Manuel A. S. Santos

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Gabriela MouraUniversity of Aveiro, University of PortoVerified email at ua.pt
Ana Raquel SoaresiBiMED, Department of Medical Sciences, University of AveiroVerified email at ua.pt
Ana Catarina GomesExecutive Director CBR Genomics, PortugalVerified email at cbrgenomics.com
Philippe PierreGroup Leader, Research Director, CNRS, Centre d'Immunologie de Marseille LuminyVerified email at ciml.univ-mrs.fr
Rita BezerraRNA Biology Laboratory, University of AveiroVerified email at ua.pt
Raquel M SilvaUniversidade Católica Portuguesa, Centro de Investigação Interdisciplinar em Saúde (CIIS)Verified email at ucp.pt
Raquel SerucaProfessora da Fac. de Medicina, IpatimupVerified email at ipatimup.pt
Ivo GutDirector, Centro Nacional de Analisis Genomico, CNAG-CRG, Center for Genomic RegulationVerified email at cnag.crg.eu
Vera AfreixoUniversity of AveiroVerified email at ua.pt
Duccio CavalieriProfessor of Microbiology University of FlorenceVerified email at unifi.it
Evelina GattiCNRS Research Director - Centre d'Immunologie de Marseille Luminy (CIML)Verified email at ciml.univ-mrs.fr
Lluis Ribas de PouplanaICREA professor, IRB BarcelonaVerified email at irbbarcelona.org
Joel P. ArraisUniversity of CoimbraVerified email at dei.uc.pt
Rui VitorinoAuxilliary ResearcherVerified email at ua.pt
Rodrigo SantamaríaUniversidad de SalamancaVerified email at usal.es
Luigina RomaniProfessor of General PathologyVerified email at unipg.it
Maurizio CeppiVP Global Head of Translational Medicine @ iTeosVerified email at iteostherapeutics.com
Paulo GasparUniversity of Aveiro, Universidade de AveiroVerified email at ua.pt
Ana Paula Pêgoi3S - Instituto de Inovação e Investigação em Saúde / INEB - Instituto de Engenharia Biomédica /Verified email at ineb.up.pt
Gábor BalázsiHenry Laufer Professor of Physical & Quantitative Biology, Stony Brook UniversityVerified email at stonybrook.edu

Manuel A. S. Santos

University of Aveiro OR University of Kent OR University of Coimbra

Verified email at ua.pt - Homepage

Genetic code RNA modification and editing protein synthesis and aggregation genome biology experimental evolution


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Evolution of pathogenicity and sexual reproduction in eight Candida genomes G Butler, MD Rasmussen, MF Lin, MAS Santos, S Sakthikumar, CA Munro, ... Nature 459 (7247), 657-662, 2009	1096	2009
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells M Ceppi, PM Pereira, I Dunand-Sauthier, E Barras, W Reith, MA Santos, ... Proceedings of the National Academy of Sciences 106 (8), 2735, 2009	866	2009
The CUG codon is decoded in vivo as serine and not leucine in Candida albicans MAS Santos, MF Tuite Nucleic acids research 23 (9), 1481-1486, 1995	326	1995
MicroRNA expression variability in human cervical tissues PM Pereira, JP Marques, AR Soares, L Carreto, MAS Santos PloS one 5 (7), e11780, 2010	232	2010
Non‐standard translational events in Candida albicans mediated by an unusual seryl‐tRNA with a 5′‐CAG‐3′(leucine) anticodon. MA Santos, G Keith, MF Tuite The EMBO journal 12 (2), 607-616, 1993	192	1993
Comparative genomics of wild type yeast strains unveils important genome diversity L Carreto, MF Eiriz, AC Gomes, PM Pereira, D Schuller, MAS Santos BMC genomics 9 (1), 1-17, 2008	158	2008
Lack of microRNA‐101 causes E‐cadherin functional deregulation through EZH2 up‐regulation in intestinal gastric cancer J Carvalho, NC van Grieken, PM Pereira, S Sousa, M Tijssen, TE Buffart, ... The Journal of pathology 228 (1), 31-44, 2012	147	2012
Driving change: the evolution of alternative genetic codes MAS Santos, G Moura, SE Massey, MF Tuite TRENDS in Genetics 20 (2), 95-102, 2004	147	2004
Selective advantages created by codon ambiguity allowed for the evolution of an alternative genetic code in Candida spp. MAS Santos, C Cheesman, V Costa, P Moradas‐Ferreira, MF Tuite Molecular microbiology 31 (3), 937-947, 1999	146	1999
Phenotypic heterogeneity promotes adaptive evolution Z Bódi, Z Farkas, D Nevozhay, D Kalapis, V Lázár, B Csörgő, Á Nyerges, ... PLoS biology 15 (5), e2000644, 2017	143	2017
Protein mistranslation: friend or foe? LR de Pouplana, MAS Santos, JH Zhu, PJ Farabaugh, B Javid Trends in biochemical sciences 39 (8), 355-362, 2014	141	2014
Comparative evolutionary genomics unveils the molecular mechanism of reassignment of the CTG codon in Candida spp. SE Massey, G Moura, P Beltrão, R Almeida, JR Garey, MF Tuite, ... Genome research 13 (4), 544-557, 2003	140	2003
A genetic code alteration generates a proteome of high diversity in the human pathogen Candida albicans AC Gomes, I Miranda, RM Silva, GR Moura, B Thomas, A Akoulitchev, ... Genome biology 8 (10), 1-15, 2007	129	2007
Comparative context analysis of codon pairs on an ORFeome scale G Moura, M Pinheiro, R Silva, I Miranda, V Afreixo, G Dias, A Freitas, ... Genome biology 6 (3), 1-14, 2005	127	2005
Ischemic insults induce necroptotic cell death in hippocampal neurons through the up-regulation of endogenous RIP3 M Vieira, J Fernandes, L Carreto, B Anuncibay-Soto, M Santos, J Han, ... Neurobiology of disease 68, 26-36, 2014	126	2014
Large scale comparative codon-pair context analysis unveils general rules that fine-tune evolution of mRNA primary structure G Moura, M Pinheiro, J Arrais, AC Gomes, L Carreto, A Freitas, JL Oliveira, ... Plos one 2 (9), e847, 2007	116	2007
The non‐standard genetic code of Candida spp.: an evolving genetic code or a novel mechanism for adaptation? MAS Santos, T Ueda, K Watanabe, MF Tuite Molecular microbiology 26 (3), 423-431, 1997	115	1997
The genetic code of the fungal CTG clade MAS Santos, AC Gomes, MC Santos, LC Carreto, GR Moura Comptes rendus biologies 334 (8-9), 607-611, 2011	105	2011
Genetic diversity and population structure of Saccharomyces cerevisiae strains isolated from different grape varieties and winemaking regions D Schuller, F Cardoso, S Sousa, P Gomes, AC Gomes, MAS Santos, ... PloS one 7 (2), e32507, 2012	102	2012
Transfer RNA structural change is a key element in the reassignment of the CUG codon in Candida albicans. MA Santos, VM Perreau, MF Tuite The EMBO journal 15 (18), 5060-5068, 1996	99	1996

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