Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus RK Perez, MG Gordon, M Subramaniam, MC Kim, GC Hartoularos, S Targ, ... Science 376 (6589), eabf1970, 2022 | 192 | 2022 |
dCas9-targeted locus-specific protein isolation method identifies histone gene regulators C Tsui, C Inouye, M Levy, A Lu, L Florens, MP Washburn, R Tjian Proceedings of the National Academy of Sciences 115 (12), E2734-E2741, 2018 | 64 | 2018 |
Targeting SRC coactivators blocks the tumor-initiating capacity of cancer stem-like cells AD Rohira, F Yan, L Wang, J Wang, S Zhou, A Lu, Y Yu, J Xu, DM Lonard, ... Cancer research 77 (16), 4293-4304, 2017 | 45 | 2017 |
Synthetic mammalian signaling circuits for robust cell population control Y Ma, MW Budde, MN Mayalu, J Zhu, AC Lu, RM Murray, MB Elowitz Cell 185 (6), 967-979. e12, 2022 | 37 | 2022 |
Multi-context genetic modeling of transcriptional regulation resolves novel disease loci M Thompson, MG Gordon, A Lu, A Tandon, E Halperin, A Gusev, CJ Ye, ... Nature communications 13 (1), 5704, 2022 | 11 | 2022 |
Fast and powerful statistical method for context-specific QTL mapping in multi-context genomic studies A Lu, M Thompson, M Grace Gordon, A Dahl, CJ Ye, N Zaitlen, B Balliu bioRxiv, 2021.06. 17.448889, 2021 | 8 | 2021 |
Mapping gene regulatory networks of primary CD4+ T cells using single-cell genomics and genome engineering RE Gate, MC Kim, A Lu, D Lee, E Shifrut, M Subramaniam, A Marson, ... bioRxiv, 678060, 2019 | 5 | 2019 |
Memento: generalized differential expression analysis of single-cell RNA-seq with method of moments estimation and efficient resampling MC Kim, R Gate, DS Lee, A Lu, E Gordon, E Shifrut, A Marson, V Ntranos, ... bioRxiv, 2022.11. 09.515836, 2022 | 3 | 2022 |
Stoichiometric expression of messenger polycistrons by eukaryotic ribosomes (SEMPER) for compact, ratio-tunable multi-gene expression from single mRNAs M Duan, I Dev, A Lu, MY You, MG Shapiro bioRxiv, 2023.05. 26.541240, 2023 | 2 | 2023 |
Protein-Based Signal Amplification AC Lu, MJ Flynn, LS Chong, R Zhu, MB Elowitz US Patent App. 18/486,875, 2024 | | 2024 |
Synthetic protein circuits for programmable control of mammalian cell death S Xia, AC Lu, V Tobin, K Luo, L Moeller, DJ Shon, R Du, JM Linton, M Sui, ... Cell, 2024 | | 2024 |