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Shanmugarajan Krishnan
Shanmugarajan Krishnan
Senior Scientist, Drug Discovery, AgenusBio
Verified email at agenusbio.com
Title
Cited by
Cited by
Year
A glial signature and Wnt7 signaling regulate glioma-vascular interactions and tumor microenvironment
A Griveau, G Seano, SJ Shelton, R Kupp, A Jahangiri, K Obernier, ...
Cancer cell 33 (5), 874-889. e7, 2018
2052018
Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium
G Seano, HT Nia, KE Emblem, M Datta, J Ren, S Krishnan, J Kloepper, ...
Nature biomedical engineering 3 (3), 230-245, 2019
1542019
Targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas
Amoozgar Z, Kloepper J, Ren J, Tay RE, Kazer SW, Kiner E, Krishnan S, Posada J
Nature Communications 12 (Article number: 2582 (2021)), 2021
1142021
Modulation of cerebral endothelial cell function by TGF-β in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition
S Krishnan, E Szabo, I Burghardt, K Frei, G Tabatabai, M Weller
Oncotarget 6 (26), 22480, 2015
622015
Thymosin beta 4 gene silencing decreases stemness and invasiveness in glioblastoma
HG Wirsching, S Krishnan, AM Florea, K Frei, N Krayenbühl, ...
Brain 137 (2), 433-448, 2014
532014
Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma mouse models
M Datta, S Chatterjee, EM Perez, S Gritsch, S Roberge, M Duquette, ...
Proceedings of the National Academy of Sciences 120 (6), e2219199120, 2023
172023
Novel progranulin mutations with reduced serum-progranulin levels in frontotemporal lobar degeneration
HH Chiang, C Forsell, L Lilius, L Öijerstedt, S Thordardottir, ...
European Journal of Human Genetics 21 (11), 1260-1265, 2013
162013
Pharmacological evaluation of methanolic leaf extract of Swietenia mahagoni on acrylamide-induced neuropathic pain in rats
S Vanitha, VRK Thiagarajan, A Muthuraman, S Krishnan, A Aruna, ...
Toxicology and Industrial Health 31 (12), 1185-1194, 2015
152015
Combined blockade of VEGF, Angiopoietin-2, and PD1 reprograms glioblastoma endothelial cells into quasi-antigen-presenting cells
Z Amoozgar, J Ren, N Wang, P Andersson, GB Ferraro, S Krishnan, ...
bioRxiv, 2022.09. 03.506476, 2022
52022
470 Botensilimab, an Fc-enhanced CTLA-4 antibody, enhances innate and adaptive immune activation to promote superior anti-tumor immunity in cold and IO refractory tumors
C Delepine, D Levey, S Krishnan, KS Kim, A Sonabend, M Wilkens, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
22022
Implications of a granulocyte-high glioblastoma microenvironment in immune suppression and therapy resistance
S Krishnan, Z Amoozgar, F Dai, RK Jain
Journal of Pathology 253, 160‐173, 2021
22021
Abstract P057: targeting Treg cells with GITR activation alleviates resistance to immunotherapy in murine glioblastomas
Z Amoozgar, J Kloepper, J Ren, RE Tay, SW Kazer, E Kiner, S Krishnan, ...
Cancer Immunology Research 10 (1_Supplement), P057-P057, 2022
12022
Antigen presentation deficiency, mesenchymal differentiation, and resistance to immunotherapy in the murine syngeneic CT2A tumor model
JB Iorgulescu, N Ruthen, R Ahn, E Panagioti, PC Gokhale, M Neagu, ...
Frontiers in immunology 14, 1297932, 2023
2023
897-F Wnt inhibition improves efficacy of immune checkpoint blockade in glioblastoma
S Krishnan, S Lee, Z Amoozgar, S Subudhi, AS Kumar, J Posada, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 2), 2023
2023
Antigen presentation deficiency and mesenchymal differentiation underlie resistance to immunotherapy in the murine syngeneic CT2A tumor model
B Iorgulescu, N Ruthen, R Ahn, E Panagioti, P Gokhale, M Neagu, ...
Cancer Research 83 (7_Supplement), 2990-2990, 2023
2023
TMIC-61. LOSARTAN PREVENTS IMMUNOTHERAPY-ASSOCIATED EDEMA AND ENHANCES SURVIVAL IN GLIOBLASTOMA
M Datta, S Chatterjee, E Perez, S Gritsch, S Roberge, M Duquette, I Chen, ...
Neuro-Oncology 24 (Suppl 7), vii285, 2022
2022
907 Blockade of VEGF, angiopoietin-2, and PD1 reprograms dysfunctional endothelial cells in glioblastoma to quasi-antigen-presenting cells
Z Amoozgar, J Ren, N Wang, P Andersson, G Ferraro, S Krishnan, PJ Lei, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
2022
941 Botensilimab modulates innate and adaptive gene expression programs resulting in superior immune stimulation relative to a first-generation anti-CTLA-4 antibody
S Krishnan, J Chow, KT Soh, K Ostergard, C MacDermaid, M Van Dijk, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
2022
Losartan controls immune checkpoint blocker-induced edema and improves survival in glioblastoma
M Datta, S Chatterjee, EM Perez, S Gritsch, S Roberge, M Duquette, ...
bioRxiv, 2022.06. 28.497997, 2022
2022
OS12. 4 In vivo dynamics and targeting of vessel co-option in glioma
G Seano, A Griveau, S Shelton, S Krishnan, N Wang, J Kloepper, ...
Neuro-Oncology 21 (Suppl 3), iii23, 2019
2019
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