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Jun Jiang
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Protein expression and functional relevance of efflux and uptake drug transporters at the blood–brain barrier of human brain and glioblastoma
X Bao, J Wu, Y Xie, S Kim, S Michelhaugh, J Jiang, S Mittal, N Sanai, J Li
Clinical Pharmacology & Therapeutics 107 (5), 1116-1127, 2020
552020
Post-transcriptional modifications modulate rRNA structure and ligand interactions
J Jiang, H Seo, CS Chow
Accounts of chemical research 49 (5), 893-901, 2016
372016
Structure modulation of helix 69 from Escherichia coli 23S ribosomal RNA by pseudouridylations
J Jiang, R Aduri, CS Chow, J SantaLucia Jr
Nucleic acids research 42 (6), 3971-3981, 2014
302014
Physiologically based pharmacokinetic modeling of central nervous system pharmacokinetics of CDK4/6 inhibitors to guide selection of drug and dosing regimen for brain cancer …
J Li, J Jiang, J Wu, X Bao, N Sanai
Clinical Pharmacology & Therapeutics 109 (2), 494-506, 2021
222021
The RNA folding problems: different levels of sRNA structure prediction
F Sijenyi, P Saro, Z Ouyang, K Damm-Ganamet, M Wood, J Jiang, ...
RNA 3D structure analysis and prediction, 91-117, 2012
222012
Comparison of solution conformations and stabilities of modified helix 69 rRNA analogs from bacteria and human
M Sumita, J Jiang, J SantaLucia Jr, CS Chow
Biopolymers 97 (2), 94-106, 2012
222012
Quantitative protein expression of blood‐brain barrier transporters in the vasculature of brain metastases of patients with lung and breast cancer
X Bao, J Wu, J Jiang, AC Tien, N Sanai, J Li
Clinical and Translational Science 14 (4), 1265-1271, 2021
102021
Helix 69: a multitasking RNA motif as a novel drug target
J Jiang, Y Sakakibara, CS Chow
Israel Journal of Chemistry 53 (6‐7), 379-390, 2013
102013
Inhibition of cysteine protease papain by metal ions and polysulfide complexes, especially mercuric ion Mercury polysulfide complexes might be potential bioactive species in …
J Jiang, X Yang, K Wang
Journal of Chinese Pharmaceutical Sciences 16 (1), 1, 2007
102007
Mechanistic modeling of central nervous system pharmacokinetics and target engagement of HER2 Tyrosine Kinase inhibitors to inform treatment of breast cancer brain metastases
J Li, J Jiang, X Bao, V Kumar, SC Alley, S Peterson, AJ Lee
Clinical Cancer Research 28 (15), 3329-3341, 2022
92022
Modulation of conformational changes in helix 69 mutants by pseudouridine modifications
Jun Jiang, Daya Nidhi Kharel, Christine S. Chow
Biophysical Chemistry, 2015
82015
Amino acid-linked platinum (II) compounds: non-canonical nucleoside preferences and influence on glycosidic bond stabilities
B Kimutai, CC He, A Roberts, ML Jones, X Bao, J Jiang, Z Yang, ...
JBIC Journal of Biological Inorganic Chemistry 24, 985-997, 2019
62019
Evaluation and correction of injection order effects in LC-MS/MS based targeted metabolomics
Y Yue, X Bao, J Jiang, J Li
Journal of Chromatography B 1212, 123513, 2022
52022
DDRE-23. PRECLINICAL EVALUATION OF BRAIN PENETRATION PROPERTIES OF NEW FIRST-IN-CLASS LYSINE-SPECIFIC DEMETHYLASE 1 (LSD1) INHIBITOR, SP-2577
J Jiang, B Hopkins, G Hook, EL Melendez, A Tovmasyan, S Mehta, J Li, ...
Neuro-Oncology 23 (Suppl 6), vi79, 2021
22021
Development and validation of a liquid chromatography coupled with tandem mass spectrometry method for determining total and unbound pamiparib in human plasma and brain tumors
J Jiang, X Bao, Y Yue, D Schiff, R Bindra, J Li
Biomedical Chromatography 36 (12), e5478, 2022
12022
287MO A phase 0 ‘trigger’trial of pamiparib in newly diagnosed and recurrent glioblastoma patients
N Sanai, SN Mehta, YW Chang, J Jiang, J Molloy, C Pennington-Krygier, ...
Annals of Oncology 33, S670, 2022
12022
Abstract CT125: A phase 0/2 ‘trigger’trial of pamiparib or olaparib plus radiotherapy in patients with newly-diagnosed or recurrent glioblastoma
N Sanai, YW Chang, J Jiang, J Molloy, C Pennington-Krygier, J Harmon, ...
Cancer Research 84 (7_Supplement), CT125-CT125, 2024
2024
Differential metabolic response of triple-negative and estrogen receptor-positive breast cancer cells to abemaciclib, a CDK4/6 inhibitor
J Jiang, X Bao, Y Jiang, Y Yue, M Huettemann, J Li
Cancer Research 84 (6_Supplement), 4424-4424, 2024
2024
SINGLE CELL TRANSCRIPTOMICS, PHARMACOKINETICS, AND PHARMACODYNAMICS OF COMBINED CDK4/6 AND MTOR INHIBITION IN A PHASE 0 TRIAL OF RECURRENT HIGH-GRADE GLIOMA
K Johnson, AC Tien, J Jiang, J McNamara, YW Chang, C Montgomery, ...
NEURO-ONCOLOGY 25, 2023
2023
A Combined Phase 0/2" Trigger" Trial Evaluating Pamiparib or Olaparib with Concurrent Radiotherapy in Patients with Newly-Diagnosed or Recurrent Glioblastoma
WR Kennedy, YW Chang, J Jiang, J Molloy, C Pennington-Krygier, ...
International Journal of Radiation Oncology, Biology, Physics 117 (2), e115, 2023
2023
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