| Prospective derivation of a living organoid biobank of colorectal cancer patients M Van de Wetering, HE Francies, JM Francis, G Bounova, F Iorio, A Pronk, ... Cell 161 (4), 933-945, 2015 | 2243 | 2015 |
| In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration M Huch, C Dorrell, SF Boj, JH Van Es, VSW Li, M Van De Wetering, ... Nature 494 (7436), 247-250, 2013 | 1677 | 2013 |
| Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling W De Lau, N Barker, TY Low, BK Koo, VSW Li, H Teunissen, P Kujala, ... Nature 476 (7360), 293-297, 2011 | 1449 | 2011 |
| Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer K Wang, ST Yuen, J Xu, SP Lee, HHN Yan, ST Shi, HC Siu, S Deng, ... Nature genetics 46 (6), 573-582, 2014 | 1130 | 2014 |
| Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex VSW Li, SS Ng, PJ Boersema, TY Low, WR Karthaus, JP Gerlach, ... Cell 149 (6), 1245-1256, 2012 | 1074 | 2012 |
| Unlimited in vitro expansion of adult bi‐potent pancreas progenitors through the Lgr5/R‐spondin axis M Huch, P Bonfanti, SF Boj, T Sato, CJM Loomans, M Van De Wetering, ... The EMBO journal 32 (20), 2708-2721, 2013 | 738 | 2013 |
| Gene expression patterns of human colon tops and basal crypts and BMP antagonists as intestinal stem cell niche factors C Kosinski, VSW Li, ASY Chan, J Zhang, C Ho, WY Tsui, TL Chan, ... Proceedings of the National Academy of Sciences 104 (39), 15418-15423, 2007 | 737 | 2007 |
| A brief history of organoids C Corrò, L Novellasdemunt, VSW Li American Journal of Physiology-Cell Physiology 319 (1), C151-C165, 2020 | 422 | 2020 |
| Extracellular matrix hydrogel derived from decellularized tissues enables endodermal organoid culture GG Giobbe, C Crowley, C Luni, S Campinoti, M Khedr, K Kretzschmar, ... Nature communications 10 (1), 5658, 2019 | 391 | 2019 |
| Targeting Wnt signaling in colorectal cancer. A review in the theme: cell signaling: proteins, pathways and mechanisms L Novellasdemunt, P Antas, VSW Li American Journal of Physiology-Cell Physiology 309 (8), C511-C521, 2015 | 380 | 2015 |
| Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer TL Chan, ST Yuen, CK Kong, YW Chan, ASY Chan, WF Ng, WY Tsui, ... Nature genetics 38 (10), 1178-1183, 2006 | 380 | 2006 |
| Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon N Sasaki, N Sachs, K Wiebrands, SIJ Ellenbroek, A Fumagalli, ... Proceedings of the National Academy of Sciences 113 (37), E5399-E5407, 2016 | 354 | 2016 |
| The environmental sensor AHR protects from inflammatory damage by maintaining intestinal stem cell homeostasis and barrier integrity A Metidji, S Omenetti, S Crotta, Y Li, E Nye, E Ross, V Li, MR Maradana, ... Immunity 49 (2), 353-362. e5, 2018 | 333 | 2018 |
| Peyer's patch M cells derived from Lgr5+ stem cells require SpiB and are induced by RankL in cultured “miniguts” W de Lau, P Kujala, K Schneeberger, S Middendorp, VSW Li, N Barker, ... Molecular and cellular biology, 2012 | 277 | 2012 |
| Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand SF Boj, JH van Es, M Huch, VSW Li, A José, P Hatzis, M Mokry, ... Cell 151 (7), 1595-1607, 2012 | 255 | 2012 |
| The kinase TNIK is an essential activator of Wnt target genes T Mahmoudi, VSW Li, SS Ng, N Taouatas, RGJ Vries, S Mohammed, ... The EMBO journal 28 (21), 3329-3340, 2009 | 213 | 2009 |
| Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy M Tajan, M Hennequart, EC Cheung, F Zani, AK Hock, N Legrave, ... Nature communications 12 (1), 366, 2021 | 209 | 2021 |
| Identification of the transcription factor single-minded homologue 2 as a potential biomarker and immunotherapy target in prostate cancer MS Arredouani, B Lu, M Bhasin, M Eljanne, W Yue, JM Mosquera, ... Clinical cancer research 15 (18), 5794-5802, 2009 | 196 | 2009 |
| Intestinal stem cell niche: the extracellular matrix and cellular components L Meran, A Baulies, VSW Li Stem cells international 2017 (1), 7970385, 2017 | 184 | 2017 |
| Profiling proliferative cells and their progeny in damaged murine hearts K Kretzschmar, Y Post, M Bannier-Hélaouët, A Mattiotti, J Drost, O Basak, ... Proceedings of the National Academy of Sciences 115 (52), E12245-E12254, 2018 | 166 | 2018 |
