Immunotherapy in colorectal cancer: rationale, challenges and potential K Ganesh, ZK Stadler, A Cercek, RB Mendelsohn, J Shia, NH Segal, ... Nature reviews Gastroenterology & hepatology 16 (6), 361-375, 2019 | 1233 | 2019 |
Targeting metastatic cancer K Ganesh, J Massagué Nature medicine 27 (1), 34-44, 2021 | 592 | 2021 |
Assessment of a watch-and-wait strategy for rectal cancer in patients with a complete response after neoadjuvant therapy JJ Smith, P Strombom, OS Chow, CS Roxburgh, P Lynn, A Eaton, ... JAMA oncology 5 (4), e185896-e185896, 2019 | 442 | 2019 |
A rectal cancer organoid platform to study individual responses to chemoradiation K Ganesh, C Wu, KP O’Rourke, BC Szeglin, Y Zheng, CEG Sauvé, ... Nature medicine 25 (10), 1607-1614, 2019 | 369 | 2019 |
Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients B Nguyen, C Fong, A Luthra, SA Smith, RG DiNatale, S Nandakumar, ... Cell 185 (3), 563-575. e11, 2022 | 287 | 2022 |
Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization EE Er, M Valiente, K Ganesh, Y Zou, S Agrawal, J Hu, B Griscom, ... Nature cell biology 20 (8), 966-978, 2018 | 225 | 2018 |
L1CAM defines the regenerative origin of metastasis-initiating cells in colorectal cancer K Ganesh, H Basnet, Y Kaygusuz, AM Laughney, L He, R Sharma, ... Nature cancer 1 (1), 28-45, 2020 | 166 | 2020 |
Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1 SG Conticello, K Ganesh, K Xue, M Lu, C Rada, MS Neuberger Molecular cell 31 (4), 474-484, 2008 | 164 | 2008 |
Metastasis-initiating cells and ecosystems J Massague, K Ganesh Cancer discovery 11 (4), 971-994, 2021 | 161 | 2021 |
Mismatch repair–deficient rectal cancer and resistance to neoadjuvant chemotherapy A Cercek, G Dos Santos Fernandes, CS Roxburgh, K Ganesh, S Ng, ... Clinical Cancer Research 26 (13), 3271-3279, 2020 | 145 | 2020 |
Metastasis S Gerstberger, Q Jiang, K Ganesh Cell 186 (8), 1564-1579, 2023 | 123 | 2023 |
TGF-β inhibition and immunotherapy: checkmate K Ganesh, J Massagué Immunity 48 (4), 626-628, 2018 | 122 | 2018 |
A comprehensive comparison of early-onset and average-onset colorectal cancers A Cercek, WK Chatila, R Yaeger, H Walch, GDS Fernandes, A Krishnan, ... JNCI: Journal of the National Cancer Institute 113 (12), 1683-1692, 2021 | 95 | 2021 |
SMAD4 loss in colorectal cancer patients correlates with recurrence, loss of immune infiltrate, and chemoresistance I Wasserman, LH Lee, S Ogino, MR Marco, C Wu, X Chen, J Datta, ... Clinical Cancer Research 25 (6), 1948-1956, 2019 | 90 | 2019 |
Coaltered Ras/B-raf and TP53 is associated with extremes of survivorship and distinct patterns of metastasis in patients with metastatic colorectal cancer J Datta, JJ Smith, WK Chatila, JC McAuliffe, C Kandoth, E Vakiani, ... Clinical Cancer Research 26 (5), 1077-1085, 2020 | 68 | 2020 |
Phase II single-arm study of durvalumab and tremelimumab with concurrent radiotherapy in patients with mismatch repair–proficient metastatic colorectal cancer NH Segal, A Cercek, G Ku, AJ Wu, A Rimner, DN Khalil, D Reidy-Lagunes, ... Clinical Cancer Research 27 (8), 2200-2208, 2021 | 62 | 2021 |
Lymphatics act as a signaling hub to regulate intestinal stem cell activity RE Niec, T Chu, M Schernthanner, S Gur-Cohen, L Hidalgo, HA Pasolli, ... Cell stem cell 29 (7), 1067-1082. e18, 2022 | 60 | 2022 |
Lineage reversion drives WNT independence in intestinal cancer T Han, S Goswami, Y Hu, F Tang, MP Zafra, C Murphy, Z Cao, JT Poirier, ... Cancer discovery 10 (10), 1590-1609, 2020 | 59 | 2020 |
Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization H Basnet, L Tian, K Ganesh, YH Huang, DG Macalinao, E Brogi, ... Elife 8, e43627, 2019 | 58 | 2019 |
Clinical and genetic determinants of ovarian metastases from colorectal cancer K Ganesh, RH Shah, E Vakiani, GM Nash, HP Skottowe, R Yaeger, ... Cancer 123 (7), 1134-1143, 2017 | 56 | 2017 |