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Benjamin J Tombling
Benjamin J Tombling
Verified email at uq.edu.au
Title
Cited by
Cited by
Year
Ribosomally-synthesised cyclic peptides from plants as drug leads and pharmaceutical scaffolds
DJ Craik, MH Lee, FBH Rehm, B Tombling, B Doffek, H Peacock
Bioorganic & medicinal chemistry 26 (10), 2727-2737, 2018
442018
EGF‐like and other disulfide‐rich microdomains as therapeutic scaffolds
BJ Tombling, CK Wang, DJ Craik
Angewandte Chemie International Edition 59 (28), 11218-11232, 2020
382020
The emerging landscape of peptide-based inhibitors of PCSK9
BJ Tombling, Y Zhang, YH Huang, DJ Craik, CK Wang
Atherosclerosis 330, 52-60, 2021
262021
Bioactive cyclization optimizes the affinity of a proprotein convertase subtilisin/kexin type 9 (PCSK9) peptide inhibitor
BJ Tombling, C Lammi, N Lawrence, EK Gilding, G Grazioso, DJ Craik, ...
Journal of Medicinal Chemistry 64 (5), 2523-2533, 2020
152020
In Planta Discovery and Chemical Synthesis of Bracelet Cystine Knot Peptides from Rinorea bengalensis
TT Dang, LY Chan, BJ Tombling, PJ Harvey, EK Gilding, DJ Craik
Journal of Natural Products 84 (2), 395-407, 2021
112021
Engineered EGF-A peptides with improved affinity for proprotein convertase subtilisin/kexin type 9 (PCSK9)
BJ Tombling, C Lammi, N Lawrence, J Li, A Arnoldi, DJ Craik, CK Wang
ACS Chemical Biology 16 (2), 429-439, 2021
72021
Increased valency improves inhibitory activity of peptides targeting proprotein convertase subtilisin/kexin type 9 (PCSK9)
BJ Tombling, C Lammi, C Bollati, A Anoldi, DJ Craik, CK Wang
ChemBioChem 22 (12), 2154-2160, 2021
52021
The acyclotide ribe 31 from Rinorea bengalensis has selective cytotoxicity and potent insecticidal properties in Drosophila
TT Dang, YH Huang, S Ott, PJ Harvey, EK Gilding, BJ Tombling, LY Chan, ...
Journal of Biological Chemistry 298 (10), 2022
32022
Improving Stability Enhances In Vivo Efficacy of a PCSK9 Inhibitory Peptide
Y Zhang, L Wang, BJ Tombling, C Lammi, YH Huang, Y Li, M Bartolomei, ...
Journal of the American Chemical Society 144 (42), 19485-19498, 2022
12022
EGF‐artige und andere disulfidreiche Mikrodomänen als therapeutische Molekülgerüste
BJ Tombling, CK Wang, DJ Craik
Angewandte Chemie 132 (28), 11314-11328, 2020
12020
Cystine-knot peptide inhibitors of HTRA1 bind to a cryptic pocket within the active site region
Y Li, Y Wei, M Ultsch, W Li, W Tang, B Tombling, X Gao, Y Dimitrova, ...
Nature Communications 15 (1), 4359, 2024
2024
The development of peptide-based cholesterol-lowering therapeutics
B Tombling
2021
m-Terphenyl-stabilized boron (bis) triflates
D Vidovic, DCH Do, BJ Tombling, SP Koo
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015
2015
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Articles 1–13