB, FLIP and IAPs
R Gozzelino, C Sole, N Llecha, MF Segura, RS Moubarak, ...
Cell research 18 (10), 1020-1036, 2008
Amyloid-β reduces the expression of neuronal FAIM-L, thereby shifting the inflammatory response mediated by TNFα from neuronal protection to death
P Carriba, S Jimenez, V Navarro, I Moreno-Gonzalez, ...
Cell death & disease 6 (2), e1639-e1639, 2015
TNFα sensitizes neuroblastoma cells to FasL-, cisplatin-and etoposide-induced cell death by NF-κB-mediated expression of Fas
KMO Galenkamp, P Carriba, J Urresti, L Planells-Ferrer, E Coccia, ...
Molecular cancer 14, 1-14, 2015
A role for the tyrosine kinase ACK1 in neurotrophin signaling and neuronal extension and branching
A La Torre, M del Mar Masdeu, T Cotrufo, RS Moubarak, JA Del Río, ...
Cell death & disease 4 (4), e602-e602, 2013
FAIM-L is an IAP-binding protein that inhibits XIAP ubiquitinylation and protects from Fas-induced apoptosis
RS Moubarak, L Planells-Ferrer, J Urresti, S Reix, MF Segura, P Carriba, ...
Journal of Neuroscience 33 (49), 19262-19275, 2013
Lifeguard inhibits Fas ligand-mediated endoplasmic reticulum-calcium release mandatory for apoptosis in type II apoptotic cells
J Urresti, M Ruiz-Meana, E Coccia, JC Arévalo, J Castellano, ...
Journal of Biological Chemistry 291 (3), 1221-1234, 2016
A pathway involving HDAC5, cFLIP and caspases regulates expression of the splicing regulator polypyrimidine tract binding protein in the heart
J Ye, M Llorian, M Cardona, A Rongvaux, RS Moubarak, JX Comella, ...
Journal of Cell Science 126 (7), 1682-1691, 2013
MYCN repression of Lifeguard/FAIM2 enhances neuroblastoma aggressiveness
L Planells-Ferrer, J Urresti, A Soriano, S Reix, DM Murphy, JC Ferreres, ...
Cell death & disease 5 (9), e1401-e1401, 2014
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