Age-dependent neurodegeneration and Alzheimer-amyloid plaque formation in transgenic Drosophila I Greeve, D Kretzschmar, JA Tschäpe, A Beyn, C Brellinger, M Schweizer, ... Journal of Neuroscience 24 (16), 3899-3906, 2004 | 355 | 2004 |
The swiss cheese mutant causes glial hyperwrapping and brain degeneration in Drosophila D Kretzschmar, G Hasan, S Sharma, M Heisenberg, S Benzer Journal of Neuroscience 17 (19), 7425-7432, 1997 | 329 | 1997 |
The genetic basis of cerebral palsy MC Fahey, AH Maclennan, D Kretzschmar, J Gecz, MC Kruer Developmental Medicine & Child Neurology 59 (5), 462-469, 2017 | 205 | 2017 |
The circadian clock gene period extends healthspan in aging Drosophila melanogaster N Krishnan, D Kretzschmar, K Rakshit, E Chow, JM Giebultowicz Aging (Albany NY) 1 (11), 937, 2009 | 172 | 2009 |
Loss of Swiss cheese/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila M Mühlig-Versen, AB Da Cruz, JA Tschäpe, M Moser, R Büttner, ... Journal of Neuroscience 25 (11), 2865-2873, 2005 | 167 | 2005 |
The neurodegeneration mutant löchrig interferes with cholesterol homeostasis and Appl processing JA Tschäpe, C Hammerschmied, M Mühlig‐Versen, K Athenstaedt, ... The EMBO journal, 2002 | 157 | 2002 |
Neurotoxic effects induced by the Drosophila amyloid-β peptide suggest a conserved toxic function K Carmine-Simmen, T Proctor, J Tschäpe, B Poeck, T Triphan, R Strauss, ... Neurobiology of disease 33 (2), 274-281, 2009 | 140 | 2009 |
Placental failure and impaired vasculogenesis result in embryonic lethality for neuropathy target esterase-deficient mice M Moser, Y Li, K Vaupel, D Kretzschmar, R Kluge, P Glynn, R Buettner Molecular and Cellular Biology 24 (4), 1667-1679, 2004 | 139 | 2004 |
The Drosophila carbonyl reductase sniffer prevents oxidative stress-induced neurodegeneration JA Botella, JK Ulschmid, C Gruenewald, C Moehle, D Kretzschmar, ... Current Biology 14 (9), 782-786, 2004 | 113 | 2004 |
Loss of circadian clock accelerates aging in neurodegeneration-prone mutants N Krishnan, K Rakshit, ES Chow, JS Wentzell, D Kretzschmar, ... Neurobiology of disease 45 (3), 1129-1135, 2012 | 111 | 2012 |
Loss-of-Function Mutations in PNPLA6 Encoding Neuropathy Target Esterase Underlie Pubertal Failure and Neurological Deficits in Gordon Holmes Syndrome AK Topaloglu, A Lomniczi, D Kretzschmar, GA Dissen, LD Kotan, ... The Journal of Clinical Endocrinology & Metabolism 99 (10), E2067-E2075, 2014 | 109 | 2014 |
Disruption of the MAP1B-related protein FUTSCH leads to changes in the neuronal cytoskeleton, axonal transport defects, and progressive neurodegeneration in Drosophila AB Da Cruz, M Schwärzel, S Schulze, M Niyyati, M Heisenberg, ... Molecular biology of the cell 16 (5), 2433-2442, 2005 | 97 | 2005 |
Mutations in PNPLA6 are linked to photoreceptor degeneration and various forms of childhood blindness S Kmoch, J Majewski, V Ramamurthy, S Cao, S Fahiminiya, H Ren, ... Nature communications 6 (1), 5614, 2015 | 92 | 2015 |
Cloning and expression of the murine sws/NTE gene M Moser, T Stempfl, Y Li, P Glynn, R Büttner, D Kretzschmar Mechanisms of development 90 (2), 279-282, 2000 | 77 | 2000 |
Defective Pigment Granule Biogenesis and Aberrant Behavior Caused by Mutations in the Drosophila AP-3β Adaptin Gene ruby D Kretzschmar, B Poeck, H Roth, R Ernst, A Keller, M Porsch, R Strauss, ... Genetics 155 (1), 213-223, 2000 | 76 | 2000 |
Daily blue-light exposure shortens lifespan and causes brain neurodegeneration in Drosophila TR Nash, ES Chow, AD Law, SD Fu, E Fuszara, A Bilska, P Bebas, ... NPJ aging and mechanisms of disease 5 (1), 8, 2019 | 70 | 2019 |
Mutations in gamma adducin are associated with inherited cerebral palsy MC Kruer, T Jepperson, S Dutta, RD Steiner, E Cottenie, L Sanford, ... Annals of neurology 74 (6), 805-814, 2013 | 67 | 2013 |
Glial and neuronal expression of polyglutamine proteins induce behavioral changes and aggregate formation in Drosophila D Kretzschmar, J Tschäpe, A Bettencourt Da Cruz, E Asan, B Poeck, ... Glia 49 (1), 59-72, 2005 | 67 | 2005 |
Giant lens, a gene involved in cell determination and axon guidance in the visual system of Drosophila melanogaster. D Kretzschmar, A Brunner, V Wiersdorff, GO Pflugfelder, M Heisenberg, ... The EMBO Journal 11 (7), 2531-2539, 1992 | 65 | 1992 |
Swiss Cheese, a protein involved in progressive neurodegeneration, acts as a noncanonical regulatory subunit for PKA-C3 AB Da Cruz, J Wentzell, D Kretzschmar Journal of Neuroscience 28 (43), 10885-10892, 2008 | 61 | 2008 |