| Exome-wide association study of plasma lipids in> 300,000 individuals DJ Liu, GM Peloso, H Yu, AS Butterworth, X Wang, A Mahajan, ... Nature genetics 49 (12), 1758-1766, 2017 | 532 | 2017 |
| ANGPTL3 deficiency and protection against coronary artery disease NO Stitziel, AV Khera, X Wang, AJ Bierhals, AC Vourakis, AE Sperry, ... Journal of the American College of Cardiology 69 (16), 2054-2063, 2017 | 431 | 2017 |
| Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins S Banskota, A Raguram, S Suh, SW Du, JR Davis, EH Choi, X Wang, ... Cell 185 (2), 250-265. e16, 2022 | 282 | 2022 |
| In vivo base editing of PCSK9 (proprotein convertase subtilisin/kexin type 9) as a therapeutic alternative to genome editing AC Chadwick, X Wang, K Musunuru Arteriosclerosis, thrombosis, and vascular biology 37 (9), 1741-1747, 2017 | 223 | 2017 |
| Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition KS Small, M Todorčević, M Civelek, JS El-Sayed Moustafa, X Wang, ... Nature genetics 50 (4), 572-580, 2018 | 164 | 2018 |
| CRISPR-Cas9 Targeting of PCSK9 in Human Hepatocytes In Vivo—Brief Report X Wang, A Raghavan, T Chen, L Qiao, Y Zhang, Q Ding, K Musunuru Arteriosclerosis, thrombosis, and vascular biology 36 (5), 783-786, 2016 | 161 | 2016 |
| Large, diverse population cohorts of hiPSCs and derived hepatocyte-like cells reveal functional genetic variation at blood lipid-associated loci EE Pashos, Y Park, X Wang, A Raghavan, W Yang, D Abbey, DT Peters, ... Cell stem cell 20 (4), 558-570. e10, 2017 | 143 | 2017 |
| Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol YX Xu, V Redon, H Yu, W Querbes, J Pirruccello, A Liebow, A Deik, ... Atherosclerosis 268, 196-206, 2018 | 103 | 2018 |
| Tollip, an intracellular trafficking protein, is a novel modulator of the transforming growth factor-β signaling pathway L Zhu, L Wang, X Luo, Y Zhang, Q Ding, X Jiang, X Wang, Y Pan, Y Chen Journal of Biological Chemistry 287 (47), 39653-39663, 2012 | 91 | 2012 |
| Efficient in vivo base editing via single adeno-associated viruses with size-optimized genomes encoding compact adenine base editors JR Davis, X Wang, IP Witte, TP Huang, JM Levy, A Raguram, S Banskota, ... Nature Biomedical Engineering 6 (11), 1272-1283, 2022 | 82 | 2022 |
| RKTG sequesters B-Raf to the Golgi apparatus and inhibits the proliferation and tumorigenicity of human malignant melanoma cells F Fan, L Feng, J He, X Wang, X Jiang, Y Zhang, Z Wang, Y Chen Carcinogenesis 29 (6), 1157-1163, 2008 | 73 | 2008 |
| Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis X Luo, Y Zhang, X Ruan, X Jiang, L Zhu, X Wang, Q Ding, W Liu, Y Pan, ... Diabetes 60 (5), 1435-1445, 2011 | 70 | 2011 |
| PAQR3 plays a suppressive role in the tumorigenesis of colorectal cancers X Wang, X Li, F Fan, S Jiao, L Wang, L Zhu, Y Pan, G Wu, ZQ Ling, J Fang, ... Carcinogenesis 33 (11), 2228-2235, 2012 | 66 | 2012 |
| PAQR3 modulates insulin signaling by shunting phosphoinositide 3-kinase p110α to the Golgi apparatus X Wang, L Wang, L Zhu, Y Pan, F Xiao, W Liu, Z Wang, F Guo, Y Liu, ... Diabetes 62 (2), 444-456, 2013 | 64 | 2013 |
| Regulation of G-protein signaling by RKTG via Sequestration of the Gβγ subunit to the golgi apparatus Y Jiang, X Xie, Y Zhang, X Luo, X Wang, F Fan, D Zheng, Z Wang, Y Chen Molecular and cellular biology 30 (1), 78-90, 2010 | 54 | 2010 |
| FOXA1 defines cancer cell specificity G Zhang, Y Zhao, Y Liu, LP Kao, X Wang, B Skerry, Z Li Science advances 2 (3), e1501473, 2016 | 49 | 2016 |
| PAQR3 has modulatory roles in obesity, energy metabolism, and leptin signaling L Wang, X Wang, Z Li, T Xia, L Zhu, B Liu, Y Zhang, F Xiao, Y Pan, Y Liu, ... Endocrinology 154 (12), 4525-4535, 2013 | 49 | 2013 |
| Hepatic deletion of Smad7 in mouse leads to spontaneous liver dysfunction and aggravates alcoholic liver injury L Zhu, L Wang, X Wang, X Luo, L Yang, R Zhang, H Yin, D Xie, Y Pan, ... PLoS One 6 (2), e17415, 2011 | 47 | 2011 |
| Angiopoietin-like 3: from discovery to therapeutic gene editing X Wang, K Musunuru Basic to Translational Science 4 (6), 755-762, 2019 | 42 | 2019 |
| Confirmation of Causal rs9349379-PHACTR1 Expression Quantitative Trait Locus in Human-Induced Pluripotent Stem Cell Endothelial Cells X Wang, K Musunuru Circulation: Genomic and Precision Medicine 11 (10), e002327, 2018 | 32 | 2018 |
Lu ZhuProfessor, Tianjin Medical University, Tianjin, ChinaVerified email at tmu.edu.cn
