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Jian Shen
Jian Shen
Northwestern University
Verified email at mcw.edu
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Year
BATF regulates progenitor to cytolytic effector CD8+ T cell transition during chronic viral infection
Y Chen, RA Zander, X Wu, DM Schauder, MY Kasmani, J Shen, S Zheng, ...
Nature immunology 22 (8), 996-1007, 2021
902021
Tfh-cell-derived interleukin 21 sustains effector CD8+ T cell responses during chronic viral infection
R Zander, MY Kasmani, Y Chen, P Topchyan, J Shen, S Zheng, R Burns, ...
Immunity 55 (3), 475-493. e5, 2022
622022
Single-cell lineage mapping of a diverse virus-specific naive CD4 T cell repertoire
A Khatun, MY Kasmani, R Zander, DM Schauder, JP Snook, J Shen, X Wu, ...
Journal of Experimental Medicine 218 (3), 2021
502021
The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
S Lukhele, D Abd Rabbo, M Guo, J Shen, HJ Elsaesser, R Quevedo, ...
Immunity 55 (12), 2369-2385. e10, 2022
382022
Critical role of Jumonji domain of JMJD1C in MLL-rearranged leukemia
J Izaguirre-Carbonell, L Christiansen, R Burns, J Schmitz, C Li, RL Mokry, ...
Blood advances 3 (9), 1499-1511, 2019
272019
Single-Cell Transcriptomics Reveals Core Regulatory Programs That Determine the Heterogeneity of Circulating and Tissue-Resident Memory CD8+ T Cells
Y Chen, J Shen, MY Kasmani, P Topchyan, W Cui
Cells 10 (8), 2143, 2021
262021
E2A-regulated epigenetic landscape promotes memory CD8 T cell differentiation
DM Schauder, J Shen, Y Chen, MY Kasmani, MR Kudek, R Burns, W Cui
Proceedings of the National Academy of Sciences 118 (16), e2013452118, 2021
232021
Harnessing the IL-21-BATF Pathway in the CD8+ T Cell Anti-Tumor Response
P Topchyan, G Xin, Y Chen, S Zheng, R Burns, J Shen, MY Kasmani, ...
Cancers 13 (6), 1263, 2021
202021
Pathogen-boosted adoptive cell transfer therapy induces endogenous antitumor immunity through antigen spreading
G Xin, A Khatun, P Topchyan, R Zander, PJ Volberding, Y Chen, J Shen, ...
Cancer immunology research 8 (1), 7-18, 2020
202020
Loss of PBAF promotes expansion and effector differentiation of CD8+ T cells during chronic viral infection and cancer
A Kharel, J Shen, R Brown, Y Chen, C Nguyen, D Alson, T Bluemn, J Fan, ...
Cell reports 42 (6), 2023
62023
Bhlhe40 Promotes CD4+ T Helper 1 Cell and Suppresses T Follicular Helper Cell Differentiation during Viral Infection
C Nguyen, M Kudek, R Zander, H Niu, J Shen, A Bauer, D Alson, ...
The Journal of Immunology, 2024
2024
Mediator complex subunit 1 architects a tumorigenic Treg cell program independent of inflammation
SM Chaudhuri, SE Weinberg, D Wang, LK Yalom, E Montauti, R Iyer, ...
Cell Reports Medicine, 2024
2024
Releasing the TLE3 break to put TCM cells on a fast track
J Shen, S Lin, W Cui
Nature Immunology, 1-3, 2024
2024
PIM kinases are essential for CD8 T cell effector function and metabolism during chronic viral infection
AK Brown, J Shen, PJ Volberding, W Cui
The Journal of Immunology 210 (1_Supplement), 236.18-236.18, 2023
2023
Lymphocytic Choriomeningitis Virus Clone 13 Infection Results in CD8 T Cell–Mediated Host Mortality in Diacylglycerol Kinase α–Deficient Mice
MR Kudek, G Xin, D Alson, S Holzhauer, J Shen, MY Kasmani, M Riese, ...
The Journal of Immunology 210 (9), 1281-1291, 2023
2023
CD8 T Cells Mediate Host Death Following Lcmv Clone 13 Infection in Dgkα Deficiency
M Kudek, G Xin, SL Holzhauer, T Alson, J Shen, M Kasmani, M Riese, ...
Blood 140 (Supplement 1), 5504-5504, 2022
2022
Harnessing the IL-21-BATF Pathway in the CD8+ T Cell Anti-Tumor Response. Cancers 2021, 13, 1263
P Topchyan, G Xin, Y Chen, S Zheng, R Burns, J Shen, MY Kasmani, ...
s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021
2021
Mediator Complex Subunit 1 Promotes Differentiation and Function of a Tumor-Specific T Regulatory Cell Population
S Chaudhuri, S Weinberg, D Wang, LK Yalom, E Montauti, R Iyer, ...
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