Cellular and molecular identity of tumor-associated macrophages in glioblastoma Z Chen, X Feng, CJ Herting, VA Garcia, K Nie, WW Pong, R Rasmussen, ... Cancer research 77 (9), 2266-2278, 2017 | 556 | 2017 |
IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response FJ Núñez, FM Mendez, P Kadiyala, MS Alghamri, MG Savelieff, ... Science translational medicine 11 (479), eaaq1427, 2019 | 212 | 2019 |
Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors I Kaffes, F Szulzewsky, Z Chen, CJ Herting, B Gabanic, ... Oncoimmunology 8 (11), e1655360, 2019 | 89 | 2019 |
Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma V Maximov, Z Chen, Y Wei, MH Robinson, CJ Herting, NS Shanmugam, ... Nature communications 10 (1), 2410, 2019 | 87 | 2019 |
Genetic driver mutations define the expression signature and microenvironmental composition of high‐grade gliomas CJ Herting, Z Chen, KL Pitter, F Szulzewsky, I Kaffes, M Kaluzova, ... Glia 65 (12), 1914-1926, 2017 | 62 | 2017 |
Tumour-associated macrophage-derived interleukin-1 mediates glioblastoma-associated cerebral oedema CJ Herting, Z Chen, V Maximov, A Duffy, F Szulzewsky, ... Brain 142 (12), 3834-3851, 2019 | 60 | 2019 |
Iridium (III)-bis (imidazolinyl) phenyl catalysts for enantioselective C–H functionalization with ethyl diazoacetate NM Weldy, AG Schafer, CP Owens, CJ Herting, A Varela-Alvarez, S Chen, ... Chemical Science 7 (5), 3142-3146, 2016 | 56 | 2016 |
Platelet-derived growth factor beta is a potent inflammatory driver in paediatric high-grade glioma JL Ross, Z Chen, CJ Herting, Y Grabovska, F Szulzewsky, M Puigdelloses, ... Brain 144 (1), 53-69, 2021 | 48 | 2021 |
The tumor microenvironment in pancreatic ductal adenocarcinoma: current perspectives and future directions CJ Herting, I Karpovsky, GB Lesinski Cancer and Metastasis Reviews, 1-15, 2021 | 37 | 2021 |
Genetic driver mutations introduced in identical cell‐of‐origin in murine glioblastoma reveal distinct immune landscapes but similar response to checkpoint blockade Z Chen, CJ Herting, JL Ross, B Gabanic, M Puigdelloses Vallcorba, ... Glia 68 (10), 2148-2166, 2020 | 32 | 2020 |
Macropinocytosis of bevacizumab by glioblastoma cells in the perivascular niche affects their survival G Müller-Greven, CR Carlin, ME Burgett, MS Ahluwalia, A Lauko, ... Clinical Cancer Research 23 (22), 7059-7071, 2017 | 25 | 2017 |
Chromodomain helicase DNA-binding protein 7 is suppressed in the perinecrotic/ischemic microenvironment and is a novel regulator of glioblastoma angiogenesis NH Boyd, K Walker, A Ayokanmbi, ER Gordon, J Whetsel, CM Smith, ... Stem Cells 37 (4), 453-462, 2019 | 22 | 2019 |
A multi-center, single-arm, phase Ib study of pembrolizumab (MK-3475) in combination with chemotherapy for patients with advanced colorectal cancer: HCRN GI14-186 CJ Herting, MR Farren, Y Tong, Z Liu, B O’Neil, T Bekaii-Saab, A Noonan, ... Cancer Immunology, Immunotherapy 70 (11), 3337-3348, 2021 | 17 | 2021 |
A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives genotype-dependent glioblastoma progression Z Chen, B Giotti, M Kaluzova, MP Vallcorba, K Rawat, G Price, CJ Herting, ... The Journal of Clinical Investigation 133 (22), 2023 | 6 | 2023 |
Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell–and CXCR3-dependent manner MB Ware, M Phillips, C McQuinn, MY Zaidi, HM Knochelmann, E Greene, ... JCI insight 8 (8), 2023 | 6 | 2023 |
A paracrine circuit of IL-1β/IL-1R1 between myeloid and tumor cells drives glioblastoma progression Z Chen, B Giotti, M Kaluzova, CJ Herting, G Pinero, MP Vallcorba, ... BioRxiv, 2022.04. 03.486888, 2022 | 5 | 2022 |
Anti-EGFR antibodies in the management of advanced colorectal cancer PM Kasi, MG Afable, C Herting, M Lukanowski, Z Jin The Oncologist 28 (12), 1034-1048, 2023 | 4 | 2023 |
Phase Ib/II trial of siltuximab and spartalizumab in patients in metastatic pancreatic cancer. M Akce, WL Shaib, M Diab, OB Alese, C Wu, S Thomas, E Greene, ... Journal of Clinical Oncology 40 (4_suppl), TPS626-TPS626, 2022 | 4 | 2022 |
Clinically relevant orthotopic pancreatic cancer models for adoptive T cell transfer therapy NK Horvat, I Karpovsky, M Phillips, MM Wyatt, MA Hall, CJ Herting, ... Journal for Immunotherapy of Cancer 12 (1), 2024 | 1 | 2024 |
High-risk Gene Expression in Colorectal Liver Metastases: Potential for Novel Therapies CR Medin, M Turgeon, J Keilson, B Dwivedi, C Herting, S Maithel, ... ANNALS OF SURGICAL ONCOLOGY 29 (SUPPL 2), 381-381, 2022 | 1 | 2022 |