Donald M. O'Rourke
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IDH mutation impairs histone demethylation and results in a block to cell differentiation
C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ...
Nature 483 (7390), 474-478, 2012
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
DM O’Rourke, MLP Nasrallah, A Desai, JJ Melenhorst, K Mansfield, ...
Science translational medicine 9 (399), 2017
Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial
M Weller, N Butowski, DD Tran, LD Recht, M Lim, H Hirte, L Ashby, ...
The Lancet Oncology 18 (10), 1373-1385, 2017
Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving …
A Maity, N Pore, J Lee, D Solomon, DM O’Rourke
Cancer research 60 (20), 5879-5886, 2000
Induction of ischemic tolerance following brief focal ischemia in rat brain
SS Glazier, DM O'Rourke, DI Graham, FA Welsh
Journal of Cerebral Blood Flow & Metabolism 14 (4), 545-553, 1994
Sp1 is involved in Akt-mediated induction of VEGF expression through an HIF-1–independent mechanism
N Pore, S Liu, HK Shu, B Li, D Haas-Kogan, D Stokoe, J Milanini-Mongiat, ...
Molecular biology of the cell 15 (11), 4841-4853, 2004
Rationally designed anti-HER2/neu peptide mimetic disables p185 HER2/neu tyrosine kinases in vitro and in vivo
BW Park, HT Zhang, C Wu, A Berezov, X Zhang, R Dua, Q Wang, G Kao, ...
Nature biotechnology 18 (2), 194-198, 2000
A patient-derived glioblastoma organoid model and biobank recapitulates inter-and intra-tumoral heterogeneity
F Jacob, RD Salinas, DY Zhang, PTT Nguyen, JG Schnoll, SZH Wong, ...
Cell 180 (1), 188-204. e22, 2020
Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques
L Macyszyn, H Akbari, JM Pisapia, X Da, M Attiah, V Pigrish, Y Bi, S Pal, ...
Neuro-oncology 18 (3), 417-425, 2015
Intraaxial Brain Masses: MR Imaging–based Diagnostic Strategy—Initial Experience1
RN Al-Okaili, J Krejza, JH Woo, RL Wolf, DM O'Rourke, KD Judy, ...
Radiology 243 (2), 539-550, 2007
PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor (VEGF) mRNA expression in human glioblastoma cells by transactivating …
N Pore, S Liu, DA Haas-Kogan, DM O’Rourke, A Maity
Cancer research 63 (1), 236-241, 2003
Grading of CNS neoplasms using continuous arterial spin labeled perfusion MR imaging at 3 Tesla
RL Wolf, J Wang, S Wang, ER Melhem, DM O'Rourke, KD Judy, JA Detre
Journal of Magnetic Resonance Imaging: An Official Journal of the …, 2005
Differentiation between glioblastomas, solitary brain metastases, and primary cerebral lymphomas using diffusion tensor and dynamic susceptibility contrast-enhanced MR imaging
S Wang, S Kim, S Chawla, RL Wolf, DE Knipp, A Vossough, DM O'Rourke, ...
American Journal of Neuroradiology 32 (3), 507-514, 2011
The tyrosine phosphatase SHP-2 is required for mediating phosphatidylinositol 3-kinase/Akt activation by growth factors
CJ Wu, DM O'Rourke, GS Feng, GR Johnson, Q Wang, MI Greene
Oncogene 20 (42), 6018-6025, 2001
Differentiation between glioblastomas and solitary brain metastases using diffusion tensor imaging
S Wang, S Kim, S Chawla, RL Wolf, WG Zhang, DM O'Rourke, KD Judy, ...
Neuroimage 44 (3), 653-660, 2009
Constitutive EGFR signaling confers a motile phenotype to neural stem cells
JA Boockvar, D Kapitonov, G Kapoor, J Schouten, GJ Counelis, O Bogler, ...
Molecular and Cellular Neuroscience 24 (4), 1116-1130, 2003
Expression of oncogenic epidermal growth factor receptor family kinases induces paclitaxel resistance and alters β-tubulin isotype expression
RB Montgomery, J Guzman, DM O'Rourke, WL Stahl
Journal of Biological chemistry 275 (23), 17358-17363, 2000
Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells
A Ayuso-Sacido, JA Moliterno, S Kratovac, GS Kapoor, DM O’Rourke, ...
Journal of neuro-oncology 97 (3), 323-337, 2010
Compositions and methods of treating tumors
MI Greene, DM O'rourke, R Murali, BW Park
US Patent 6,417,168, 2002
Murine thioredoxin peroxidase delays neuronal apoptosis and is expressed in areas of the brain most susceptible to hypoxic and ischemic injury
DNA and cell biology 16 (3), 311-321, 1997
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