Experimental methods and modeling techniques for description of cell population heterogeneity RL Fernandes, M Nierychlo, L Lundin, AE Pedersen, PEP Tellez, A Dutta, ... Biotechnology advances 29 (6), 575-599, 2011 | 151 | 2011 |
Challenges in industrial fermentation technology research LR Formenti, A Nørregaard, A Bolic, DQ Hernandez, T Hagemann, ... Biotechnology journal 9 (6), 727-738, 2014 | 101 | 2014 |
Physiological heterogeneities in microbial populations and implications for physical stress tolerance M Carlquist, RL Fernandes, S Helmark, AL Heins, L Lundin, SJ Sørensen, ... Microbial cell factories 11, 1-13, 2012 | 89 | 2012 |
Population heterogeneity in microbial bioprocesses: origin, analysis, mechanisms, and future perspectives AL Heins, D Weuster-Botz Bioprocess and biosystems engineering 41, 889-916, 2018 | 77 | 2018 |
Experimental and in silico investigation of population heterogeneity in continuous Sachharomyces cerevisiae scale‐down fermentation in a two‐compartment setup AL Heins, R Lencastre Fernandes, KV Gernaey, AE Lantz Journal of Chemical Technology & Biotechnology 90 (2), 324-340, 2015 | 48 | 2015 |
Quantitative flow cytometry to understand population heterogeneity in response to changes in substrate availability in Escherichia coli and Saccharomyces cerevisiae chemostats AL Heins, T Johanson, S Han, L Lundin, M Carlquist, KV Gernaey, ... Frontiers in bioengineering and biotechnology 7, 187, 2019 | 39 | 2019 |
Applying mechanistic models in bioprocess development R Lencastre Fernandes, VK Bodla, M Carlquist, AL Heins, ... Measurement, monitoring, modelling and control of bioprocesses, 137-166, 2012 | 38 | 2012 |
Cell mass and cell cycle dynamics of an asynchronous budding yeast population: experimental observations, flow cytometry data analysis, and multi‐scale modeling RL Fernandes, M Carlquist, L Lundin, AL Heins, A Dutta, SJ Sørensen, ... Biotechnology and bioengineering 110 (3), 812-826, 2013 | 36 | 2013 |
Advances in automated real‐time flow cytometry for monitoring of bioreactor processes AL Heins, MD Hoang, D Weuster‐Botz Engineering in life sciences 22 (3-4), 260-278, 2022 | 20 | 2022 |
Development and characterization of Escherichia coli triple reporter strains for investigation of population heterogeneity in bioprocesses AL Heins, J Reyelt, M Schmidt, H Kranz, D Weuster-Botz Microbial cell factories 19, 1-20, 2020 | 16 | 2020 |
Untargeted GC‐MS Metabolomics Reveals Changes in the Metabolite Dynamics of Industrial Scale Batch Fermentations of Streptoccoccus thermophilus Broth B Khakimov, LD Christiansen, AL Heins, KM Sørensen, C Schöller, ... Biotechnology journal 12 (10), 1700400, 2017 | 14 | 2017 |
The effect of acetate on population heterogeneity in different cellular characteristics of Escherichia coli in aerobic batch cultures AL Heins, L Lundin, I Nunes, KV Gernaey, SJ Sørensen, AE Lantz Biotechnology Progress 35 (3), e2796, 2019 | 8 | 2019 |
Application of an Escherichia coli triple reporter strain for at‐line monitoring of single‐cell physiology during L‐phenylalanine production MD Hoang, DT Doan, M Schmidt, H Kranz, A Kremling, AL Heins Engineering in life sciences 23 (1), e2100162, 2023 | 6 | 2023 |
Applications of coarse-grained models in metabolic engineering DT Doan, MD Hoang, AL Heins, A Kremling Frontiers in Molecular Biosciences 9, 806213, 2022 | 5 | 2022 |
Impact of mixing insufficiencies on L-phenylalanine production with an Escherichia coli reporter strain in a novel two-compartment bioreactor MD Hoang, I Polte, L Frantzmann, N von den Eichen, AL Heins, ... Microbial cell factories 22 (1), 153, 2023 | 1 | 2023 |
Influence of Varying Pre-Culture Conditions on the Level of Population Heterogeneity in Batch Cultures with an Escherichia coli Triple Reporter Strain MD Hoang, S Riessner, JE Oropeza Vargas, N von den Eichen, AL Heins Microorganisms 11 (7), 1763, 2023 | 1 | 2023 |
Population heterogeneity in Saccharomyces cerevisiae and Escherichia coli lab scale cultivations simulating industrial scale bioprocesses AL Heins Technical University of Denmark, 2014 | 1 | 2014 |
Dynamics in population heterogeneity during batch and continuous fermentation of Saccharomyces cerevisiae AL Heins, RL Fernandes, L Lundin, M Carlquist, S Sörensen, K Gernaey, ... New Biotechnology 29, S199-S200, 2012 | 1 | 2012 |
Versteckte Vielfalt: Diversität von Zellen im industriellen Bioprozess P Arulrajah, AL Heins BIOspektrum 29 (3), 241-244, 2023 | | 2023 |
Hidden diversity: diversity of cells in industrial bioprocesses P Arulrajah, AL Heins BioSpektrum 29 (3), 241-244, 2023 | | 2023 |