Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control I Barbieri, K Tzelepis, L Pandolfini, J Shi, G Millán-Zambrano, SC Robson, ... Nature 552 (7683), 126-131, 2017 | 907 | 2017 |
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia E Yankova, W Blackaby, M Albertella, J Rak, E De Braekeleer, ... Nature 593 (7860), 597-601, 2021 | 645 | 2021 |
A CRISPR dropout screen identifies genetic vulnerabilities and therapeutic targets in acute myeloid leukemia K Tzelepis, H Koike-Yusa, E De Braekeleer, Y Li, E Metzakopian, ... Cell reports 17 (4), 1193-1205, 2016 | 642 | 2016 |
The MLL recombinome of acute leukemias in 2013 C Meyer, J Hofmann, T Burmeister, D Gröger, TS Park, M Emerenciano, ... Leukemia 27 (11), 2165-2176, 2013 | 567 | 2013 |
New insights to the MLL recombinome of acute leukemias C Meyer, E Kowarz, J Hofmann, A Renneville, J Zuna, J Trka, ... Leukemia 23 (8), 1490-1499, 2009 | 517 | 2009 |
PPM1D mutations drive clonal hematopoiesis in response to cytotoxic chemotherapy JI Hsu, T Dayaram, A Tovy, E De Braekeleer, M Jeong, F Wang, J Zhang, ... Cell stem cell 23 (5), 700-713. e6, 2018 | 320 | 2018 |
ETV6 fusion genes in hematological malignancies: a review E De Braekeleer, N Douet-Guilbert, F Morel, MJ Le Bris, A Basinko, ... Leukemia research 36 (8), 945-961, 2012 | 212 | 2012 |
METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation EA Orellana, Q Liu, E Yankova, M Pirouz, E De Braekeleer, W Zhang, ... Molecular cell 81 (16), 3323-3338. e14, 2021 | 175 | 2021 |
UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs M Gozdecka, E Meduri, M Mazan, K Tzelepis, M Dudek, AJ Knights, ... Nature genetics 50 (6), 883-894, 2018 | 138 | 2018 |
ABL1 fusion genes in hematological malignancies: a review E De Braekeleer, N Douet‐Guilbert, D Rowe, N Bown, F Morel, C Berthou, ... European journal of haematology 86 (5), 361-371, 2011 | 134 | 2011 |
RARA fusion genes in acute promyelocytic leukemia: a review E De Braekeleer, N Douet-Guilbert, M De Braekeleer Expert review of hematology 7 (3), 347-357, 2014 | 124 | 2014 |
RUNX1 translocations and fusion genes in malignant hemopathies E De Braekeleer, N Douet-Guilbert, F Morel, MJ Le Bris, C Férec, ... Future oncology 7 (1), 77-91, 2011 | 104 | 2011 |
CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs MA Coelho, E De Braekeleer, M Firth, M Bista, S Lukasiak, ME Cuomo, ... Nature communications 11 (1), 4132, 2020 | 68 | 2020 |
SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 K Tzelepis, E De Braekeleer, D Aspris, I Barbieri, MS Vijayabaskar, ... Nature communications 9 (1), 5378, 2018 | 66 | 2018 |
Hox gene dysregulation in acute myeloid leukemia ED Braekeleer, N Douet-Guilbert, A Basinko, MJL Bris, F Morel, ... Future Oncology 10 (3), 475-495, 2014 | 62 | 2014 |
RUNX1 translocations in malignant hemopathies E De Braekeleer, C Ferec, M De Braekeleer Anticancer research 29 (4), 1031-1037, 2009 | 57 | 2009 |
3q26/EVI1 rearrangements in myeloid hemopathies: a cytogenetic review M De Braekeleer, MJ Le Bris, E De Braekeleer, A Basinko, F Morel, ... Future oncology 11 (11), 1675-1686, 2015 | 41 | 2015 |
A new partner gene fused to ABL1 in at (1; 9)(q24; q34)-associated B-cell acute lymphoblastic leukemia E De Braekeleer, N Douet-Guilbert, MJ Le Bris, C Berthou, F Morel, ... Leukemia 21 (10), 2220-2221, 2007 | 38 | 2007 |
Complex and cryptic chromosomal rearrangements involving the MLL gene in acute leukemia: a study of 7 patients and review of the literature E De Braekeleer, C Meyer, N Douet-Guilbert, F Morel, MJ Le Bris, ... Blood Cells, Molecules, and Diseases 44 (4), 268-274, 2010 | 36 | 2010 |
Cytogenetics in pre-B and B-cell acute lymphoblastic leukemia: a study of 208 patients diagnosed between 1981 and 2008 E De Braekeleer, A Basinko, N Douet-Guilbert, F Morel, MJ Le Bris, ... Cancer genetics and cytogenetics 200 (1), 8-15, 2010 | 34 | 2010 |