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Brett T Staahl
Brett T Staahl
Roche Postdoctoral Fellow at University of California, Berkeley
Verified email at berkeley.edu
Title
Cited by
Cited by
Year
Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery
S Lin, BT Staahl, RK Alla, JA Doudna
elife 3, e04766, 2014
13432014
An essential switch in subunit composition of a chromatin remodeling complex during neural development
J Lessard, JI Wu, JA Ranish, M Wan, MM Winslow, BT Staahl, H Wu, ...
Neuron 55 (2), 201-215, 2007
8392007
MicroRNA-mediated switching of chromatin-remodelling complexes in neural development
AS Yoo, BT Staahl, L Chen, GR Crabtree
Nature 460 (7255), 642-646, 2009
7022009
An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency
L Ho, JL Ronan, J Wu, BT Staahl, L Chen, A Kuo, J Lessard, ...
Proceedings of the National Academy of Sciences 106 (13), 5181-5186, 2009
6562009
CasX enzymes comprise a distinct family of RNA-guided genome editors
JJ Liu, N Orlova, BL Oakes, E Ma, HB Spinner, KLM Baney, J Chuck, ...
Nature 566 (7743), 218-223, 2019
4102019
Rational design of a split-Cas9 enzyme complex
AV Wright, SH Sternberg, DW Taylor, BT Staahl, JA Bardales, JE Kornfeld, ...
Proceedings of the National Academy of Sciences 112 (10), 2984-2989, 2015
3652015
Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes
BT Staahl, M Benekareddy, C Coulon-Bainier, AA Banfal, SN Floor, ...
Nature biotechnology 35 (5), 431-434, 2017
3402017
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
BL Oakes, DC Nadler, A Flamholz, C Fellmann, BT Staahl, JA Doudna, ...
Nature biotechnology 34 (6), 646-651, 2016
2082016
Oxygen sensing in yeast: evidence for the involvement of the respiratory chain in regulating the transcription of a subset of hypoxic genes
KE Kwast, PV Burke, BT Staahl, RO Poyton
Proceedings of the National Academy of Sciences 96 (10), 5446-5451, 1999
2031999
A thermostable Cas9 with increased lifetime in human plasma
LB Harrington, D Paez-Espino, BT Staahl, JS Chen, E Ma, NC Kyrpides, ...
Nature communications 8 (1), 1424, 2017
1952017
Exome sequencing to identify de novo mutations in sporadic ALS trios
A Chesi, BT Staahl, A Jovičić, J Couthouis, M Fasolino, AR Raphael, ...
Nature neuroscience 16 (7), 851-855, 2013
1622013
Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways
BT Staahl, J Tang, W Wu, A Sun, AD Gitler, AS Yoo, GR Crabtree
Journal of Neuroscience 33 (25), 10348-10361, 2013
1322013
Yeast flavohemoglobin, a nitric oxide oxidoreductase, is located in both the cytosol and the mitochondrial matrix: effects of respiration, anoxia, and the mitochondrial genome …
N Cassanova, KM O'Brien, BT Stahl, T McClure, RO Poyton
Journal of Biological Chemistry 280 (9), 7645-7653, 2005
1032005
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
T Gaj, BT Staahl, GMC Rodrigues, P Limsirichai, FK Ekman, JA Doudna, ...
Nucleic acids research 45 (11), e98-e98, 2017
872017
Site-Specific Bioconjugation through Enzyme-Catalyzed Tyrosine–Cysteine Bond Formation
MJ Lobba, C Fellmann, AM Marmelstein, JC Maza, EN Kissman, ...
ACS Central Science 6 (9), 1564-1571, 2020
622020
Creating a neural specific chromatin landscape by npBAF and nBAF complexes
BT Staahl, GR Crabtree
Current opinion in neurobiology 23 (6), 903-913, 2013
502013
Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism
W Wenderski, L Wang, A Krokhotin, JJ Walsh, H Li, H Shoji, S Ghosh, ...
Proceedings of the National Academy of Sciences 117 (18), 10055-10066, 2020
382020
Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules
A Shams, SA Higgins, C Fellmann, TG Laughlin, BL Oakes, R Lew, S Kim, ...
Nature Communications 12 (1), 5664, 2021
372021
Methods and compositions for RNA-directed target DNA modification
JA Doudna, S Lin, BT Staahl
US Patent 10,570,418, 2020
162020
CRISPR-CasX is an RNA-dominated enzyme active for human genome editing
JJ Liu, N Orlova, BL Oakes, E Ma, HB Spinner, KLM Baney, J Chuck, ...
Nature 566 (7743), 218, 2019
92019
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