IDH mutation impairs histone demethylation and results in a block to cell differentiation C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ... Nature 483 (7390), 474-478, 2012 | 2216 | 2012 |
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma DM O’Rourke, MLP Nasrallah, A Desai, JJ Melenhorst, K Mansfield, ... Science translational medicine 9 (399), eaaa0984, 2017 | 1666 | 2017 |
Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial M Weller, N Butowski, DD Tran, LD Recht, M Lim, H Hirte, L Ashby, ... The lancet oncology 18 (10), 1373-1385, 2017 | 1038 | 2017 |
A patient-derived glioblastoma organoid model and biobank recapitulates inter-and intra-tumoral heterogeneity F Jacob, RD Salinas, DY Zhang, PTT Nguyen, JG Schnoll, SZH Wong, ... Cell 180 (1), 188-204. e22, 2020 | 802 | 2020 |
Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving … A Maity, N Pore, J Lee, D Solomon, DM O’Rourke Cancer research 60 (20), 5879-5886, 2000 | 353 | 2000 |
Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques L Macyszyn, H Akbari, JM Pisapia, X Da, M Attiah, V Pigrish, Y Bi, S Pal, ... Neuro-oncology 18 (3), 417-425, 2015 | 316 | 2015 |
Induction of ischemic tolerance following brief focal ischemia in rat brain SS Glazier, DM O'Rourke, DI Graham, FA Welsh Journal of Cerebral Blood Flow & Metabolism 14 (4), 545-553, 1994 | 299 | 1994 |
CAR T-cell therapy for glioblastoma: recent clinical advances and future challenges SJ Bagley, AS Desai, GP Linette, CH June, DM O’Rourke Neuro-oncology 20 (11), 1429-1438, 2018 | 295 | 2018 |
Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1–independent mechanism N Pore, S Liu, HK Shu, B Li, D Haas-Kogan, D Stokoe, J Milanini-Mongiat, ... Molecular biology of the cell 15 (11), 4841-4853, 2004 | 295 | 2004 |
Rationally designed anti-HER2/neu peptide mimetic disables P185HER2/neu tyrosine kinases in vitro and in vivo BW Park, HT Zhang, C Wu, A Berezov, X Zhang, R Dua, Q Wang, G Kao, ... Nature biotechnology 18 (2), 194-198, 2000 | 271 | 2000 |
Intraaxial Brain Masses: MR Imaging–based Diagnostic Strategy—Initial Experience1 RN Al-Okaili, J Krejza, JH Woo, RL Wolf, DM O'Rourke, KD Judy, ... Radiology 243 (2), 539-550, 2007 | 261 | 2007 |
A randomized double-blind placebo-controlled phase II trial of dendritic cell vaccine ICT-107 in newly diagnosed patients with glioblastoma PY Wen, DA Reardon, TS Armstrong, S Phuphanich, RD Aiken, ... Clinical Cancer Research 25 (19), 5799-5807, 2019 | 228 | 2019 |
Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α Q Wang, Z He, M Huang, T Liu, Y Wang, H Xu, H Duan, P Ma, L Zhang, ... Nature communications 9 (1), 559, 2018 | 228 | 2018 |
Grading of CNS neoplasms using continuous arterial spin labeled perfusion MR imaging at 3 Tesla RL Wolf, J Wang, S Wang, ER Melhem, DM O'Rourke, KD Judy, JA Detre Journal of Magnetic Resonance Imaging: An Official Journal of the …, 2005 | 220 | 2005 |
Differentiation between glioblastomas, solitary brain metastases, and primary cerebral lymphomas using diffusion tensor and dynamic susceptibility contrast-enhanced MR imaging S Wang, S Kim, S Chawla, RL Wolf, DE Knipp, A Vossough, DM O'Rourke, ... American Journal of Neuroradiology 32 (3), 507-514, 2011 | 216 | 2011 |
PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor (VEGF) mRNA expression in human glioblastoma cells by transactivating … N Pore, S Liu, DA Haas-Kogan, DM O’Rourke, A Maity Cancer research 63 (1), 236-241, 2003 | 213 | 2003 |
Differentiation between glioblastomas and solitary brain metastases using diffusion tensor imaging S Wang, S Kim, S Chawla, RL Wolf, WG Zhang, DM O'Rourke, KD Judy, ... Neuroimage 44 (3), 653-660, 2009 | 198 | 2009 |
The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors CJ Wu, DM O'Rourke, GS Feng, GR Johnson, Q Wang, MI Greene Oncogene 20 (42), 6018-6025, 2001 | 190 | 2001 |
Radiomic MRI signature reveals three distinct subtypes of glioblastoma with different clinical and molecular characteristics, offering prognostic value beyond IDH1 S Rathore, H Akbari, M Rozycki, KG Abdullah, MLP Nasrallah, ZA Binder, ... Scientific reports 8 (1), 5087, 2018 | 174 | 2018 |
Checkpoint blockade reverses anergy in IL-13Rα2 humanized scFv-based CAR T cells to treat murine and canine gliomas Y Yin, AC Boesteanu, ZA Binder, C Xu, RA Reid, JL Rodriguez, DR Cook, ... Molecular Therapy-Oncolytics 11, 20-38, 2018 | 173 | 2018 |