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Gaëlle Carrat
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Leader β-cells coordinate Ca2+ dynamics across pancreatic islets in vivo
V Salem, LD Silva, K Suba, E Georgiadou, S Neda Mousavy Gharavy, ...
Nature Metabolism 1 (6), 615-629, 2019
1412019
The effects of kisspeptin on β‐cell function, serum metabolites and appetite in humans
C Izzi‐Engbeaya, AN Comninos, SA Clarke, A Jomard, L Yang, S Jones, ...
Diabetes, Obesity and Metabolism 20 (12), 2800-2810, 2018
1002018
β‐arrestin1 phosphorylation by GRK5 regulates G protein‐independent 5‐HT4 receptor signalling
G Barthet, G Carrat, E Cassier, B Barker, F Gaven, M Pillot, B Framery, ...
The EMBO journal 28 (18), 2706-2718, 2009
862009
Persistent or transient human β cell dysfunction induced by metabolic stress: specific signatures and shared gene expression with type 2 diabetes
L Marselli, A Piron, M Suleiman, ML Colli, X Yi, A Khamis, GR Carrat, ...
Cell Reports 33 (9), 2020
812020
Hyperglycemia-induced changes in ZIP7 and ZnT7 expression cause Zn2+ release from the sarco (endo) plasmic reticulum and mediate ER stress in the heart
E Tuncay, VC Bitirim, A Durak, GRJ Carrat, KM Taylor, GA Rutter, B Turan
Diabetes 66 (5), 1346-1358, 2017
792017
Decreased STARD10 expression is associated with defective insulin secretion in humans and mice
GR Carrat, M Hu, MS Nguyen-Tu, P Chabosseau, KJ Gaulton, ...
The American Journal of Human Genetics 100 (2), 238-256, 2017
672017
Mice harboring the human SLC30A8 R138X loss-of-function mutation have increased insulin secretory capacity
S Kleiner, D Gomez, B Megra, E Na, R Bhavsar, K Cavino, Y Xin, J Rojas, ...
Proceedings of the National Academy of Sciences 115 (32), E7642-E7649, 2018
602018
Constitutive activity of serotonin2C receptors at G protein-independent signaling: modulation by RNA editing and antidepressants
M Labasque, J Meffre, G Carrat, C Becamel, J Bockaert, P Marin
Molecular pharmacology 78 (5), 818-826, 2010
552010
The type 2 diabetes gene product STARD10 is a phosphoinositide-binding protein that controls insulin secretory granule biogenesis
GR Carrat, E Haythorne, A Tomas, L Haataja, A Müller, P Arvan, A Piunti, ...
Molecular metabolism 40, 101015, 2020
232020
Hypothalamic arcuate nucleus glucokinase regulates insulin secretion and glucose homeostasis
Y Ma, R Ratnasabapathy, C Izzi‐Engbeaya, MS Nguyen‐Tu, ...
Diabetes, Obesity and Metabolism 20 (9), 2246-2254, 2018
142018
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a regulator of insulin secretion
M Hu, I Cebola, G Carrat, S Jiang, S Nawaz, A Khamis, M Canouil, ...
Cell reports 34 (5), 2021
102021
In vivo and in vitro characterization of GL0034, a novel long‐acting glucagon‐like peptide‐1 receptor agonist
B Jones, V Burade, E Akalestou, Y Manchanda, Z Ramchunder, G Carrat, ...
Diabetes, Obesity and Metabolism 24 (11), 2090-2101, 2022
32022
87-LB: binding kinetics, bias, receptor internalization, and effects on insulin secretion for a novel GLP1R-GIPR dual agonist, HISHS-2001
Y Manchanda, B Jones, G Carrat, Z Ramchunder, P Marchetti, I Leclerc, ...
Diabetes 70 (Supplement_1), 2021
22021
Chromatin 3D interaction analysis of the STARD10 locus unveils FCHSD2 as a new regulator of insulin secretion
M Hu, I Cebola, G Carrat, S Jiang, S Nawaz, A Khamis, M Canouil, ...
bioRxiv, 2020.03. 31.017707, 2020
22020
Kisspeptin stimulates insulin secretion and modulates serum metabolites in humans
EC Izzi, AN Comninos, SA Clarke, A Jomard, L Yang, S Jones, A Abbara, ...
Endocrine Abstracts 59, 2018
12018
Real-time In vivo imaging of whole islet Ca2+ dynamics reveals glucose-induced changes in beta-cell connectivity in mouse and human islets
V Salem, K Suba, A ALONSO, PL Chabosseau, E Georgiadou, ...
Diabetes 67 (Supplement_1), 2018
12018
Roles of the Type 2 diabetes associated gene products Arap1 and StarD10 in the control of insulin secretion
G Carrat, G Meur, GA Rutter
DIABETIC MEDICINE 30, 31-31, 2013
12013
In vivo and in vitro characterisation of GL0034, a novel long-acting GLP-1 receptor agonist
B Jones, V Burade, E Akalestou, Y Manchanda, Z Ramchunder, G Carrat, ...
DIABETES, OBESITY AND METABOLISM, 2022
2022
The type 2 diabetes-associated lipid-binding protein STARD10 could bind phosphatidylinositides and affect islet lipid composition
G Carrat, L Haataja, P Arvan, A Tomas, K Cheng, NS Amirruddin, ...
DIABETIC MEDICINE 37, 39-39, 2020
2020
Pancreatic beta cell-selective deletion of themitofusins 1 and 2 (Mfn1 and Mfn2) impairs glucose-stimulated insulin secretion in vitro and in vivo
GA Rutter, E Georgiadou, T Rodriguez, C Muralidharan, M Martinez, ...
DIABETOLOGIA 63 (SUPPL 1), S6-S7, 2020
2020
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