Leader β-cells coordinate Ca2+ dynamics across pancreatic islets in vivo V Salem, LD Silva, K Suba, E Georgiadou, S Neda Mousavy Gharavy, ... Nature Metabolism 1 (6), 615-629, 2019 | 141 | 2019 |
The effects of kisspeptin on β‐cell function, serum metabolites and appetite in humans C Izzi‐Engbeaya, AN Comninos, SA Clarke, A Jomard, L Yang, S Jones, ... Diabetes, Obesity and Metabolism 20 (12), 2800-2810, 2018 | 100 | 2018 |
β‐arrestin1 phosphorylation by GRK5 regulates G protein‐independent 5‐HT4 receptor signalling G Barthet, G Carrat, E Cassier, B Barker, F Gaven, M Pillot, B Framery, ... The EMBO journal 28 (18), 2706-2718, 2009 | 86 | 2009 |
Persistent or transient human β cell dysfunction induced by metabolic stress: specific signatures and shared gene expression with type 2 diabetes L Marselli, A Piron, M Suleiman, ML Colli, X Yi, A Khamis, GR Carrat, ... Cell Reports 33 (9), 2020 | 81 | 2020 |
Hyperglycemia-induced changes in ZIP7 and ZnT7 expression cause Zn2+ release from the sarco (endo) plasmic reticulum and mediate ER stress in the heart E Tuncay, VC Bitirim, A Durak, GRJ Carrat, KM Taylor, GA Rutter, B Turan Diabetes 66 (5), 1346-1358, 2017 | 79 | 2017 |
Decreased STARD10 expression is associated with defective insulin secretion in humans and mice GR Carrat, M Hu, MS Nguyen-Tu, P Chabosseau, KJ Gaulton, ... The American Journal of Human Genetics 100 (2), 238-256, 2017 | 67 | 2017 |
Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity S Kleiner, D Gomez, B Megra, E Na, R Bhavsar, K Cavino, Y Xin, J Rojas, ... Proceedings of the National Academy of Sciences 115 (32), E7642-E7649, 2018 | 60 | 2018 |
Constitutive activity of serotonin2C receptors at G protein-independent signaling: modulation by RNA editing and antidepressants M Labasque, J Meffre, G Carrat, C Becamel, J Bockaert, P Marin Molecular pharmacology 78 (5), 818-826, 2010 | 55 | 2010 |
The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis GR Carrat, E Haythorne, A Tomas, L Haataja, A Müller, P Arvan, A Piunti, ... Molecular metabolism 40, 101015, 2020 | 23 | 2020 |
Hypothalamic arcuate nucleus glucokinase regulates insulin secretion and glucose homeostasis Y Ma, R Ratnasabapathy, C Izzi‐Engbeaya, MS Nguyen‐Tu, ... Diabetes, Obesity and Metabolism 20 (9), 2246-2254, 2018 | 14 | 2018 |
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion M Hu, I Cebola, G Carrat, S Jiang, S Nawaz, A Khamis, M Canouil, ... Cell reports 34 (5), 2021 | 10 | 2021 |
In vivo and in vitro characterization of GL0034, a novel long‐acting glucagon‐like peptide‐1 receptor agonist B Jones, V Burade, E Akalestou, Y Manchanda, Z Ramchunder, G Carrat, ... Diabetes, Obesity and Metabolism 24 (11), 2090-2101, 2022 | 3 | 2022 |
87-LB: binding kinetics, bias, receptor internalization, and effects on insulin secretion for a novel GLP1R-GIPR dual agonist, HISHS-2001 Y Manchanda, B Jones, G Carrat, Z Ramchunder, P Marchetti, I Leclerc, ... Diabetes 70 (Supplement_1), 2021 | 2 | 2021 |
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a new regulator of insulin secretion M Hu, I Cebola, G Carrat, S Jiang, S Nawaz, A Khamis, M Canouil, ... bioRxiv, 2020.03. 31.017707, 2020 | 2 | 2020 |
Kisspeptin stimulates insulin secretion and modulates serum metabolites in humans EC Izzi, AN Comninos, SA Clarke, A Jomard, L Yang, S Jones, A Abbara, ... Endocrine Abstracts 59, 2018 | 1 | 2018 |
Real-time In vivo imaging of whole islet Ca2+ dynamics reveals glucose-induced changes in beta-cell connectivity in mouse and human islets V Salem, K Suba, A ALONSO, PL Chabosseau, E Georgiadou, ... Diabetes 67 (Supplement_1), 2018 | 1 | 2018 |
Roles of the Type 2 diabetes associated gene products Arap1 and StarD10 in the control of insulin secretion G Carrat, G Meur, GA Rutter DIABETIC MEDICINE 30, 31-31, 2013 | 1 | 2013 |
In vivo and in vitro characterisation of GL0034, a novel long-acting GLP-1 receptor agonist B Jones, V Burade, E Akalestou, Y Manchanda, Z Ramchunder, G Carrat, ... DIABETES, OBESITY AND METABOLISM, 2022 | | 2022 |
The type 2 diabetes-associated lipid-binding protein STARD10 could bind phosphatidylinositides and affect islet lipid composition G Carrat, L Haataja, P Arvan, A Tomas, K Cheng, NS Amirruddin, ... DIABETIC MEDICINE 37, 39-39, 2020 | | 2020 |
Pancreatic beta cell-selective deletion of themitofusins 1 and 2 (Mfn1 and Mfn2) impairs glucose-stimulated insulin secretion in vitro and in vivo GA Rutter, E Georgiadou, T Rodriguez, C Muralidharan, M Martinez, ... DIABETOLOGIA 63 (SUPPL 1), S6-S7, 2020 | | 2020 |