UV irradiation induces a non-coding RNA that functionally opposes the protein encoded by the same gene L Williamson, M Saponaro, S Boeing, P East, R Mitter, T Kantidakis, ... Cell 168 (5), 843-855. e13, 2017 | 192 | 2017 |
Multiomic analysis of the UV-induced DNA damage response S Boeing, L Williamson, V Encheva, I Gori, RE Saunders, R Instrell, ... Cell reports 15 (7), 1597-1610, 2016 | 182 | 2016 |
NRG1 Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in KRAS Wild-Type Pancreatic Ductal Adenocarcinoma MR Jones, LM Williamson, JT Topham, MKC Lee, A Goytain, J Ho, ... Clinical Cancer Research 25 (15), 4674-4681, 2019 | 145 | 2019 |
Altered gene expression along the glycolysis–cholesterol synthesis axis is associated with outcome in pancreatic cancer JM Karasinska, JT Topham, SE Kalloger, GH Jang, RE Denroche, ... Clinical Cancer Research 26 (1), 135-146, 2020 | 136 | 2020 |
Pan-cancer analysis of advanced patient tumors reveals interactions between therapy and genomic landscapes E Pleasance, E Titmuss, L Williamson, H Kwan, L Culibrk, EY Zhao, ... Nature Cancer 1 (4), 452-468, 2020 | 124 | 2020 |
Estrogen receptor α-mediated transcription induces cell cycle-dependent DNA double-strand breaks LM Williamson, SP Lees-Miller Carcinogenesis 32 (3), 279-285, 2011 | 116 | 2011 |
Genomic features and classification of homologous recombination deficient pancreatic ductal adenocarcinoma T Golan, GM O’Kane, RE Denroche, M Raitses-Gurevich, RC Grant, ... Gastroenterology 160 (6), 2119-2132. e9, 2021 | 99 | 2021 |
Genome and transcriptome biomarkers of response to immune checkpoint inhibitors in advanced solid tumors A Pender, E Titmuss, ED Pleasance, KY Fan, H Pearson, SD Brown, ... Clinical Cancer Research 27 (1), 202-212, 2021 | 64 | 2021 |
Whole-genome and transcriptome analysis enhances precision cancer treatment options E Pleasance, A Bohm, LM Williamson, JMT Nelson, Y Shen, M Bonakdar, ... Annals of Oncology 33 (9), 939-949, 2022 | 59 | 2022 |
Chemical genetics of zipper-interacting protein kinase reveal myosin light chain as a bona fide substrate in permeabilized arterial smooth muscle LD Moffat, SBA Brown, ME Grassie, A Ulke-Lemée, LM Williamson, ... Journal of Biological Chemistry 286 (42), 36978-36991, 2011 | 47 | 2011 |
Subtype-discordant pancreatic ductal adenocarcinoma tumors show intermediate clinical and molecular characteristics JT Topham, JM Karasinska, MKC Lee, V Csizmok, LM Williamson, ... Clinical Cancer Research 27 (1), 150-157, 2021 | 32 | 2021 |
Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury LM Williamson, CM Rive, D Di Francesco, E Titmuss, HJE Chun, ... NPJ Precision Oncology 5 (1), 103, 2021 | 24 | 2021 |
Delving into early-onset pancreatic ductal adenocarcinoma: how does age fit in? ES Tsang, JT Topham, JM Karasinska, MKC Lee, LM Williamson, ... Clinical Cancer Research 27 (1), 246-254, 2021 | 22 | 2021 |
Genomic characterization of a well-differentiated grade 3 pancreatic neuroendocrine tumor LM Williamson, M Steel, JK Grewal, ML Thibodeau, EY Zhao, JM Loree, ... Molecular Case Studies 5 (3), a003814, 2019 | 22 | 2019 |
Uncovering clinically relevant gene fusions with integrated genomic and transcriptomic profiling of metastatic cancers ES Tsang, CJ Grisdale, E Pleasance, JT Topham, K Mungall, C Reisle, ... Clinical Cancer Research 27 (2), 522-531, 2021 | 16 | 2021 |
Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma JT Topham, ES Tsang, JM Karasinska, A Metcalfe, H Ali, SE Kalloger, ... Nature Communications 13 (1), 5941, 2022 | 15 | 2022 |
Endogenous retrovirus transcript levels are associated with immunogenic signatures in multiple metastatic cancer types JT Topham, E Titmuss, ED Pleasance, LM Williamson, JM Karasinska, ... Molecular cancer therapeutics 19 (9), 1889-1897, 2020 | 12 | 2020 |
A platform for oncogenomic reporting and interpretation C Reisle, LM Williamson, E Pleasance, A Davies, B Pellegrini, DW Bleile, ... Nature Communications 13 (1), 756, 2022 | 11 | 2022 |
Rearrangement-mediated cis-regulatory alterations in advanced patient tumors reveal interactions with therapy Y Zhang, F Chen, E Pleasance, L Williamson, CJ Grisdale, E Titmuss, ... Cell reports 37 (7), 2021 | 9 | 2021 |
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration ES Tsang, V Csizmok, LM Williamson, E Pleasance, JT Topham, ... NPJ Precision Oncology 7 (1), 31, 2023 | 6 | 2023 |