A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses TK Tan, P Rijal, R Rahikainen, AH Keeble, L Schimanski, S Hussain, ... Nature communications 12 (1), 542, 2021 | 234 | 2021 |
Direct pharmacological targeting of a mitochondrial ion channel selectively kills tumor cells in vivo L Leanza, M Romio, KA Becker, M Azzolini, L Trentin, A Manago, ... Cancer cell 31 (4), 516-531. e10, 2017 | 150 | 2017 |
Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19 SP Graham, RK McLean, AJ Spencer, S Belij-Rammerstorfer, D Wright, ... NPJ vaccines 5 (1), 69, 2020 | 149 | 2020 |
Intrinsic and extrinsic mechanisms contribute to maintain the JAK/STAT pathway aberrantly activated in T-type large granular lymphocyte leukemia A Teramo, C Gattazzo, F Passeri, A Lico, G Tasca, A Cabrelle, V Martini, ... Blood, The Journal of the American Society of Hematology 121 (19), 3843-3854, 2013 | 118 | 2013 |
JAK/STAT/PKCδ molecular pathways in synovial fluid T lymphocytes reflect the in vivo T helper-17 expansion in psoriatic arthritis U Fiocco, B Accordi, V Martini, F Oliviero, M Facco, A Cabrelle, L Piva, ... Immunologic research 58, 61-69, 2014 | 76 | 2014 |
Cross-talk between chronic lymphocytic leukemia (CLL) tumor B cells and mesenchymal stromal cells (MSCs): implications for neoplastic cell survival V Trimarco, E Ave, M Facco, G Chiodin, F Frezzato, V Martini, C Gattazzo, ... Oncotarget 6 (39), 42130, 2015 | 53 | 2015 |
Enhanced chemokine receptor recycling and impaired S1P1 expression promote leukemic cell infiltration of lymph nodes in chronic lymphocytic leukemia L Patrussi, N Capitani, V Martini, M Pizzi, V Trimarco, F Frezzato, F Marino, ... Cancer research 75 (19), 4153-4163, 2015 | 52 | 2015 |
In chronic lymphocytic leukemia the JAK2/STAT3 pathway is constitutively activated and its inhibition leads to CLL cell death unaffected by the protective bone marrow … F Severin, F Frezzato, A Visentin, V Martini, V Trimarco, S Carraro, ... Cancers 11 (12), 1939, 2019 | 47 | 2019 |
Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia C Gattazzo, V Martini, F Frezzato, V Trimarco, E Tibaldi, M Castelli, ... haematologica 99 (6), 1069, 2014 | 46 | 2014 |
HS1, a Lyn kinase substrate, is abnormally expressed in B-chronic lymphocytic leukemia and correlates with response to fludarabine-based regimen F Frezzato, C Gattazzo, V Martini, V Trimarco, A Teramo, S Carraro, ... PLoS One 7 (6), e39902, 2012 | 44 | 2012 |
HSP70/HSF1 axis, regulated via a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia F Frezzato, F Raggi, V Martini, F Severin, V Trimarco, A Visentin, ... International journal of cancer 145 (11), 3089-3100, 2019 | 42 | 2019 |
Vascular perfusion kinetics by contrast-enhanced ultrasound are related to synovial microvascularity in the joints of psoriatic arthritis U Fiocco, R Stramare, A Coran, E Grisan, E Scagliori, F Caso, L Costa, ... Clinical rheumatology 34, 1903-1912, 2015 | 42 | 2015 |
Transcriptional network profile on synovial fluid T cells in psoriatic arthritis U Fiocco, V Martini, B Accordi, F Caso, L Costa, F Oliviero, A Scanu, ... Clinical rheumatology 34, 1571-1580, 2015 | 40 | 2015 |
T and B cell immune responses to influenza viruses in pigs B Holzer, V Martini, M Edmans, E Tchilian Frontiers in Immunology 10, 433399, 2019 | 39 | 2019 |
Cortactin, a Lyn substrate, is a checkpoint molecule at the intersection of BCR and CXCR4 signalling pathway in chronic lymphocytic leukaemia cells V Martini, C Gattazzo, F Frezzato, V Trimarco, M Pizzi, G Chiodin, ... British journal of haematology 178 (1), 81-93, 2017 | 37 | 2017 |
Integrated CLL scoring system, a new and simple index to predict time to treatment and overall survival in patients with chronic lymphocytic leukemia A Visentin, M Facco, F Frezzato, M Castelli, V Trimarco, V Martini, ... Clinical Lymphoma Myeloma and Leukemia 15 (10), 612-620. e5, 2015 | 37 | 2015 |
Lyn-mediated procaspase 8 dimerization blocks apoptotic signaling in B-cell chronic lymphocytic leukemia F Zonta, MA Pagano, L Trentin, E Tibaldi, F Frezzato, C Gattazzo, ... Blood, The Journal of the American Society of Hematology 123 (6), 875-883, 2014 | 34 | 2014 |
Prognostic and predictive effect of IGHV mutational status and load in chronic lymphocytic leukemia: focus on FCR and BR treatments A Visentin, M Facco, C Gurrieri, E Pagnin, V Martini, S Imbergamo, ... Clinical Lymphoma Myeloma and Leukemia 19 (10), 678-685. e4, 2019 | 33 | 2019 |
Insulin/IGF axis in breast cancer: clinical evidence and translational insights F Biello, F Platini, F D’avanzo, C Cattrini, A Mennitto, S Genestroni, ... Biomolecules 11 (1), 125, 2021 | 32 | 2021 |
Major infections, secondary cancers and autoimmune diseases occur in different clinical subsets of chronic lymphocytic leukaemia patients A Visentin, S Imbergamo, C Gurrieri, F Frezzato, V Trimarco, V Martini, ... European Journal of Cancer 72, 103-111, 2017 | 31 | 2017 |