Follow
Henry Pelish
Henry Pelish
Unknown affiliation
No verified email
Title
Cited by
Cited by
Year
Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosis
T Kirchhausen, E Macia, HE Pelish
Methods in enzymology 438, 77-93, 2008
4882008
Mediator kinase inhibition further activates super-enhancer-associated genes in AML
HE Pelish, BB Liau, II Nitulescu, A Tangpeerachaikul, ZC Poss, ...
Nature 526 (7572), 273-276, 2015
3672015
Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product
HE Pelish, NJ Westwood, Y Feng, T Kirchhausen, MD Shair
Journal of the American chemical society 123 (27), 6740-6741, 2001
2922001
Secramine inhibits Cdc42-dependent functions in cells and Cdc42 activation in vitro
HE Pelish, JR Peterson, SB Salvarezza, E Rodriguez-Boulan, JL Chen, ...
Nature chemical biology 2 (1), 39-46, 2006
1962006
Identification of mediator kinase substrates in human cells using cortistatin A and quantitative phosphoproteomics
ZC Poss, CC Ebmeier, AT Odell, A Tangpeerachaikul, T Lee, HE Pelish, ...
Cell reports 15 (2), 436-450, 2016
1422016
An alkylsilyl-tethered, high-capacity solid support amenable to diversity-oriented synthesis for one-bead, one-stock solution chemical genetics
JA Tallarico, KM Depew, HE Pelish, NJ Westwood, CW Lindsley, ...
Journal of combinatorial chemistry 3 (3), 312-318, 2001
1362001
Biochemical suppression of small-molecule inhibitors: a strategy to identify inhibitor targets and signaling pathway components
JR Peterson, AM Lebensohn, HE Pelish, MW Kirschner
Chemistry & biology 13 (4), 443-452, 2006
822006
The selectivity of austocystin D arises from cell-line-specific drug activation by cytochrome P450 enzymes
KM Marks, ES Park, A Arefolov, K Russo, K Ishihara, JE Ring, J Clardy, ...
Journal of natural products 74 (4), 567-573, 2011
482011
Mediator kinase phosphorylation of STAT1 S727 promotes growth of neoplasms with JAK-STAT activation
II Nitulescu, SC Meyer, QJ Wen, JD Crispino, ME Lemieux, RL Levine, ...
EBioMedicine 26, 112-125, 2017
462017
NUV-655 (NVL-655) is a selective, brain-penetrant ALK inhibitor with antitumor activity against the lorlatinib-resistant G1202R/L1196M compound mutation
HE Pelish, A Tangpeerachaikul, NE Kohl, JR Porter, MD Shair, JC Horan
Cancer Research 81 (13_Supplement), 1468-1468, 2021
332021
Large scale synthesis of the Cdc42 inhibitor secramine A and its inhibition of cell spreading
B Xu, H Pelish, T Kirchhausen, GB Hammond
Organic & biomolecular chemistry 4 (22), 4149-4157, 2006
312006
STAT3 inhibitory activity of structurally simplified withaferin A analogues
T Tahara, U Streit, HE Pelish, MD Shair
Organic letters 19 (7), 1538-1541, 2017
192017
The Cdc42 inhibitor secramine B prevents cAMP-induced K+ conductance in intestinal epithelial cells
HE Pelish, W Ciesla, N Tanaka, K Reddy, MD Shair, T Kirchhausen, ...
Biochemical pharmacology 71 (12), 1720-1726, 2006
152006
NVL-520 is a selective, TRK-sparing, and brain-penetrant inhibitor of ROS1 fusions and secondary resistance mutations
A Drilon, JC Horan, A Tangpeerachaikul, B Besse, SHI Ou, SM Gadgeel, ...
Cancer discovery 13 (3), 598-615, 2023
142023
NUV-520 (NVL-520) is a brain-penetrant and highly selective ROS1 inhibitor with antitumor activity against the G2032R solvent front mutation
HE Pelish, A Tangpeerachaikul, NE Kohl, JR Porter, MD Shair, JC Horan
Cancer Research 81 (13_Supplement), 1465-1465, 2021
42021
Alkaloids
M Shair, N Westwood, HE Pelish
US Patent 6,797,819, 2004
42004
Preclinical activity of NVL-655 in ALK-driven cancer models beyond non-small cell lung cancer
A Tangpeerachaikul, L Bigot, L Friboulet, HE Pelish
Cancer Res 82 (12_Supplement), 3337, 2022
32022
Abstract P244: NVL-655 exhibits antitumor activity in lorlatinib-resistant and intracranial models of ALK-rearranged NSCLC
A Tangpeerachaikul, A Deshpande, NE Kohl, JC Horan, HE Pelish
Molecular Cancer Therapeutics 20 (12_Supplement), P244-P244, 2021
32021
PRPK-TPRKB modulators and uses thereof
ES Park, HE Pelish, AS Clarke, GL Williams, MP Castaldi, A Arefolov, ...
US Patent 9,193,989, 2015
32015
Biomimetic combinatorial synthesis
M Shair, C Lindsley, H Pelish, S Sheehan, B Goess, M Layton, L Chan, ...
US Patent App. 09/838,760, 2001
32001
The system can't perform the operation now. Try again later.
Articles 1–20