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Jun Xu
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Conformational complexity and dynamics in a muscarinic receptor revealed by NMR spectroscopy
J Xu, Y Hu, J Kaindl, P Risel, H Hübner, S Maeda, X Niu, H Li, P Gmeiner, ...
Molecular cell 75 (1), 53-65. e7, 2019
692019
Activation of the α2B adrenoceptor by the sedative sympatholytic dexmedetomidine
D Yuan, Z Liu, J Kaindl, S Maeda, J Zhao, X Sun, J Xu, P Gmeiner, ...
Nature chemical biology 16 (5), 507-512, 2020
672020
Analysis of β2AR-Gs and β2AR-Gi complex formation by NMR spectroscopy
X Ma, Y Hu, H Batebi, J Heng, J Xu, X Liu, X Niu, H Li, PW Hildebrand, ...
Proceedings of the National Academy of Sciences 117 (37), 23096-23105, 2020
662020
Structure-based discovery of selective positive allosteric modulators of antagonists for the M2 muscarinic acetylcholine receptor
M Korczynska, MJ Clark, C Valant, J Xu, EV Moo, S Albold, DR Weiss, ...
Proceedings of the National Academy of Sciences 115 (10), E2419-E2428, 2018
662018
Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor
EA Fink*, J Xu*, H Hübner*, JM Braz*, P Seemann*, C Avet, V Craik, ...
Science 377 (6614), eabn7065, 2022
652022
Structural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family
HR Kim*, J Xu*, S Maeda, NM Duc, D Ahn, Y Du, KY Chung
Nature Communications 11 (1), 3160, 2020
442020
Structure and selectivity engineering of the M1 muscarinic receptor toxin complex
S Maeda, J Xu, FM N. Kadji, MJ Clark, J Zhao, N Tsutsumi, J Aoki, ...
Science 369 (6500), 161-167, 2020
392020
Cryo-EM structure of the AVP–vasopressin receptor 2–Gs signaling complex
L Wang*, J Xu*, S Cao, D Sun, H Liu, Q Lu, Z Liu, Y Du, C Zhang
Cell Research 31 (8), 932-934, 2021
262021
Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex
G Chen*, J Xu*, A Inoue, MF Schmidt, C Bai, Q Lu, P Gmeiner, Z Liu, Y Du
Nature communications 13 (1), 2375, 2022
172022
Structural insights into ligand recognition, activation, and signaling of the α2A adrenergic receptor
J Xu, S Cao, H Hübner, D Weikert, G Chen, Q Lu, D Yuan, P Gmeiner, ...
Science advances 8 (9), eabj5347, 2022
152022
Structural and dynamic insights into supra-physiological activation and allosteric modulation of a muscarinic acetylcholine receptor
J Xu, Q Wang, H Hübner, Y Hu, X Niu, H Wang, S Maeda, A Inoue, Y Tao, ...
Nature Communications 14 (1), 376, 2023
112023
Calcineurin-fusion facilitates Cryo-EM structure determination of a family A GPCR
J Xu, G Chen, H Wang, S Cao, J Heng, X Deupi, Y Du, BK Kobilka
BioRxiv, 2022.03. 27.485993, 2022
92022
Gαs slow conformational transition upon GTP binding and a novel Gαs regulator
D Ahn, D Provasi, NM Duc, J Xu, L Salas-Estrada, A Spasic, MW Yun, ...
Iscience 26 (5), 2023
32023
Molecular mechanism of muscarinic acetylcholine receptor M3 interaction with Gq
D Ham, A Inoue, J Xu, Y Du, KY Chung
Communications Biology 7 (1), 362, 2024
12024
Structural and functional characterization of the endogenous agonist for orphan receptor GPR3
G Chen, N Staffen, Z Wu, X Xu, J Pan, A Inoue, T Shi, P Gmeiner, Y Du, ...
Cell Research, 1-4, 2024
12024
Step-wise activation of a Family C GPCR
KK Kumar, H Wang, C Habrian, NR Latorraca, J Xu, ES O’Brien, C Zhang, ...
bioRxiv, 2023
12023
An allosteric ligand stabilizes distinct conformations in the M2 muscarinic acetylcholine receptor
J Xu, H Hübner, Y Hu, X Niu, P Gmeiner, C Jin, B Kobilka
bioRxiv, 2021.02. 14.431178, 2021
12021
Micromorphology characters of maca (Lepidium meyenii).
J Xu, YT Yu, KX Hou, H Liu, LJ Yu, WW Jin
Plant Science Journal 32 (1), 1-7, 2014
12014
Stepwise activation of a metabotropic glutamate receptor
K Krishna Kumar, H Wang, C Habrian, NR Latorraca, J Xu, ES O’Brien, ...
Nature, 1-6, 2024
2024
Author Correction: Cryo-EM structure of the AVP–vasopressin receptor 2–Gs signaling complex
L Wang, J Xu, S Cao, D Sun, H Liu, Q Lu, Z Liu, Y Du, C Zhang
Cell Research 32 (10), 957, 2022
2022
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