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Lam Tan Khuat
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Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade
Z Wang, EG Aguilar, JI Luna, C Dunai, LT Khuat, CT Le, A Mirsoian, ...
Nature medicine 25 (1), 141-151, 2019
7112019
Minimal PD-1 expression in mouse and human NK cells under diverse conditions
SJ Judge, C Dunai, EG Aguilar, SC Vick, IR Sturgill, LT Khuat, KM Stoffel, ...
The Journal of Clinical Investigation 130 (6), 3051-3068, 2020
1312020
Transplantation of nonexpanded adipose stromal vascular fraction and platelet‐rich plasma for articular cartilage injury treatment in mice model
P Van Pham, K Hong-Thien Bui, D Quoc Ngo, L Tan Khuat, N Kim Phan
Journal of Medical Engineering 2013 (1), 832396, 2013
442013
Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation
LT Khuat, CT Le, CCS Pai, RR Shields-Cutler, SG Holtan, A Rashidi, ...
Science Translational Medicine 12 (571), 2020
372020
Licensing delineates helper and effector NK cell subsets during viral infection
AE Zamora, EG Aguilar, CM Sungur, LT Khuat, C Dunai, GR Lochhead, ...
JCI insight 2 (10), 2017
342017
A simple in vitro method for evaluating dendritic cell-based vaccinations
PV Pham, NT Nguyen, HM Nguyen, LT Khuat, PM Le, VQ Pham, ...
OncoTargets and therapy, 1455-1464, 2014
162014
PD-1 Blockade reverses obesity-mediated T cell priming impairment
CT Le, LT Khuat, SE Caryotakis, M Wang, C Dunai, AV Nguyen, LV Vick, ...
Frontiers in immunology 11, 590568, 2020
152020
IL-2 and Anti-TGF-β Promote NK Cell Reconstitution and Anti-tumor Effects after Syngeneic Hematopoietic Stem Cell Transplantation
M Alvarez, C Dunai, LT Khuat, EG Aguilar, I Barao, WJ Murphy
Cancers 12 (11), 3189, 2020
132020
Mechanisms by Which Obesity Promotes Acute Graft-Versus-Host Disease in Mice
LT Khuat, LV Vick, E Choi, C Dunai, AA Merleev, E Maverakis, BR Blazar, ...
Frontiers in immunology 12, 752484, 2021
112021
Therapeutic effects of a NEDD8-activating enzyme inhibitor, pevonedistat, on sclerodermatous graft-versus-host disease in mice
CCS Pai, LT Khuat, M Chen, WJ Murphy, M Abedi
Biology of Blood and Marrow Transplantation 23 (1), 30-37, 2017
112017
Aging augments obesity-induced thymic involution and peripheral T cell exhaustion altering the" obesity paradox"
LVV Vick, CPP Collins, LTT Khuat, Z Wang, C Dunai, EGG Aguilar, ...
Frontiers in immunology 13, 1012016-, 2023
102023
The emerging roles of the gut microbiome in allogeneic hematopoietic stem cell transplantation
LT Khuat, M Dave, WJ Murphy
Gut microbes 13 (1), 1966262, 2021
102021
Increased efficacy of dual proinflammatory cytokine blockade on acute GVHD while maintaining GVT effects
LT Khuat, LV Vick, C Dunai, CP Collins, SK More, CT Le, CCS Pai, ...
Blood, The Journal of the American Society of Hematology 138 (24), 2583-2588, 2021
92021
Obesity results in higher PD-1-mediated T-cell suppression but greater T-cell effector functions following blockade.
RJ Canter, E Aguilar, Z Wang, C Le, L Khuat, C Dunai, R Rebhun, ...
Journal of Clinical Oncology 36 (5_suppl), 65-65, 2018
62018
MSCs mediate long-term efficacy in a Crohn’s disease model by sustained anti-inflammatory macrophage programming via efferocytosis
M Dave, A Dev, RA Somoza, N Zhao, S Viswanath, PR Mina, P Chirra, ...
NPJ Regenerative Medicine 9 (1), 6, 2024
52024
Mouse Preclinical Cancer Immunotherapy Modeling Involving Anti-PD-1 Therapies Reveals the Need to Use Mouse Reagents to Mirror Clinical Paradigms
AM Monjazeb, Z Wang, LV Vick, C Dunai, C Minnar, LT Khuat, WJ Murphy
Cancers 13 (4), 729, 2021
52021
Regulation of human and mouse bystander T cell activation responses by PD-1
CT Le, LV Vick, C Collins, C Dunai, MK Sheng, LT Khuat, I Barao, ...
JCI insight 8 (18), 2023
42023
Mesenchymal stem cells ameliorate inflammation in an experimental model of Crohn's disease via the mesentery
M Dave, A Dev, RA Somoza, N Zhao, S Viswanath, PR Mina, P Chirra, ...
bioRxiv, 2023.05. 22.541829, 2023
22023
Activation status dictates the function of unlicensed natural killer cells in mice and humans
EG Aguilar, C Dunai, SJ Judge, AE Zamora, LT Khuat, LV Vick, CP Collins, ...
Blood Advances 5 (20), 4219-4232, 2021
22021
Systemic Immunostimulation Induces Glucocorticoid-Mediated Thymic Involution Succeeded By Rebound Hyperplasia Which is Impaired In Aged Recipients
C Collins, LT Khuat, G Turner, LV Vick, CM Minnar, C Dunai, CK Le, ...
Frontiers in Immunology 15, 1429912, 0
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