| A community effort to assess and improve drug sensitivity prediction algorithms JC Costello, LM Heiser, E Georgii, M Gönen, MP Menden, NJ Wang, ... Nature biotechnology 32 (12), 1202-1212, 2014 | 760 | 2014 |
| Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection AD Ewing, KE Houlahan, Y Hu, K Ellrott, C Caloian, TN Yamaguchi, ... Nature methods 12 (7), 623-630, 2015 | 321 | 2015 |
| Toward selective histone deacetylase inhibitor design: homology modeling, docking studies, and molecular dynamics simulations of human class I histone deacetylases DF Wang, P Helquist, NL Wiech, O Wiest Journal of medicinal chemistry 48 (22), 6936-6947, 2005 | 261 | 2005 |
| pH-Controlled Hydrogen Sulfide Release for Myocardial Ischemia-Reperfusion Injury J Kang, Z Li, CL Organ, CM Park, C Yang, A Pacheco, D Wang, DJ Lefer, ... Journal of the American Chemical Society 138 (20), 6336-6339, 2016 | 234 | 2016 |
| On the function of the 14 Å long internal cavity of histone deacetylase-like protein: implications for the design of histone deacetylase inhibitors DF Wang, O Wiest, P Helquist, HY Lan-Hargest, NL Wiech Journal of medicinal chemistry 47 (13), 3409-3417, 2004 | 186 | 2004 |
| A General Strategy for Development of Near‐Infrared Fluorescent Probes for Bioimaging W Chen, S Xu, JJ Day, D Wang, M Xian Angewandte Chemie 129, 16838-16842, 2017 | 179 | 2017 |
| Prediction of overall survival for patients with metastatic castration-resistant prostate cancer: development of a prognostic model through a crowdsourced challenge with open … J Guinney, T Wang, TD Laajala, KK Winner, JC Bare, EC Neto, SA Khan, ... Lancet Oncology 18 (1), 132-142, 2017 | 161 | 2017 |
| Thailandepsins: bacterial products with potent histone deacetylase inhibitory activities and broad-spectrum antiproliferative activities C Wang, LM Henkes, LB Doughty, M He, D Wang, FJ Meyer-Almes, ... Journal of natural products 74 (10), 2031-2038, 2011 | 140 | 2011 |
| Conformational features and anion-binding properties of calix [4] pyrrole: A theoretical study YD Wu, DF Wang, JL Sessler The Journal of organic chemistry 66 (11), 3739-3746, 2001 | 133 | 2001 |
| PGC1a Promoter Methylation in Parkinson’s Disease X Su, Y Chu, JH Kordower, B Li, H Cao, L Huang, M Nishida, L Song, ... PLoS ONE 10, e0134087, 2015 | 118 | 2015 |
| Equilibrium acidities and homolytic bond dissociation energies (BDEs) of the acidic HN bonds in hydrazines and hydrazides Y Zhao, FG Bordwell, JP Cheng, D Wang Journal of the American Chemical Society 119 (39), 9125-9129, 1997 | 93 | 1997 |
| First demonstration of antigen induced cytokine expression by CD4-1+ lymphocytes in a poikilotherm: Studies in zebrafish (Danio rerio) S Yoon, S Mitra, C Wyse, A Alnabulsi, J Zou, EM Weerdenburg, ... PLoS ONE 10 (6), e0126378, 2015 | 91 | 2015 |
| Zinc binding in HDAC inhibitors: a DFT study D Wang, P Helquist, O Wiest The Journal of organic chemistry 72 (14), 5446-5449, 2007 | 74 | 2007 |
| Whole genome sequencing of skull-base chordoma reveals genomic alterations associated with recurrence and chordoma-specific survival J Bai, J Shi, C Li, S Wang, T Zhang, X Hua, B Zhu, H Koka, HH Wu, ... Nature communications 12 (1), 1-13, 2021 | 65 | 2021 |
| Immune gene expression profiling reveals heterogeneity in luminal breast tumors B Zhu, LA Tse, D Wang, H Koka, T Zhang, M Abubakar, P Lee, F Wang, ... Breast Cancer Research 21 (1), 1-11, 2019 | 59 | 2019 |
| QSAR studies of PC-3 cell line inhibition activity of TSA and SAHA-like hydroxamic acids DF Wang, O Wiest, P Helquist, HY Lan-Hargest, NL Wiech Bioorganic & medicinal chemistry letters 14 (3), 707-711, 2004 | 59 | 2004 |
| Computational studies on the histone deacetylases and the design of selective histone deacetylase inhibitors D Wang Current topics in medicinal chemistry 9 (3), 241, 2009 | 58 | 2009 |
| Sequence-dependent Kink-and-Slide deformations of nucleosomal DNA facilitated by histone arginines bound in the minor groove D Wang, NB Ulyanov, VB Zhurkin Journal of Biomolecular Structure and Dynamics 27 (6), 843-859, 2010 | 50 | 2010 |
| p53 binding to nucleosomal DNA depends on the rotational positioning of DNA response element G Sahu, D Wang, CB Chen, VB Zhurkin, RE Harrington, E Appella, ... Journal of biological chemistry 285 (2), 1321-1332, 2010 | 48 | 2010 |
| Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection AY Lee, AD Ewing, K Ellrott, Y Hu, KE Houlahan, JC Bare, SMG Espiritu, ... Genome biology 19 (1), 188, 2018 | 47 | 2018 |
