Exogenous DNA loading into extracellular vesicles via electroporation is size-dependent and enables limited gene delivery TN Lamichhane, RS Raiker, SM Jay Molecular pharmaceutics 12 (10), 3650-3657, 2015 | 399 | 2015 |
Oncogene Knockdown via Active Loading of Small RNAs into Extracellular Vesicles by Sonication TN Lamichhane, A Jeyaram, DB Patel, B Parajuli, NK Livingston, ... Cellular and molecular bioengineering 9, 315-324, 2016 | 312 | 2016 |
Emerging roles for extracellular vesicles in tissue engineering and regenerative medicine TN Lamichhane, S Sokic, JS Schardt, RS Raiker, JW Lin, SM Jay Tissue Engineering Part B: Reviews 21 (1), 45-54, 2015 | 246 | 2015 |
Expanding the nucleotide repertoire of the ribosome with post-transcriptional modifications CS Chow, TN Lamichhane, SK Mahto ACS chemical biology 2 (9), 610-619, 2007 | 217 | 2007 |
Impact of cell culture parameters on production and vascularization bioactivity of mesenchymal stem cell‐derived extracellular vesicles DB Patel, KM Gray, Y Santharam, TN Lamichhane, KM Stroka, SM Jay Bioengineering & translational medicine 2 (2), 170-179, 2017 | 216 | 2017 |
3′ processing of eukaryotic precursor tRNAs RJ Maraia, TN Lamichhane Wiley Interdisciplinary Reviews: RNA 2 (3), 362-375, 2011 | 159 | 2011 |
Defective i6A37 Modification of Mitochondrial and Cytosolic tRNAs Results from Pathogenic Mutations in TRIT1 and Its Substrate tRNA JW Yarham, TN Lamichhane, A Pyle, S Mattijssen, E Baruffini, F Bruni, ... PLoS genetics 10 (6), e1004424, 2014 | 145 | 2014 |
Enhanced loading of functional miRNA cargo via pH gradient modification of extracellular vesicles A Jeyaram, TN Lamichhane, S Wang, L Zou, E Dahal, SM Kronstadt, ... Molecular Therapy 28 (3), 975-985, 2020 | 144 | 2020 |
RNA polymerase III output is functionally linked to tRNA dimethyl-G26 modification AG Arimbasseri, NH Blewett, JR Iben, TN Lamichhane, V Cherkasova, ... PLoS genetics 11 (12), e1005671, 2015 | 90 | 2015 |
Lack of tRNA modification isopentenyl-A37 alters mRNA decoding and causes metabolic deficiencies in fission yeast TN Lamichhane, NH Blewett, AK Crawford, VA Cherkasova, JR Iben, ... Molecular and cellular biology, 2013 | 83 | 2013 |
Ethanol induces enhanced vascularization bioactivity of endothelial cell-derived extracellular vesicles via regulation of microRNAs and long non-coding RNAs TN Lamichhane, CA Leung, LY Douti, SM Jay Scientific Reports 7 (1), 13794, 2017 | 64 | 2017 |
Human cells have a limited set of tRNA anticodon loop substrates of the tRNA isopentenyltransferase TRIT1 tumor suppressor TN Lamichhane, S Mattijssen, RJ Maraia Molecular and cellular biology 33 (24), 4900-4908, 2013 | 57 | 2013 |
Plasticity and diversity of tRNA anticodon determinants of substrate recognition by eukaryotic A37 isopentenyltransferases TN Lamichhane, NH Blewett, RJ Maraia Rna 17 (10), 1846-1857, 2011 | 53 | 2011 |
Production of extracellular vesicles loaded with therapeutic cargo TN Lamichhane, SM Jay Targeted Drug Delivery: Methods and Protocols, 37-47, 2018 | 51 | 2018 |
Selection of peptides targeting helix 31 of bacterial 16S ribosomal RNA by screening M13 phage-display libraries TN Lamichhane, ND Abeydeera, ACE Duc, PR Cunningham, CS Chow Molecules 16 (2), 1211-1239, 2011 | 38 | 2011 |
Lack of tRNA-i6A modification causes mitochondrial-like metabolic deficiency in S. pombe by limiting activity of cytosolic tRNATyr, not mito-tRNA TN Lamichhane, AG Arimbasseri, K Rijal, JR Iben, FY Wei, K Tomizawa, ... Rna 22 (4), 583-596, 2016 | 37 | 2016 |
Combined approaches to site-specific modification of RNA CS Chow, SK Mahto, TN Lamichhane ACS chemical biology 3 (1), 30-37, 2008 | 31 | 2008 |
Engineered multivalency enhances affibody-based HER3 inhibition and downregulation in cancer cells JS Schardt, JM Oubaid, SC Williams, JL Howard, CM Aloimonos, ... Molecular pharmaceutics 14 (4), 1047-1056, 2017 | 30 | 2017 |
Identification and role of functionally important motifs in the 970 loop of Escherichia coli 16S ribosomal RNA AA Saraiya, TN Lamichhane, CS Chow, J SantaLucia Jr, PR Cunningham Journal of molecular biology 376 (3), 645-657, 2008 | 27 | 2008 |
Protein–RNA dynamics in the central junction control 30S ribosome assembly KA Baker, R Lamichhane, T Lamichhane, D Rueda, PR Cunningham Journal of Molecular Biology 428 (18), 3615-3631, 2016 | 10 | 2016 |