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| Cation‐selective transporters are critical to the AMPK‐mediated antiproliferative effects of metformin in human breast cancer cells H Cai, Y Zhang, T Han, RS Everett, DR Thakker International journal of cancer 138 (9), 2281-2292, 2016 | 55 | 2016 |
| Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS A Sengupta-Ghosh, SL Dominguez, L Xie, KH Barck, Z Jiang, T Earr, ... Neurobiology of Disease 124, 340-352, 2019 | 32 | 2019 |
| Preclinical and translational pharmacokinetics of a novel THIOMAB™ antibody-antibiotic conjugate against Staphylococcus aureus R Deng, C Zhou, D Li, H Cai, S Sukumaran, M Carrasco-Triguero, O Saad, ... MAbs 11 (6), 1162-1174, 2019 | 29 | 2019 |
| A BCMA/CD16A bispecific innate cell engager for the treatment of multiple myeloma S Kakiuchi-Kiyota, T Ross, HA Wallweber, JR Kiefer, MM Schutten, ... Leukemia 36 (4), 1006-1014, 2022 | 22 | 2022 |
| Efficacious Dose of Metformin for Breast Cancer Therapy is Determined by Cation Transporter Expression in Tumors H Cai, R Everett, DR Thakker British Journal of Pharmacology, 2019 | 22 | 2019 |
| Translational approaches for brain delivery of biologics via cerebrospinal fluid SS Sadekar, M Bowen, H Cai, S Jamalian, H Rafidi, W Shatz‐Binder, ... Clinical Pharmacology & Therapeutics 111 (4), 826-834, 2022 | 19 | 2022 |
| Immune repertoire mining for rapid affinity optimization of mouse monoclonal antibodies YC Hsiao, Y Shang, DM DiCara, A Yee, J Lai, SH Kim, D Ellerman, ... MAbs 11 (4), 735-746, 2019 | 18 | 2019 |
| Sustained activity of novel THIOMAB antibody-antibiotic conjugate against Staphylococcus aureus in a mouse model: Longitudinal pharmacodynamic assessment … C Zhou, H Cai, A Baruch, N Lewin-Koh, M Yang, F Guo, D Xu, R Deng, ... PLoS One 14 (10), e0224096, 2019 | 17 | 2019 |
| Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis J Chavarria-Smith, CPC Chiu, JK Jackman, J Yin, J Zhang, JA Hackney, ... Science Translational Medicine 14 (675), eabp9159, 2022 | 12 | 2022 |
| Anti-LYPD1/CD3 T-cell-dependent bispecific antibody for the treatment of ovarian cancer AA Lo, J Johnston, J Li, D Mandikian, M Hristopoulos, R Clark, D Nickles, ... Molecular Cancer Therapeutics 20 (4), 716-725, 2021 | 10 | 2021 |
| Preclinical pharmacology and safety of RO7297089, a novel anti-BCMA/CD16a bispecific antibody for the treatment of multiple myeloma S Kakiuchi-Kiyota, MM Schutten, AO Adedeji, H Cai, R Hendricks, L Liu, ... Cancer Res 80 (16Supplement), 4556, 2020 | 9 | 2020 |
| Characterization of Tissue Distribution, Catabolism, and Elimination of an Anti–Staphylococcus aureus THIOMAB Antibody-Antibiotic Conjugate in Rats H Cai, V Yip, MV Lee, S Wong, O Saad, S Ma, N Ljumanovic, ... Drug Metabolism and Disposition 48 (11), 1161-1168, 2020 | 8 | 2020 |
| Nonclinical pharmacokinetics, pharmacodynamics, and translational model of RO7297089, a novel anti-BCMA/CD16A bispecific tetravalent antibody for the treatment of multiple myeloma H Cai, S Kakiuchi-Kiyota, R Hendricks, S Zhong, L Liu, AO Adedeji, ... The AAPS Journal 24 (6), 100, 2022 | 7 | 2022 |
| Anti-α-synuclein c-terminal antibodies block PFF uptake and accumulation of phospho-synuclein in preclinical models of Parkinson's disease R Brendza, X Gao, KL Stark, H Lin, SH Lee, C Hu, H Cai, D DiCara, ... Neurobiology of Disease 177, 105969, 2023 | 6 | 2023 |
| Balancing the affinity and pharmacokinetics of antibodies by modulating the size of charge patches on complementarity-determining regions Y Sun, H Cai, Z Hu, CA Boswell, J Diao, C Li, L Zhang, A Shen, CA Teske, ... Journal of Pharmaceutical Sciences 109 (12), 3690-3696, 2020 | 6 | 2020 |
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