Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis CLG Lin, LA Bristol, L Jin, M Dykes-Hoberg, T Crawford, L Clawson, ... Neuron 20 (3), 589-602, 1998 | 826 | 1998 |
Cloning and expression of a cocaine-sensitive dopamine transporter complementary DNA S Shimada, S Kitayama, CL Lin, A Patel, E Nanthakumar, P Gregor, ... Science 254 (5031), 576-578, 1991 | 729 | 1991 |
Oxidative damage to RNA: mechanisms, consequences, and diseases Q Kong, CG Lin Cellular and Molecular Life Sciences 67, 1817-1829, 2010 | 413 | 2010 |
Increased expression of the glial glutamate transporter EAAT2 modulates excitotoxicity and delays the onset but not the outcome of ALS in mice H Guo, L Lai, MER Butchbach, MP Stockinger, X Shan, GA Bishop, ... Human molecular genetics 12 (19), 2519-2532, 2003 | 342 | 2003 |
Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins M Jackson, W Song, MY Liu, L Jin, M Dykes-Hoberg, CG Lin, WJ Bowers, ... Nature 410 (6824), 89-93, 2001 | 309 | 2001 |
Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18 CG Lin, I Orlov, AM Ruggiero, M Dykes-Hoberg, A Lee, M Jackson, ... Nature 410 (6824), 84-88, 2001 | 279 | 2001 |
Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS Y Chang, Q Kong, X Shan, G Tian, H Ilieva, DW Cleveland, JD Rothstein, ... PloS one 3 (8), e2849, 2008 | 267 | 2008 |
Messenger RNA oxidation is an early event preceding cell death and causes reduced protein expression X Shan, Y Chang, C Glenn Lin The FASEB Journal 21 (11), 2753-2764, 2007 | 224 | 2007 |
The identification and characterization of oxidized RNAs in Alzheimer's disease X Shan, H Tashiro, CG Lin Journal of Neuroscience 23 (12), 4913-4921, 2003 | 220 | 2003 |
Association of excitatory amino acid transporters, especially EAAT2, with cholesterol-rich lipid raft microdomains: importance for excitatory amino acid transporter … MER Butchbach, G Tian, H Guo, CG Lin Journal of Biological Chemistry 279 (33), 34388-34396, 2004 | 194 | 2004 |
Glutamate transporter EAAT2: regulation, function, and potential as a therapeutic target for neurological and psychiatric disease K Takahashi, JB Foster, CLG Lin Cellular and Molecular Life Sciences 72, 3489-3506, 2015 | 168 | 2015 |
Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection Q Kong, LC Chang, K Takahashi, Q Liu, DA Schulte, L Lai, B Ibabao, ... The Journal of clinical investigation 124 (3), 1255-1267, 2014 | 155 | 2014 |
Quantification of oxidized RNAs in Alzheimer's disease X Shan, CG Lin Neurobiology of Aging 27 (5), 657-662, 2006 | 146 | 2006 |
Glutamate transporter EAAT2: a new target for the treatment of neurodegenerative diseases CLG Lin, Q Kong, GD Cuny, MA Glicksman Future medicinal chemistry 4 (13), 1689-1700, 2012 | 143 | 2012 |
Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis M Aoki, CLG Lin, JD Rothstein, BA Geller, BA Hosler, TL Munsat, ... Annals of Neurology: Official Journal of the American Neurological …, 1998 | 141 | 1998 |
Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease K Takahashi, Q Kong, Y Lin, N Stouffer, DA Schulte, L Lai, Q Liu, ... Journal of experimental medicine 212 (3), 319-332, 2015 | 134 | 2015 |
Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity CK Colton, Q Kong, L Lai, MX Zhu, KI Seyb, GD Cuny, J Xian, ... Journal of biomolecular screening 15 (6), 653-662, 2010 | 103 | 2010 |
Increased expression of cholesterol 24S‐hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer’s disease G Tian, Q Kong, L Lai, A Ray‐Chaudhury, CG Lin Journal of neurochemistry 113 (4), 978-989, 2010 | 103 | 2010 |
Translational control of glial glutamate transporter EAAT2 expression G Tian, L Lai, H Guo, Y Lin, MER Butchbach, Y Chang, CG Lin Journal of biological chemistry 282 (3), 1727-1737, 2007 | 94 | 2007 |
Increased glial glutamate transporter EAAT2 expression reduces epileptogenic processes following pilocarpine-induced status epilepticus Q Kong, K Takahashi, D Schulte, N Stouffer, Y Lin, CLG Lin Neurobiology of disease 47 (2), 145-154, 2012 | 92 | 2012 |