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Christel Claes
Christel Claes
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Year
Development of a chimeric model to study and manipulate human microglia in vivo
J Hasselmann, MA Coburn, W England, DXF Velez, SK Shabestari, ...
Neuron 103 (6), 1016-1033. e10, 2019
2562019
Stem-cell-derived human microglia transplanted in mouse brain to study human disease
R Mancuso, J Van Den Daele, N Fattorelli, L Wolfs, S Balusu, O Burton, ...
Nature neuroscience 22 (12), 2111-2116, 2019
2002019
Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease
C Claes, EP Danhash, J Hasselmann, JP Chadarevian, SK Shabestari, ...
Molecular neurodegeneration 16, 1-11, 2021
782021
Human stem cell–derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2
C Claes, J Van Den Daele, R Boon, S Schouteden, A Colombo, ...
Alzheimer's & Dementia 15 (3), 453-464, 2019
712019
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ...
Cell reports 39 (11), 2022
652022
Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication
N Helsen, Y Debing, J Paeshuyse, K Dallmeier, R Boon, M Coll, ...
Journal of Hepatology 64 (3), 565-573, 2016
592016
The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model
C Claes, WE England, EP Danhash, S Kiani Shabestari, A Jairaman, ...
Alzheimer's & Dementia 18 (10), 1765-1778, 2022
232022
PapRIV, a BV-2 microglial cell activating quorum sensing peptide
Y Janssens, N Debunne, A De Spiegeleer, E Wynendaele, M Planas, ...
Scientific reports 11 (1), 10723, 2021
232021
The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C
JV Pluvinage, J Sun, C Claes, RA Flynn, MS Haney, T Iram, X Meng, ...
Science translational medicine 13 (622), eabg2919, 2021
212021
Metabolic reprogramming during microglia activation
I Geric, S Schoors, C Claes, P Gressens, C Verderio, CM Verfaillie, ...
Immunometabolism 1 (1), e190002, 2019
202019
Generating tissue-resident macrophages from pluripotent stem cells: Lessons learned from microglia
C Claes, J Van den Daele, CM Verfaillie
Cellular Immunology 330, 60-67, 2018
142018
Stem cell derived human microglia transplanted in mouse brain to study genetic risk of Alzheimer’s Disease
R Mancuso, J Van Den Daele, N Fattorelli, L Wolfs, S Balusu, O Burton, ...
bioRxiv, 562561, 2019
42019
Examining the effects of the microglial PLCG2 P522R mutation by transplantation of human stem cell‐derived microglia in chimeric AD mice: Molecular and cell biology/stem cells …
C Claes, E Danhash, J Hasselmann, JP Chadarevian, SK Shabestari, ...
Alzheimer's & Dementia 16, e041539, 2020
2020
Generation of Self-Assembling 3D Neural Micro-Organoids using Human iPSC-Derived Neuronal Progenitors and Microglia
YC Chai, J Van Den Daele, C Claes, C Verfaillie
Belgian Symposium on Tissue Engineering (BSTE2018), Date: 2018/11/21-2018/11 …, 2018
2018
Unraveling the role of TREM2 mutations in Alzheimer's disease using human pluripotent stem cell-derived microglia-like cells
C Claes
2018
Induced pluripotent stem cell-derived neuronal cultures as a model to study ZIKA virus infections and antivirals
K Lanko, S Kaptein, K Eggermont, A Patel, C Claes, W Guo, ...
Tropical Medicine & International Health 22, 117-118, 2017
2017
Stem cells in neurodegeneration: mind the gap
C Claes, J Terryn, CM Verfaillie
Disease-Modifying Targets in Neurodegenerative Disorders, 81-100, 2017
2017
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Articles 1–17