ARB-1740, a RNA interference therapeutic for chronic hepatitis B infection EP Thi, AP Dhillon, A Ardzinski, L Bidirici-Ertekin, KD Cobarrubias, ... ACS Infectious Diseases 5 (5), 725-737, 2018 | 48 | 2018 |
Design of potent antimalarials with generative chemistry WJ Godinez, EJ Ma, AT Chao, L Pei, P Skewes-Cox, SM Canham, ... Nature Machine Intelligence 4 (2), 180-186, 2022 | 24 | 2022 |
Discovery and preclinical pharmacology of INE963, a potent and fast-acting blood-stage antimalarial with a high barrier to resistance and potential for single-dose cures in … BR Taft, F Yokokawa, T Kirrane, AC Mata, R Huang, N Blaquiere, ... Journal of Medicinal Chemistry 65 (5), 3798-3813, 2022 | 15 | 2022 |
In vivo study of a LNP siRNA investigational agent applied sequentially with immunomodulatory treatments for chronic hepatitis B infection EP Thi, H Huang, L Pei, X Ye, A Miller, AH Li, A Jarosz, S Majeski, JJ Park, ... Hepatology 66, 497A-497A, 2017 | 4 | 2017 |
Development of second generation RNA interference therapy for hepatitis B virus infection EP Thi, X Ye, AP Dhillon, NM Snead, AS Kondratowicz, L Pei, ... Hepatology 63 (1 SUPP), 922A-922A, 2016 | 4 | 2016 |
Identification and characterization of HBV RNA destabilizers in vitro and in vivo D Gotchev, M Gao, C Moore, AS Kondratowicz, C Abbott, L Bailey, Y Bi, ... Hepatology 66, 493A-494A, 2017 | 3 | 2017 |
Compound activity prediction with dose-dependent transcriptomic profiles and deep learning WJ Godinez, V Trifonov, B Fang, G Kuzu, L Pei, WA Guiguemde, ... Journal of Chemical Information and Modeling, 2024 | 2 | 2024 |
TKM-HBV, a novel RNA interference treatment for chronic hepatitis B, rapidly reduces surface antigen and other viral proteins in both intrahepatic and peripheral compartments AC Lee, EP Thi, L Pei, X Ye, J Cross, SY Du, AP Dhillon, JR Phelps, ... Hepatology 62, 1186A-1186A, 2015 | 2 | 2015 |
JAEGER–Hunting for Antimalarials with Generative Chemistry W Godinez, E Ma, A Chao, L Pei, P Skewes-Cox, S Canham, J Jenkins, ... | 1 | 2021 |