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Anthony M. Pedley
Anthony M. Pedley
Verified email at psu.edu
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Cited by
Cited by
Year
A new view into the regulation of purine metabolism: the purinosome
AM Pedley, SJ Benkovic
Trends in biochemical sciences 42 (2), 141-154, 2017
2922017
Spatial colocalization and functional link of purinosomes with mitochondria
JB French, SA Jones, H Deng, AM Pedley, D Kim, CY Chan, H Hu, ...
Science 351 (6274), 733-737, 2016
1402016
Quantitative Analysis of Purine Nucleotides Indicates That Purinosomes Increase de Novo Purine Biosynthesis*♦
H Zhao, CR Chiaro, L Zhang, PB Smith, CY Chan, AM Pedley, RJ Pugh, ...
Journal of Biological Chemistry 290 (11), 6705-6713, 2015
902015
Purinosome formation as a function of the cell cycle
CY Chan, H Zhao, RJ Pugh, AM Pedley, J French, SA Jones, X Zhuang, ...
Proceedings of the National Academy of Sciences 112 (5), 1368-1373, 2015
792015
Microtubule-directed transport of purine metabolons drives their cytosolic transit to mitochondria
CY Chan, AM Pedley, D Kim, C Xia, X Zhuang, SJ Benkovic
Proceedings of the National Academy of Sciences 115 (51), 13009-13014, 2018
362018
Replication protein A dynamically regulates monoubiquitination of proliferating cell nuclear antigen
M Hedglin, M Aitha, A Pedley, SJ Benkovic
Journal of Biological Chemistry 294 (13), 5157-5168, 2019
202019
Flexibility of PCNA-protein interface accommodates differential binding partners
AM Pedley, MA Lill, VJ Davisson
PLoS One 9 (7), e102481, 2014
182014
Hypoxia drives the assembly of the multienzyme purinosome complex
C Doigneaux, AM Pedley, IN Mistry, M Papayova, SJ Benkovic, ...
Journal of Biological Chemistry 295 (28), 9551-9566, 2020
152020
Role of HSP90 in the Regulation of de Novo Purine Biosynthesis
AM Pedley, GI Karras, X Zhang, S Lindquist, SJ Benkovic
Biochemistry 57 (23), 3217-3221, 2018
142018
Conformational changes involving ammonia tunnel formation and allosteric control in GMP synthetase
JC Oliver, R Gudihal, JW Burgner, AM Pedley, AT Zwierko, VJ Davisson, ...
Archives of biochemistry and biophysics 545, 22-32, 2014
142014
Human de novo purine biosynthesis
V Pareek, AM Pedley, SJ Benkovic
Critical reviews in biochemistry and molecular biology 56 (1), 1-16, 2021
122021
Selective inhibition of STAT3 phosphorylation using a nuclear-targeted kinase inhibitor
MD Bartolowits, W Brown, R Ali, AM Pedley, Q Chen, KE Harvey, ...
ACS chemical biology 12 (9), 2371-2378, 2017
122017
Mapping post-translational modifications of de novo purine biosynthetic enzymes: implications for pathway regulation
C Liu, GM Knudsen, AM Pedley, J He, JL Johnson, TM Yaron, LC Cantley, ...
Journal of proteome research 18 (5), 2078-2087, 2019
82019
Detecting purinosome metabolon formation with fluorescence microscopy
AM Pedley, SJ Benkovic
Protein Complex Assembly, 279-289, 2018
62018
Identification of FAK substrate peptides via colorimetric screening of a one‐bead one‐peptide combinatorial library
LA Witucki, LS Borowicz, AM Pedley, J Curtis‐Fisk, EG Kuszpit
Journal of Peptide Science 21 (4), 302-311, 2015
32015
Purine biosynthetic enzymes assemble into liquid-like condensates dependent on the activity of chaperone protein HSP90
AM Pedley, JP Boylan, CY Chan, EL Kennedy, M Kyoung, SJ Benkovic
Journal of Biological Chemistry 298 (5), 2022
12022
The Purinosome: A Case Study for a Mammalian Metabolon
AM Pedley, V Pareek, SJ Benkovic
Annual Review of Biochemistry 91, 2022
2022
Dataset for: Hypoxia drives the assembly of the multi-enzyme purinosome complex
C Doigneaux, A Pedley, IN Mistry, M Papayova, S Benkovic, A Tavassoli
University of Southampton, 2020
2020
Observations on the Cellular Dynamics of a Metabolic Complex, the Purinosome
S Benkovic, CY Chan, D Kim, A Pedley, X Zhuang
The FASEB Journal 30, 240.1-240.1, 2016
2016
Molecular features that define specific PCNA-protein interactions in DNA repair
AM Pedley, LN Paul, VJ Davisson
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 245, 2013
2013
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Articles 1–20