David Schaffer
David Schaffer
Professor of Chemical and Biomolecular Engineering, Bioengineering, and Neuroscience, UC Berkeley
Verified email at - Homepage
Cited by
Cited by
Substrate modulus directs neural stem cell behavior
K Saha, AJ Keung, EF Irwin, Y Li, L Little, DV Schaffer, KE Healy
Biophysical journal 95 (9), 4426-4438, 2008
A designer AAV variant permits efficient retrograde access to projection neurons
DGR Tervo, BY Hwang, S Viswanathan, T Gaj, M Lavzin, KD Ritola, ...
Neuron 92 (2), 372-382, 2016
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
K Lai, BK Kaspar, FH Gage, DV Schaffer
Nature neuroscience 6 (1), 21-27, 2003
Engineering adeno-associated viruses for clinical gene therapy
MA Kotterman, DV Schaffer
Nature Reviews Genetics 15 (7), 445-451, 2014
In vivo–directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous
D Dalkara, LC Byrne, RR Klimczak, M Visel, L Yin, WH Merigan, ...
Science translational medicine 5 (189), 189ra76-189ra76, 2013
The influence of hydrogel modulus on the proliferation and differentiation of encapsulated neural stem cells
A Banerjee, M Arha, S Choudhary, RS Ashton, SR Bhatia, DV Schaffer, ...
Biomaterials 30 (27), 4695-4699, 2009
Stochastic gene expression in a lentiviral positive-feedback loop: HIV-1 Tat fluctuations drive phenotypic diversity
LS Weinberger, JC Burnett, JE Toettcher, AP Arkin, DV Schaffer
Cell 122 (2), 169-182, 2005
Vector unpacking as a potential barrier for receptor‐mediated polyplex gene delivery
DV Schaffer, NA Fidelman, N Dan, DA Lauffenburger
Biotechnology and bioengineering 67 (5), 598-606, 2000
Directed evolution of adeno-associated virus yields enhanced gene delivery vectors
N Maheshri, JT Koerber, BK Kaspar, DV Schaffer
Nature biotechnology 24 (2), 198-204, 2006
The AAV vector toolkit: poised at the clinical crossroads
A Asokan, DV Schaffer, RJ Samulski
Molecular Therapy 20 (4), 699-708, 2012
Biophysical regulation of epigenetic state and cell reprogramming
TL Downing, J Soto, C Morez, T Houssin, A Fritz, F Yuan, J Chu, S Patel, ...
Nature materials 12 (12), 1154-1162, 2013
Viral vectors for gene therapy: translational and clinical outlook
MA Kotterman, TW Chalberg, DV Schaffer
Annual review of biomedical engineering 17, 63-89, 2015
Optogenetic protein clustering and signaling activation in mammalian cells
LJ Bugaj, AT Choksi, CK Mesuda, RS Kane, DV Schaffer
Nature methods 10 (3), 249-252, 2013
PI3K/Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiation
J Peltier, A O'Neill, DV Schaffer
Developmental neurobiology 67 (10), 1348-1361, 2007
Single-cell western blotting
AJ Hughes, DP Spelke, Z Xu, CC Kang, DV Schaffer, AE Herr
Nature methods 11 (7), 749-755, 2014
Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous
D Dalkara, KD Kolstad, N Caporale, M Visel, RR Klimczak, DV Schaffer, ...
Molecular Therapy 17 (12), 2096-2102, 2009
A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation
Y Lei, DV Schaffer
Proceedings of the National Academy of Sciences 110 (52), E5039-E5048, 2013
X‐space MPI: magnetic nanoparticles for safe medical imaging
PW Goodwill, EU Saritas, LR Croft, TN Kim, KM Krishnan, DV Schaffer, ...
Advanced materials 24 (28), 3870-3877, 2012
Quantitative magnetic particle imaging monitors the transplantation, biodistribution, and clearance of stem cells in vivo
B Zheng, MP von See, E Yu, B Gunel, K Lu, T Vazin, DV Schaffer, ...
Theranostics 6 (3), 291, 2016
Transforming growth factor-β and notch signaling mediate stem cell differentiation into smooth muscle cells
K Kurpinski, H Lam, J Chu, A Wang, A Kim, E Tsay, S Agrawal, ...
Stem cells 28 (4), 734-742, 2010
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