Understanding the antagonism of retinoblastoma protein dephosphorylation by PNUTS provides insights into the PP1 regulatory code MS Choy, M Hieke, GS Kumar, GR Lewis, KR Gonzalez-DeWhitt, ... Proceedings of the National Academy of Sciences 111 (11), 4097-4102, 2014 | 140 | 2014 |
Mechanism of CREB recognition and coactivation by the CREB-regulated transcriptional coactivator CRTC2 Q Luo, K Viste, JC Urday-Zaa, G Senthil Kumar, WW Tsai, A Talai, ... Proceedings of the National Academy of Sciences 109 (51), 20865-20870, 2012 | 106 | 2012 |
The Ki-67 and RepoMan mitotic phosphatases assemble via an identical, yet novel mechanism GS Kumar, E Gokhan, S De Munter, M Bollen, P Vagnarelli, W Peti, ... Elife 5, e16539, 2016 | 67 | 2016 |
Dynamic activation and regulation of the mitogen-activated protein kinase p38 GS Kumar, MW Clarkson, MBA Kunze, D Granata, AJ Wand, ... Proceedings of the National Academy of Sciences 115 (18), 4655-4660, 2018 | 62 | 2018 |
ASPP proteins discriminate between PP1 catalytic subunits through their SH3 domain and the PP1 C-tail MT Bertran, S Mouilleron, Y Zhou, R Bajaj, F Uliana, GS Kumar, ... Nature communications 10 (1), 771, 2019 | 51 | 2019 |
High level expression of peptides and proteins using cytochrome b5 as a fusion host A Mitra, KS Chakrabarti, MSS Hameed, KV Srinivas, GS Kumar, ... Protein expression and purification 41 (1), 84-97, 2005 | 44 | 2005 |
Co-regulation of the transcription controlling ATF2 phosphoswitch by JNK and p38 K Kirsch, A Zeke, O Tőke, P Sok, A Sethi, A Sebő, GS Kumar, P Egri, ... Nature Communications 11 (1), 5769, 2020 | 39 | 2020 |
Solution structure of the mSin3A PAH2–Pf1 SID1 complex: a Mad1/Mxd1-like interaction disrupted by MRG15 in the Rpd3S/Sin3S complex GS Kumar, T Xie, Y Zhang, I Radhakrishnan Journal of molecular biology 408 (5), 987-1000, 2011 | 37 | 2011 |
Sequence requirements for combinatorial recognition of histone H3 by the MRG15 and Pf1 subunits of the Rpd3S/Sin3S corepressor complex GS Kumar, W Chang, T Xie, A Patel, Y Zhang, GG Wang, G David, ... Journal of molecular biology 422 (4), 519-531, 2012 | 33 | 2012 |
Structural basis for molecular interactions involving MRG domains: implications in chromatin biology T Xie, R Graveline, GS Kumar, Y Zhang, A Krishnan, G David, ... Structure 20 (1), 151-160, 2012 | 32 | 2012 |
Identification of the substrate recruitment mechanism of the muscle glycogen protein phosphatase 1 holoenzyme GS Kumar, MS Choy, DM Koveal, MK Lorinsky, SP Lyons, AN Kettenbach, ... Science Advances 4 (11), eaau6044, 2018 | 27 | 2018 |
Cooperative dynamics across distinct structural elements regulate PTP1B activity KR Torgeson, MW Clarkson, GS Kumar, R Page, W Peti Journal of Biological Chemistry 295 (40), 13829-13837, 2020 | 24 | 2020 |
The differential regulation of p38α by the neuronal kinase interaction motif protein tyrosine phosphatases, a detailed molecular study DM Francis, GS Kumar, D Koveal, A Tortajada, R Page, W Peti Structure 21 (9), 1612-1623, 2013 | 24 | 2013 |
Overexpression, purification, and pharmacological activity of a biosynthetically derived conopeptide GS Kumar, P Ramasamy, SK Sikdar, SP Sarma Biochemical and biophysical research communications 335 (3), 965-972, 2005 | 24 | 2005 |
The mode of action of the Protein tyrosine phosphatase 1B inhibitor Ertiprotafib GS Kumar, R Page, W Peti Plos one 15 (10), e0240044, 2020 | 20 | 2020 |
Optimization, produc‑tion and partial purification of extracellular α‑amylase from Bacillus sp A Krishnan, G Kumar, K Loganathan, B Rao Marini. Arch. Appl. Sci. Res 3 (1), 33-42, 2011 | 20 | 2011 |
Structural Basis for the Regulation of the Mitogen-activated Protein (MAP) Kinase p38α by the Dual Specificity Phosphatase 16 MAP Kinase Binding Domain in Solution*♦ GS Kumar, H Zettl, R Page, W Peti Journal of Biological Chemistry 288 (39), 28347-28356, 2013 | 16* | 2013 |
Molecular basis for the mechanism of constitutive CBP/p300 coactivator recruitment by CRTC1-MAML2 and its implications in cAMP signaling MD Clark, GS Kumar, R Marcum, Q Luo, Y Zhang, I Radhakrishnan Biochemistry 54 (35), 5439-5446, 2015 | 15 | 2015 |
Solution Structure of δ‐Am2766: A Highly Hydrophobic δ‐Conotoxin from Conus amadis That Inhibits Inactivation of Neuronal Voltage‐Gated Sodium Channels SP Sarma, GS Kumar, S Sudarslal, P Iengar, P Ramasamy, SK Sikdar, ... Chemistry & biodiversity 2 (4), 535-556, 2005 | 15 | 2005 |
MAP kinase-mediated activation of RSK1 and MK2 substrate kinases P Sok, G Gógl, GS Kumar, A Alexa, N Singh, K Kirsch, A Sebő, L Drahos, ... Structure 28 (10), 1101-1113. e5, 2020 | 12 | 2020 |