| AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses AS Richard, BS Shim, YC Kwon, R Zhang, Y Otsuka, K Schmitt, F Berri, ... Proceedings of the National Academy of Sciences 114 (8), 2024-2029, 2017 | 229 | 2017 |
| LPCAT3 inhibitors remodel the polyunsaturated phospholipid content of human cells and protect from ferroptosis A Reed, TA Ichu, N Milosevich, B Melillo, MA Schafroth, Y Otsuka, ... ACS chemical biology 17 (6), 1607-1618, 2022 | 63 | 2022 |
| Zika virus-immune plasmas from symptomatic and asymptomatic individuals enhance Zika pathogenesis in adult and pregnant mice BS Shim, YC Kwon, MJ Ricciardi, M Stone, Y Otsuka, F Berri, JM Kwal, ... MBio 10 (4), 10.1128/mbio. 00758-19, 2019 | 30 | 2019 |
| Identification of potent small molecule inhibitors of SARS-CoV-2 entry S Mediouni, H Mou, Y Otsuka, JA Jablonski, RS Adcock, L Batra, ... Slas Discovery 27 (1), 8-19, 2022 | 20 | 2022 |
| Diverse pathways of escape from all well-characterized VRC01-class broadly neutralizing HIV-1 antibodies Y Otsuka, K Schmitt, BD Quinlan, MR Gardner, B Alfant, A Reich, ... PLoS pathogens 14 (8), e1007238, 2018 | 19 | 2018 |
| Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 Mpro/3CLpro in Living Cells SA Moghadasi, MA Esler, Y Otsuka, JT Becker, SN Moraes, CB Anderson, ... MBio 13 (3), e00784-22, 2022 | 16 | 2022 |
| Identification of small-molecule inhibitors of neutral ceramidase (nCDase) via target-based high-throughput screening Y Otsuka, MV Airola, YM Choi, N Coant, J Snider, C Cariello, EM Saied, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 26 (1), 113-121, 2021 | 11 | 2021 |
| An unbiased high‐throughput drug screen reveals a potential therapeutic vulnerability in the most lethal molecular subtype of pancreatic cancer CH Pan, Y Otsuka, BP Sridharan, M Woo, CV Leiton, S Babu, ... Molecular Oncology 14 (8), 1800-1816, 2020 | 11 | 2020 |
| ERAD of proteins containing aberrant transmembrane domains requires ubiquitylation of cytoplasmic lysine residues K Briant, YH Koay, Y Otsuka, E Swanton Journal of cell science 128 (22), 4112-4125, 2015 | 9 | 2015 |
| Neutral ceramidase-active site inhibitor chemotypes and binding modes N Coant, JD Bickel, R Rahaim, Y Otsuka, YM Choi, R Xu, M Simoes, ... Bioorganic chemistry 139, 106747, 2023 | 1 | 2023 |
| Abstract 1217 SARS-CoV-2 Main Protease Inhibitor High-Throughput Screen R Delgado, J Vishwakarma, S Moghadasi, Y Otsuka, L Scampavia, ... Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
| Identification of Potent Small Molecule Inhibitors of SARS-CoV-2 Entry (preprint) S Jablonski, H Mou, Y Otsuka, J Jablonski, RS Adcock, L Batra, D Chung, ... | | 2021 |
| Quality control of transmembrane domains in the secretory pathway Y Otsuka The University of Manchester, Manchester, UK, 2011 | | 2011 |
