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Luying Pei
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ARB-1740, a RNA interference therapeutic for chronic hepatitis B infection
EP Thi, AP Dhillon, A Ardzinski, L Bidirici-Ertekin, KD Cobarrubias, ...
ACS Infectious Diseases 5 (5), 725-737, 2018
482018
Design of potent antimalarials with generative chemistry
WJ Godinez, EJ Ma, AT Chao, L Pei, P Skewes-Cox, SM Canham, ...
Nature Machine Intelligence 4 (2), 180-186, 2022
242022
Discovery and preclinical pharmacology of INE963, a potent and fast-acting blood-stage antimalarial with a high barrier to resistance and potential for single-dose cures in …
BR Taft, F Yokokawa, T Kirrane, AC Mata, R Huang, N Blaquiere, ...
Journal of Medicinal Chemistry 65 (5), 3798-3813, 2022
152022
In vivo study of a LNP siRNA investigational agent applied sequentially with immunomodulatory treatments for chronic hepatitis B infection
EP Thi, H Huang, L Pei, X Ye, A Miller, AH Li, A Jarosz, S Majeski, JJ Park, ...
Hepatology 66, 497A-497A, 2017
42017
Development of second generation RNA interference therapy for hepatitis B virus infection
EP Thi, X Ye, AP Dhillon, NM Snead, AS Kondratowicz, L Pei, ...
Hepatology 63 (1 SUPP), 922A-922A, 2016
42016
Identification and characterization of HBV RNA destabilizers in vitro and in vivo
D Gotchev, M Gao, C Moore, AS Kondratowicz, C Abbott, L Bailey, Y Bi, ...
Hepatology 66, 493A-494A, 2017
32017
Compound activity prediction with dose-dependent transcriptomic profiles and deep learning
WJ Godinez, V Trifonov, B Fang, G Kuzu, L Pei, WA Guiguemde, ...
Journal of Chemical Information and Modeling, 2024
22024
TKM-HBV, a novel RNA interference treatment for chronic hepatitis B, rapidly reduces surface antigen and other viral proteins in both intrahepatic and peripheral compartments
AC Lee, EP Thi, L Pei, X Ye, J Cross, SY Du, AP Dhillon, JR Phelps, ...
Hepatology 62, 1186A-1186A, 2015
22015
JAEGER–Hunting for Antimalarials with Generative Chemistry
W Godinez, E Ma, A Chao, L Pei, P Skewes-Cox, S Canham, J Jenkins, ...
12021
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Articles 1–9