| m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways HB Li, J Tong, S Zhu, PJ Batista, EE Duffy, J Zhao, W Bailis, G Cao, ... Nature 548 (7667), 338-342, 2017 | 746 | 2017 |
| The DNA-sensing AIM2 inflammasome controls radiation-induced cell death and tissue injury B Hu, C Jin, HB Li, J Tong, X Ouyang, NM Cetinbas, S Zhu, T Strowig, ... Science 354 (6313), 765-768, 2016 | 321 | 2016 |
| Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells S Zhu, S Ding, P Wang, Z Wei, W Pan, NW Palm, Y Yang, H Yu, HB Li, ... Nature 546 (7660), 667-670, 2017 | 312 | 2017 |
| Recent advances in dynamic m6A RNA modification G Cao, HB Li, Z Yin, RA Flavell Open biology 6 (4), 160003, 2016 | 282 | 2016 |
| m6A mRNA methylation sustains Treg suppressive functions J Tong, G Cao, T Zhang, E Sefik, MC Amezcua Vesely, JP Broughton, ... Cell Research 28 (2), 253-256, 2018 | 274 | 2018 |
| Nature and function of insulator protein binding sites in the Drosophila genome YB Schwartz, D Linder-Basso, PV Kharchenko, MY Tolstorukov, M Kim, ... Genome research 22 (11), 2188-2198, 2012 | 200 | 2012 |
| RNA m6A modification and its function in diseases J Tong, RA Flavell, HB Li Frontiers of medicine 12, 481-489, 2018 | 196 | 2018 |
| A view of nuclear Polycomb bodies V Pirrotta, HB Li Current opinion in genetics & development 22 (2), 101-109, 2012 | 196 | 2012 |
| Cross-talk of four types of RNA modification writers defines tumor microenvironment and pharmacogenomic landscape in colorectal cancer H Chen, J Yao, R Bao, Y Dong, T Zhang, Y Du, G Wang, D Ni, Z Xun, ... Molecular cancer 20, 1-21, 2021 | 145 | 2021 |
| mRNA destabilization by BTG1 and BTG2 maintains T cell quiescence SS Hwang, J Lim, Z Yu, P Kong, E Sefik, H Xu, CCD Harman, LK Kim, ... Science 367 (6483), 1255-1260, 2020 | 143 | 2020 |
| Insulators, Not Polycomb Response Elements, Are Required for Long-Range Interactions between Polycomb Targets in Drosophila melanogaster HB Li, M Müller, IA Bahechar, O Kyrchanova, K Ohno, P Georgiev, ... Molecular and cellular biology 31 (4), 616-625, 2011 | 126 | 2011 |
| m6A modification prevents formation of endogenous double-stranded RNAs and deleterious innate immune responses during hematopoietic development Y Gao, R Vasic, Y Song, R Teng, C Liu, R Gbyli, G Biancon, R Nelakanti, ... Immunity 52 (6), 1007-1021. e8, 2020 | 121 | 2020 |
| Pooled CRISPR screening identifies m6A as a positive regulator of macrophage activation J Tong, X Wang, Y Liu, X Ren, A Wang, Z Chen, J Yao, K Mao, T Liu, ... Science advances 7 (18), eabd4742, 2021 | 115 | 2021 |
| METTL3-mediated m6A RNA methylation promotes the anti-tumour immunity of natural killer cells H Song, J Song, M Cheng, M Zheng, T Wang, S Tian, RA Flavell, S Zhu, ... Nature communications 12 (1), 5522, 2021 | 109 | 2021 |
| m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity J Zhou, X Zhang, J Hu, R Qu, Z Yu, H Xu, H Chen, L Yan, C Ding, Q Zou, ... Science Advances 7 (25), eabg0470, 2021 | 96 | 2021 |
| SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation X Yu, Y Lao, XL Teng, S Li, Y Zhou, F Wang, X Guo, S Deng, Y Chang, ... Nature communications 9 (1), 3157, 2018 | 93 | 2018 |
| Insulators target active genes to transcription factories and polycomb-repressed genes to polycomb bodies HB Li, K Ohno, H Gui, V Pirrotta PLoS genetics 9 (4), e1003436, 2013 | 78 | 2013 |
| m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity Y Qin, B Li, S Arumugam, Q Lu, SM Mankash, J Li, B Sun, J Li, RA Flavell, ... Cell reports 37 (6), 2021 | 67 | 2021 |
| MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche N Wu, H Sun, X Zhao, Y Zhang, J Tan, Y Qi, Q Wang, M Ng, Z Liu, L He, ... Nature 592 (7855), 606-610, 2021 | 66 | 2021 |
| Acylglycerol kinase maintains metabolic state and immune responses of CD8+ T cells Z Hu, G Qu, X Yu, H Jiang, XL Teng, L Ding, Q Hu, X Guo, Y Zhou, ... Cell metabolism 30 (2), 290-302. e5, 2019 | 60 | 2019 |
Richard A. FlavellSterling Professor of Immunobiology, Yale University, HHMI InvestigatorVerified email at yale.edu
