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Si-Wei Zhang
Si-Wei Zhang
Verified email at wisc.edu
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Year
Rational design and synthesis of highly potent pharmacological chaperones for treatment of N370S mutant Gaucher disease
GN Wang, G Reinkensmeier, SW Zhang, J Zhou, LR Zhang, LH Zhang, ...
Journal of medicinal chemistry 52 (10), 3146-3149, 2009
852009
Cocrystals of nicotinamide and (R)-mandelic acid in many ratios with anomalous formation properties
SW Zhang, MT Harasimowicz, MM de Villiers, L Yu
Journal of the American Chemical Society 135 (50), 18981-18989, 2013
732013
Celecoxib–nicotinamide cocrystal revisited: can entropy control cocrystal formation?
SW Zhang, APJ Brunskill, E Schwartz, S Sun
Crystal Growth & Design 17 (5), 2836-2843, 2017
502017
Covalent complexes of proteasome model with peptide aldehyde inhibitors MG132 and MG101: docking and molecular dynamics study
S Zhang, Y Shi, H Jin, Z Liu, L Zhang, L Zhang
Journal of molecular modeling 15 (12), 1481-1490, 2009
422009
Hot-stage optical microscopy as an analytical tool to understand solid-state changes in pharmaceutical materials
N Stieger, M Aucamp, SW Zhang, MM De Villiers
Am. Pharm. Rev 15, 32-36, 2012
362012
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 1: Introduction and Process Overview
H Ren, KM Maloney, K Basu, MJ Di Maso, GR Humphrey, F Peng, ...
Organic Process Research & Development 24 (11), 2445-2452, 2020
292020
Formation enthalpies and polymorphs of nicotinamide–R-mandelic acid co-crystals
SW Zhang, IA Guzei, MM de Villiers, L Yu, JF Krzyzaniak
Crystal Growth & Design 12 (8), 4090-4097, 2012
282012
Synthesis of N-substituted ε-hexonolactams as pharmacological chaperones for the treatment of N370S mutant Gaucher disease
GN Wang, G Twigg, TD Butters, S Zhang, L Zhang, LH Zhang, XS Ye
Organic & biomolecular chemistry 10 (15), 2923-2927, 2012
272012
Building a better particle: Leveraging physicochemical understanding of amorphous solid dispersions and a hierarchical particle approach for improved delivery at high drug loadings
L Schenck, AKP Mann, Z Liu, M Milewski, S Zhang, J Ren, K Dewitt, ...
International journal of pharmaceutics 559, 147-155, 2019
232019
Synthesis and biological evaluation of novel 2-arylalkylthio-4-amino-6-benzyl pyrimidines as potent HIV-1 non-nucleoside reverse transcriptase inhibitors
H Qin, C Liu, J Zhang, Y Guo, S Zhang, Z Zhang, X Wang, L Zhang, J Liu
Bioorganic & medicinal chemistry letters 20 (9), 3003-3005, 2010
202010
A Method to Evaluate the Effect of Contact with Excipients on the Surface Crystallization of Amorphous Drugs
SW Zhang, L Yu, J Huang, MA Hussain, L Derdour, F Qian, MM de Villiers
AAPS PharmSciTech 15 (6), 1516-1526, 2014
192014
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 2: Development of a Robust Process for Phenol Synthesis
F Peng, GR Humphrey, KM Maloney, D Lehnherr, M Weisel, F Lévesque, ...
Organic Process Research & Development 24 (11), 2453-2461, 2020
182020
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264). Part 5: Completion of the API Free Base via a Direct Chlorosulfonylation Process
MJ Di Maso, H Ren, SW Zhang, W Liu, R Desmond, E Alwedi, ...
Organic Process Research & Development 24 (11), 2491-2497, 2020
122020
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264) Part 3: Development of a One-Pot Formylation–Cyclization Sequence to the …
K Basu, D Lehnherr, GE Martin, RA Desmond, Y Lam, F Peng, JYL Chung, ...
Organic Process Research & Development 24 (11), 2462-2477, 2020
112020
Co‐crystallization with Nicotinamide in Two Conformations Lowers Energy but Expands Volume
SW Zhang, J Kendrick, FJJ Leusen, L Yu
Journal of pharmaceutical sciences 103 (9), 2896-2903, 2014
112014
Development of a Green and Sustainable Manufacturing Process for Gefapixant Citrate (MK-7264). Part 6: Development of an Improved Commercial Salt Formation Process
KM Maloney, SW Zhang, AE Mohan, AY Lee, P Larpent, H Ren, ...
Organic Process Research & Development 24 (11), 2498-2504, 2020
62020
Iterative Non-Negative Matrix Factorization Filter for Blind Deconvolution in Photon/Ion Counting
SR Griffin, JA Biechele-Speziale, CJ Smith, X You-Dow, JK White, ...
Analytical chemistry 91 (8), 5286-5294, 2019
42019
Triboluminescence from Pharmaceutical Formulations
CJ Smith, SR Griffin, GS Eakins, F Deng, JK White, S Thirunahari, ...
Analytical chemistry 90 (11), 6893-6898, 2018
32018
Solid‐State Properties
SW Zhang, RF Dunn, AY Lee
Early Drug Development: Bringing a Preclinical Candidate to the Clinic 1 …, 2018
2018
Anomalous Formation Properties of Nicotinamide Co-crystals
SW Zhang, L Yu
Advances in Organic Crystal Chemistry, 337-353, 2015
2015
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Articles 1–20