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Jing Pu
Jing Pu
Verified email at fudan.edu.cn
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Year
Characterization of the receptor-binding domain (RBD) of 2019 novel coronavirus: implication for development of RBD protein as a viral attachment inhibitor and vaccine
W Tai, L He, X Zhang, J Pu, D Voronin, S Jiang, Y Zhou, L Du
Cellular & molecular immunology 17 (6), 613-620, 2020
18852020
The antihistamine drugs carbinoxamine maleate and chlorpheniramine maleate exhibit potent antiviral activity against a broad spectrum of influenza viruses
W Xu, S Xia, J Pu, Q Wang, P Li, L Lu, S Jiang
Frontiers in microbiology 9, 411040, 2018
462018
Development of protein-and peptide-based HIV entry inhibitors targeting gp120 or gp41
J Pu, Q Wang, W Xu, L Lu, S Jiang
Viruses 11 (8), 705, 2019
442019
Potent MERS-CoV fusion inhibitory peptides identified from HR2 domain in spike protein of bat coronavirus HKU4
S Xia, Q Lan, J Pu, C Wang, Z Liu, W Xu, Q Wang, H Liu, S Jiang, L Lu
Viruses 11 (1), 56, 2019
322019
A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases
J Zhou, W Xu, Z Liu, C Wang, S Xia, Q Lan, Y Cai, S Su, J Pu, L Xing, ...
Acta Pharmaceutica Sinica B 12 (4), 1652-1661, 2022
282022
A five-helix-based SARS-CoV-2 fusion inhibitor targeting heptad repeat 2 domain against SARS-CoV-2 and its variants of concern
L Xing, X Xu, W Xu, Z Liu, X Shen, J Zhou, L Xu, J Pu, C Yang, Y Huang, ...
Viruses 14 (3), 597, 2022
272022
Design and Biological Evaluation of m-Xylene Thioether-Stapled Short Helical Peptides Targeting the HIV-1 gp41 Hexameric Coiled–Coil Fusion Complex
G Meng, J Pu, Y Li, A Han, Y Tian, W Xu, T Zhang, X Li, L Lu, C Wang, ...
Journal of medicinal chemistry 62 (19), 8773-8783, 2019
192019
Revisiting the mechanism of enfuvirtide and designing an analog with improved fusion inhibitory activity by targeting triple sites in gp41
W Xu, J Pu, S Su, C Hua, X Su, Q Wang, S Jiang, L Lu
AIDS 33 (10), 1545-1555, 2019
192019
A palmitic acid-conjugated, peptide-based pan-CoV fusion inhibitor potently inhibits infection of SARS-CoV-2 Omicron and other variants of concern
Q Lan, JFW Chan, W Xu, L Wang, F Jiao, G Zhang, J Pu, J Zhou, S Xia, ...
Viruses 14 (3), 549, 2022
132022
The analogs of furanyl methylidene rhodanine exhibit broad-spectrum inhibitory and inactivating activities against enveloped viruses, including SARS-CoV-2 and its variants
J Pu, X He, W Xu, C Wang, Q Lan, C Hua, K Wang, L Lu, S Jiang
Viruses 14 (3), 489, 2022
132022
A “two-birds-one-stone” approach toward the design of bifunctional human immunodeficiency virus type 1 entry inhibitors targeting the CCR5 coreceptor and gp41 N-terminal heptad …
C Wang, X Wang, H Wang, J Pu, Q Li, J Li, Y Liu, L Lu, S Jiang
Journal of Medicinal Chemistry 64 (15), 11460-11471, 2021
132021
An amphipathic peptide targeting the gp41 cytoplasmic tail kills HIV-1 virions and infected cells
Q Wang, S Su, J Xue, F Yu, J Pu, W Bi, S Xia, Y Meng, C Wang, W Yang, ...
Science Translational Medicine 12 (546), eaaz2254, 2020
92020
Viral entry inhibitors targeting six-helical bundle core against highly pathogenic enveloped viruses with class I fusion proteins
J Pu, JT Zhou, P Liu, F Yu, X He, L Lu, S Jiang
Current Medicinal Chemistry 29 (4), 700-718, 2022
82022
Rational design of a novel small-molecule HIV-1 inactivator targeting both gp120 and gp41 of HIV-1
J Pu, Y Dai, Q Wang, L Lu, J Zhang, W Xu, L Xie, S Wang, F Yu, X He, ...
Frontiers in Pharmacology 11, 613361, 2021
72021
Lipopeptide-based pan-CoV fusion inhibitors potently inhibit HIV-1 infection
Q Lan, J Pu, Y Cai, J Zhou, L Wang, F Jiao, W Xu, Q Wang, S Xia, L Lu, ...
Microbes and Infection 23 (8), 104840, 2021
22021
An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo
K Liu, M Tang, W Xu, X Meng, H Jin, M Han, J Pu, Y Li, F Jiao, R Sun, ...
Proceedings of the National Academy of Sciences 120 (25), e2207210120, 2023
12023
A dePEGylated Lipopeptide-Based Pan-Coronavirus Fusion Inhibitor Exhibits Potent and Broad-Spectrum Anti-HIV-1 Activity without Eliciting Anti-PEG Antibodies
L Xu, C Wang, W Xu, L Xing, J Zhou, J Pu, M Fu, L Lu, S Jiang, Q Wang
International Journal of Molecular Sciences 24 (11), 9779, 2023
2023
Peptide-Based HIV Entry Inhibitors
J Pu, Q Wang, S Jiang
Virus Entry Inhibitors: Stopping the Enemy at the Gate, 15-26, 2022
2022
P848 Revisiting enfuvirtide’s mechanism and designing its analog with improved activity by targeting triple sites in gp41
S Jiang, W Xu, J Pu, S Su, C Hua, X Su, Q Wang, L Lu
Sexually Transmitted Infections 95 (Suppl 1), A355-A356, 2019
2019
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Articles 1–19