Development of a chimeric model to study and manipulate human microglia in vivo J Hasselmann, MA Coburn, W England, DXF Velez, SK Shabestari, ... Neuron 103 (6), 1016-1033. e10, 2019 | 256 | 2019 |
Stem-cell-derived human microglia transplanted in mouse brain to study human disease R Mancuso, J Van Den Daele, N Fattorelli, L Wolfs, S Balusu, O Burton, ... Nature neuroscience 22 (12), 2111-2116, 2019 | 200 | 2019 |
Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease C Claes, EP Danhash, J Hasselmann, JP Chadarevian, SK Shabestari, ... Molecular neurodegeneration 16, 1-11, 2021 | 78 | 2021 |
Human stem cell–derived monocytes and microglia-like cells reveal impaired amyloid plaque clearance upon heterozygous or homozygous loss of TREM2 C Claes, J Van Den Daele, R Boon, S Schouteden, A Colombo, ... Alzheimer's & Dementia 15 (3), 453-464, 2019 | 71 | 2019 |
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ... Cell reports 39 (11), 2022 | 65 | 2022 |
Stem cell-derived hepatocytes: A novel model for hepatitis E virus replication N Helsen, Y Debing, J Paeshuyse, K Dallmeier, R Boon, M Coll, ... Journal of Hepatology 64 (3), 565-573, 2016 | 59 | 2016 |
The P522R protective variant of PLCG2 promotes the expression of antigen presentation genes by human microglia in an Alzheimer's disease mouse model C Claes, WE England, EP Danhash, S Kiani Shabestari, A Jairaman, ... Alzheimer's & Dementia 18 (10), 1765-1778, 2022 | 23 | 2022 |
PapRIV, a BV-2 microglial cell activating quorum sensing peptide Y Janssens, N Debunne, A De Spiegeleer, E Wynendaele, M Planas, ... Scientific reports 11 (1), 10723, 2021 | 23 | 2021 |
The CD22-IGF2R interaction is a therapeutic target for microglial lysosome dysfunction in Niemann-Pick type C JV Pluvinage, J Sun, C Claes, RA Flynn, MS Haney, T Iram, X Meng, ... Science translational medicine 13 (622), eabg2919, 2021 | 21 | 2021 |
Metabolic reprogramming during microglia activation I Geric, S Schoors, C Claes, P Gressens, C Verderio, CM Verfaillie, ... Immunometabolism 1 (1), e190002, 2019 | 20 | 2019 |
Generating tissue-resident macrophages from pluripotent stem cells: Lessons learned from microglia C Claes, J Van den Daele, CM Verfaillie Cellular Immunology 330, 60-67, 2018 | 14 | 2018 |
Stem cell derived human microglia transplanted in mouse brain to study genetic risk of Alzheimer’s Disease R Mancuso, J Van Den Daele, N Fattorelli, L Wolfs, S Balusu, O Burton, ... bioRxiv, 562561, 2019 | 4 | 2019 |
Examining the effects of the microglial PLCG2 P522R mutation by transplantation of human stem cell‐derived microglia in chimeric AD mice: Molecular and cell biology/stem cells … C Claes, E Danhash, J Hasselmann, JP Chadarevian, SK Shabestari, ... Alzheimer's & Dementia 16, e041539, 2020 | | 2020 |
Generation of Self-Assembling 3D Neural Micro-Organoids using Human iPSC-Derived Neuronal Progenitors and Microglia YC Chai, J Van Den Daele, C Claes, C Verfaillie Belgian Symposium on Tissue Engineering (BSTE2018), Date: 2018/11/21-2018/11 …, 2018 | | 2018 |
Unraveling the role of TREM2 mutations in Alzheimer's disease using human pluripotent stem cell-derived microglia-like cells C Claes | | 2018 |
Induced pluripotent stem cell-derived neuronal cultures as a model to study ZIKA virus infections and antivirals K Lanko, S Kaptein, K Eggermont, A Patel, C Claes, W Guo, ... Tropical Medicine & International Health 22, 117-118, 2017 | | 2017 |
Stem cells in neurodegeneration: mind the gap C Claes, J Terryn, CM Verfaillie Disease-Modifying Targets in Neurodegenerative Disorders, 81-100, 2017 | | 2017 |