Site-directed conjugation of “clicked” glycopolymers to form glycoprotein mimics: binding to mammalian lectin and induction of immunological function J Geng, G Mantovani, L Tao, J Nicolas, G Chen, R Wallis, DA Mitchell, ... Journal of the American Chemical Society 129 (49), 15156-15163, 2007 | 341 | 2007 |
Simultaneous activation of complement and coagulation by MBL-associated serine protease 2 A Krarup, R Wallis, JS Presanis, P Gál, RB Sim PloS one 2 (7), e623, 2007 | 327 | 2007 |
Targeting of mannan-binding lectin-associated serine protease-2 confers protection from myocardial and gastrointestinal ischemia/reperfusion injury WJ Schwaeble, NJ Lynch, JE Clark, M Marber, NJ Samani, YM Ali, ... Proceedings of the National Academy of Sciences 108 (18), 7523-7528, 2011 | 256 | 2011 |
Paths reunited: Initiation of the classical and lectin pathways of complement activation R Wallis, DA Mitchell, R Schmid, WJ Schwaeble, AH Keeble Immunobiology 215 (1), 1-11, 2010 | 248 | 2010 |
Sequence-controlled multi-block glycopolymers to inhibit DC-SIGN-gp120 binding Q Zhang, J Collins, A Anastasaki, R Wallis, DA Mitchell, CR Becer, ... Angewandte Chemie International Edition 52 (16), 4435-4439, 2013 | 246 | 2013 |
The hemopexin and O-glycosylated domains tune gelatinase B/MMP-9 bioavailability via inhibition and binding to cargo receptors PE Van den Steen, I Van Aelst, V Hvidberg, H Piccard, P Fiten, ... Journal of Biological Chemistry 281 (27), 18626-18637, 2006 | 218 | 2006 |
The lectin pathway of complement activation is a critical component of the innate immune response to pneumococcal infection YM Ali, NJ Lynch, KS Haleem, T Fujita, Y Endo, S Hansen, U Holmskov, ... PLoS pathogens 8 (7), e1002793, 2012 | 211 | 2012 |
High-affinity glycopolymer binding to human DC-SIGN and disruption of DC-SIGN interactions with HIV envelope glycoprotein CR Becer, MI Gibson, J Geng, R Ilyas, R Wallis, DA Mitchell, ... Journal of the American Chemical Society 132 (43), 15130-15132, 2010 | 211 | 2010 |
Two mechanisms for mannose-binding protein modulation of the activity of its associated serine proteases CB Chen, R Wallis Journal of Biological Chemistry 279 (25), 26058-26065, 2004 | 193 | 2004 |
Protein-protein interactions in colicin E9 DNase-immunity protein complexes. 1. Diffusion-controlled association and femtomolar binding for the cognate complex R Wallis, GR Moore, R James, C Kleanthous Biochemistry 34 (42), 13743-13750, 1995 | 188 | 1995 |
Stoichiometry of complexes between mannose-binding protein and its associated serine proteases: defining functional units for complement activation CB Chen, R Wallis Journal of Biological Chemistry 276 (28), 25894-25902, 2001 | 181 | 2001 |
Interactions between mannose-binding lectin and MASPs during complement activation by the lectin pathway R Wallis Immunobiology 212 (4-5), 289-299, 2007 | 175 | 2007 |
Dendritic cell lectin-targeting sentinel-like unimolecular glycoconjugates to release an anti-HIV drug Q Zhang, L Su, J Collins, G Chen, R Wallis, DA Mitchell, DM Haddleton, ... Journal of the American Chemical Society 136 (11), 4325-4332, 2014 | 160 | 2014 |
Crystal structure of the CUB1‐EGF‐CUB2 region of mannose‐binding protein associated serine protease‐2 H Feinberg, JCM Uitdehaag, JM Davies, R Wallis, K Drickamer, WI Weis The EMBO journal, 2003 | 160 | 2003 |
Interaction of mannose-binding protein with associated serine proteases: effects of naturally occurring mutations R Wallis, RB Dodd Journal of Biological Chemistry 275 (40), 30962-30969, 2000 | 155 | 2000 |
Molecular determinants of oligomer formation and complement fixation in mannose-binding proteins R Wallis, K Drickamer Journal of Biological Chemistry 274 (6), 3580-3589, 1999 | 155 | 1999 |
Localization of the serine protease-binding sites in the collagen-like domain of mannose-binding protein: indirect effects of naturally occurring mutations on protease binding … R Wallis, JM Shaw, J Uitdehaag, CB Chen, D Torgersen, K Drickamer Journal of Biological Chemistry 279 (14), 14065-14073, 2004 | 133 | 2004 |
Rationale for targeting complement in COVID‐19 A Polycarpou, M Howard, CA Farrar, R Greenlaw, G Fanelli, R Wallis, ... EMBO molecular medicine 12 (8), e12642, 2020 | 130 | 2020 |
Characterization and Membrane Assembly of the TatA Component of the Escherichia coli Twin-Arginine Protein Transport System I Porcelli, E de Leeuw, R Wallis, E van den Brink-van der Laan, ... Biochemistry 41 (46), 13690-13697, 2002 | 129 | 2002 |
Conformational changes in the AAA ATPase p97–p47 adaptor complex F Beuron, I Dreveny, X Yuan, VE Pye, C Mckeown, LC Briggs, MJ Cliff, ... The EMBO journal 25 (9), 1967-1976, 2006 | 126 | 2006 |