| Development of peptide and small‐molecule HIV‐1 fusion inhibitors that target gp41 L Cai, S Jiang ChemMedChem 5 (11), 1813-1824, 2010 | 111 | 2010 |
| Steroidal saponins from Tribulus terrestris L Cai, Y Wu, J Zhang, F Pei, Y Xu, S Xie, D Xu Planta medica 67 (02), 196-198, 2001 | 98 | 2001 |
| Development of small-molecule HIV entry inhibitors specifically targeting gp120 or gp41 L Lu, F Yu, L Cai, A K Debnath, S Jiang Current topics in medicinal chemistry 16 (10), 1074-1090, 2016 | 76 | 2016 |
| Biophysical property and broad anti-HIV activity of albuvirtide, a 3-maleimimidopropionic acid-modified peptide fusion inhibitor H Chong, X Yao, C Zhang, L Cai, S Cui, Y Wang, Y He PLoS One 7 (3), e32599, 2012 | 76 | 2012 |
| A facile surfactant critical micelle concentration determination L Cai, M Gochin, K Liu Chemical communications 47 (19), 5527-5529, 2011 | 67 | 2011 |
| Combinations of the first and next generations of human immunodeficiency virus (HIV) fusion inhibitors exhibit a highly potent synergistic effect against enfuvirtide-sensitive … C Pan, L Cai, H Lu, Z Qi, S Jiang Journal of virology 83 (16), 7862-7872, 2009 | 64 | 2009 |
| A novel fluorescence intensity screening assay identifies new low-molecular-weight inhibitors of the gp41 coiled-coil domain of human immunodeficiency virus type 1 L Cai, M Gochin Antimicrobial agents and chemotherapy 51 (7), 2388-2395, 2007 | 60 | 2007 |
| Biochemistry and biophysics of HIV-1 gp41-membrane interactions and implications for HIV-1 envelope protein mediated viral-cell fusion and fusion inhibitor design L Cai, M Gochin, K Liu Current topics in medicinal chemistry 11 (24), 2959-2984, 2011 | 58 | 2011 |
| A recombinant vaccine of H5N1 HA1 fused with foldon and human IgG Fc induced complete cross-clade protection against divergent H5N1 viruses L Du, VHC Leung, X Zhang, J Zhou, M Chen, W He, HY Zhang, ... PloS one 6 (1), e16555, 2011 | 57 | 2011 |
| Structural characterization of human RPA sequential binding to single-stranded DNA using ssDNA as a molecular ruler L Cai, M Roginskaya, Y Qu, Z Yang, Y Xu, Y Zou Biochemistry 46 (28), 8226-8233, 2007 | 53 | 2007 |
| Discovery of HIV fusion inhibitors targeting gp41 using a comprehensive α-helix mimetic library LR Whitby, KE Boyle, L Cai, X Yu, M Gochin, DL Boger Bioorganic & medicinal chemistry letters 22 (8), 2861-2865, 2012 | 42 | 2012 |
| Design, synthesis, and biological evaluation of highly potent small molecule–peptide conjugates as new HIV-1 fusion inhibitors C Wang, W Shi, L Cai, L Lu, Q Wang, T Zhang, J Li, Z Zhang, K Wang, ... Journal of medicinal chemistry 56 (6), 2527-2539, 2013 | 40 | 2013 |
| Conjugation of a nonspecific antiviral sapogenin with a specific HIV fusion inhibitor: a promising strategy for discovering new antiviral therapeutics C Wang, L Lu, H Na, X Li, Q Wang, X Jiang, X Xu, F Yu, T Zhang, J Li, ... Journal of Medicinal Chemistry 57 (17), 7342-7354, 2014 | 39 | 2014 |
| Covalent fusion inhibitors targeting HIV-1 gp41 deep pocket Y Bai, H Xue, K Wang, L Cai, J Qiu, S Bi, L Lai, M Cheng, S Liu, K Liu Amino acids 44, 701-713, 2013 | 39 | 2013 |
| An isothermal titration calorimetric method to determine the kinetic parameters of enzyme catalytic reaction by employing the product inhibition as probe L Cai, A Cao, L Lai Analytical biochemistry 299 (1), 19-23, 2001 | 35 | 2001 |
| The role of amphiphilicity and negative charge in glycoprotein 41 interactions in the hydrophobic pocket M Gochin, L Cai Journal of medicinal chemistry 52 (14), 4338-4344, 2009 | 29 | 2009 |
| A fluorescence assay for rapid detection of ligand binding affinity to HIV-1 gp41 M Gochin, R Savage, S Hinckley, L Cai Walter de Gruyter 387 (4), 477-483, 2006 | 29 | 2006 |
| Mutations of Gln64 in the HIV-1 gp41 N-terminal heptad repeat render viruses resistant to peptide HIV fusion inhibitors targeting the gp41 pocket X Yu, L Lu, L Cai, P Tong, S Tan, P Zou, F Meng, Y Chen, S Jiang Journal of virology 86 (1), 589-593, 2012 | 26 | 2012 |
| Stable extended human immunodeficiency virus type 1 gp41 coiled coil as an effective target in an assay for high-affinity fusion inhibitors L Cai, E Balogh, M Gochin Antimicrobial agents and chemotherapy 53 (6), 2444-2449, 2009 | 24 | 2009 |
| A novel chimeric protein-based HIV-1 fusion inhibitor targeting gp41 glycoprotein with high potency and stability C Pan, L Cai, H Lu, L Lu, S Jiang Journal of Biological Chemistry 286 (32), 28425-28434, 2011 | 23 | 2011 |
