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Ganesan Senthil Kumar
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Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code
MS Choy, M Hieke, GS Kumar, GR Lewis, KR Gonzalez-DeWhitt, ...
Proceedings of the National Academy of Sciences 111 (11), 4097-4102, 2014
1402014
Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2
Q Luo, K Viste, JC Urday-Zaa, G Senthil Kumar, WW Tsai, A Talai, ...
Proceedings of the National Academy of Sciences 109 (51), 20865-20870, 2012
1062012
The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism
GS Kumar, E Gokhan, S De Munter, M Bollen, P Vagnarelli, W Peti, ...
Elife 5, e16539, 2016
672016
Dynamic activation and regulation of the mitogen-activated protein kinase p38
GS Kumar, MW Clarkson, MBA Kunze, D Granata, AJ Wand, ...
Proceedings of the National Academy of Sciences 115 (18), 4655-4660, 2018
622018
ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail
MT Bertran, S Mouilleron, Y Zhou, R Bajaj, F Uliana, GS Kumar, ...
Nature communications 10 (1), 771, 2019
512019
High level expression of peptides and proteins using cytochrome b5 as a fusion host
A Mitra, KS Chakrabarti, MSS Hameed, KV Srinivas, GS Kumar, ...
Protein expression and purification 41 (1), 84-97, 2005
442005
Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38
K Kirsch, A Zeke, O Tőke, P Sok, A Sethi, A Sebő, GS Kumar, P Egri, ...
Nature Communications 11 (1), 5769, 2020
392020
Solution structure of the mSin3A PAH2–Pf1 SID1 complex: a Mad1/Mxd1-like interaction disrupted by MRG15 in the Rpd3S/Sin3S complex
GS Kumar, T Xie, Y Zhang, I Radhakrishnan
Journal of molecular biology 408 (5), 987-1000, 2011
372011
Sequence requirements for combinatorial recognition of histone H3 by the MRG15 and Pf1 subunits of the Rpd3S/Sin3S corepressor complex
GS Kumar, W Chang, T Xie, A Patel, Y Zhang, GG Wang, G David, ...
Journal of molecular biology 422 (4), 519-531, 2012
332012
Structural basis for molecular interactions involving MRG domains: implications in chromatin biology
T Xie, R Graveline, GS Kumar, Y Zhang, A Krishnan, G David, ...
Structure 20 (1), 151-160, 2012
322012
Identification of the substrate recruitment mechanism of the muscle glycogen protein phosphatase 1 holoenzyme
GS Kumar, MS Choy, DM Koveal, MK Lorinsky, SP Lyons, AN Kettenbach, ...
Science Advances 4 (11), eaau6044, 2018
272018
Cooperative dynamics across distinct structural elements regulate PTP1B activity
KR Torgeson, MW Clarkson, GS Kumar, R Page, W Peti
Journal of Biological Chemistry 295 (40), 13829-13837, 2020
242020
The differential regulation of p38α by the neuronal kinase interaction motif protein tyrosine phosphatases, a detailed molecular study
DM Francis, GS Kumar, D Koveal, A Tortajada, R Page, W Peti
Structure 21 (9), 1612-1623, 2013
242013
Overexpression, purification, and pharmacological activity of a biosynthetically derived conopeptide
GS Kumar, P Ramasamy, SK Sikdar, SP Sarma
Biochemical and biophysical research communications 335 (3), 965-972, 2005
242005
The mode of action of the Protein tyrosine phosphatase 1B inhibitor Ertiprotafib
GS Kumar, R Page, W Peti
Plos one 15 (10), e0240044, 2020
202020
Optimization, produc‑tion and partial purification of extracellular α‑amylase from Bacillus sp
A Krishnan, G Kumar, K Loganathan, B Rao
Marini. Arch. Appl. Sci. Res 3 (1), 33-42, 2011
202011
Structural Basis for the Regulation of the Mitogen-activated Protein (MAP) Kinase p38α by the Dual Specificity Phosphatase 16 MAP Kinase Binding Domain in Solution*♦
GS Kumar, H Zettl, R Page, W Peti
Journal of Biological Chemistry 288 (39), 28347-28356, 2013
16*2013
Molecular basis for the mechanism of constitutive CBP/p300 coactivator recruitment by CRTC1-MAML2 and its implications in cAMP signaling
MD Clark, GS Kumar, R Marcum, Q Luo, Y Zhang, I Radhakrishnan
Biochemistry 54 (35), 5439-5446, 2015
152015
Solution Structure of δ‐Am2766: A Highly Hydrophobic δ‐Conotoxin from Conus amadis That Inhibits Inactivation of Neuronal Voltage‐Gated Sodium Channels
SP Sarma, GS Kumar, S Sudarslal, P Iengar, P Ramasamy, SK Sikdar, ...
Chemistry & biodiversity 2 (4), 535-556, 2005
152005
MAP kinase-mediated activation of RSK1 and MK2 substrate kinases
P Sok, G Gógl, GS Kumar, A Alexa, N Singh, K Kirsch, A Sebő, L Drahos, ...
Structure 28 (10), 1101-1113. e5, 2020
122020
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