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Michael Knight
Michael Knight
Senior Scientist, UCB
Verified email at ucb.com
Title
Cited by
Cited by
Year
Direct evidence of the molecular basis for biological silicon transport
MJ Knight, L Senior, B Nancolas, S Ratcliffe, P Curnow
Nature Communications 7 (1), 11926, 2016
522016
Expression, purification, and reconstitution of a diatom silicon transporter
P Curnow, L Senior, MJ Knight, K Thamatrakoln, M Hildebrand, PJ Booth
Biochemistry 51 (18), 3776-3785, 2012
512012
The yeast enzyme Eht1 is an octanoyl‐CoA: ethanol acyltransferase that also functions as a thioesterase
MJ Knight, ID Bull, P Curnow
Yeast 31 (12), 463-474, 2014
502014
Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift
MJ Knight, RE Woolley, A Kwok, S Parsons, HBL Jones, CE Gulácsy, ...
Biochemical Journal 477 (18), 3599-3612, 2020
142020
The proximity of the N-and C-termini of bovine knob domains enable engineering of target specificity into polypeptide chains
A Hawkins, C Joyce, K Brady, A Hold, A Smith, M Knight, C Howard, ...
MAbs 14 (1), 2076295, 2022
112022
Discovery of a photoinduced histidine-histidine cross-link in an IgG4 antibody
T Powell, MJ Knight, J O’Hara, W Burkitt
Journal of the American Society for Mass Spectrometry 31 (6), 1233-1240, 2020
112020
A thermodynamic model for interpreting tryptophan excitation-energy-dependent fluorescence spectra provides insight into protein conformational sampling and stability
A Kwok, IS Camacho, S Winter, M Knight, RM Meade, MW Van der Kamp, ...
Frontiers in Molecular Biosciences 8, 778244, 2021
102021
Photoinduced cross-linking of formulation buffer amino acids to monoclonal antibodies
T Powell, MJ Knight, A Wood, J O'Hara, W Burkitt
European Journal of Pharmaceutics and Biopharmaceutics 160, 35-41, 2021
72021
The impact of forced degradation conditions on mAb dimer formation and subsequent influence on aggregation propensity
MJ Knight, L Floret, N Patel, J O’Hara, E Rodriguez
MAbs 14 (1), 2127172, 2022
32022
Characterization of the molecular mechanisms of silicon uptake in coccolithophores
S Ratcliffe, EM Meyer, CE Walker, M Knight, HM McNair, PG Matson, ...
Environmental Microbiology 25 (2), 315-330, 2023
22023
Computational modelling of diatom silicic acid transporters predicts a conserved fold with implications for their function and evolution
MJ Knight, BJ Hardy, GL Wheeler, P Curnow
Biochimica et Biophysica Acta (BBA)-Biomembranes 1865 (1), 184056, 2023
22023
Detection of Isopeptide Bonds in Monoclonal Antibody Aggregates
T Powell, MJ Knight, A Wood, J O’Hara, W Burkitt
Pharmaceutical Research 38, 1519-1530, 2021
12021
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